scholarly journals A Prospective Study and Clinical Trial Comparing Modified Limberg Transposition Flap Reconstruction with Excision and Primary Closure in the Treatment of Uncomplicated Sacrococcygeal Pilonidal Sinus

2017 ◽  
Vol 05 (03) ◽  
pp. 19235-19241
Author(s):  
Atul Kumar Vyas ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 241-244
Author(s):  
Samarendra Satpathy ◽  
Ashok Kumar Nayak ◽  
Sanjay Kumar Mahapatra ◽  
Akhil Unnikrishnan

Pilonidal sinus is a blind ending track containing hair follicles within it and is primarily a disease involving sacrococcygeal region. The exact etiology of this disease process is unknown and is still controversial. There are various treatment methods for pilonidal sinus and the preferred method is Limberg flap reconstruction surgery due to its less complications and less recurrence. Our study was a prospective study including 28 patients who were admitted for pilonidal sinus and operated by Limberg flap reconstruction surgery at Veer Surendra Sai Institute of Medical Sciences And Research from January 2018 to June 2020. Our study included 28 patients, and the female to male ratio is 1:13. Duration of symptoms had a range from 1-4 months and the mean age of the study population was 28.5 year. Patients underwent Limberg flap reconstruction surgery and 89.28% followed a normal course after surgery , 7.14% developed seroma and 3.57% developed surgical site infection in their post-operative period. Limberg flap reconstruction surgery is the most preferred method of treatment for pilonidal sinus because of its low infection and recurrence rates, better aesthetic results after surgery and short duration of hospital stay.


2007 ◽  
Vol 45 (2) ◽  
pp. 132-135 ◽  
Author(s):  
Fahim Mohamed ◽  
M. Roshini Sooriyarachchi ◽  
Lalith Senarathna ◽  
Shifa Azhar ◽  
M.H. Rezvi Sheriff ◽  
...  

PEDIATRICS ◽  
1972 ◽  
Vol 49 (4) ◽  
pp. 638-639
Author(s):  
P. A. Voûte ◽  
J. Lemerle

The International Society of Pediatric Oncology (ISPO) is planning a clinical therapeutic trial on nephroblastoma in Europe. Large agreement exists on the treatment of these tumors; the principal modalities are surgery, radiation therapy, and chemotherapy. However, there are some unanswered questions as to the value of different forms of administration of radiation and chemotherapy, which we feel could best be elucidated by a prospective study in the form of a clinical trial. A trial has been going on in the United States for 2 years.


1990 ◽  
Vol 4 (2) ◽  
pp. 143-146 ◽  
Author(s):  
Christian Aligne ◽  
Michel Farcot ◽  
Jean-Pierre Favre ◽  
Ghassan Alnashawati ◽  
Francesco De Simone ◽  
...  

2006 ◽  
Vol 42 (5) ◽  
pp. 336-343 ◽  
Author(s):  
Petra A. Mertens ◽  
Sheila Torres ◽  
Carl Jessen

A double-blind, placebo-controlled clinical trial was conducted to determine the efficacy of clomipramine hydrochloride in cats with psychogenic alopecia. Twenty-five cats were randomly assigned to receive clomipramine hydrochloride (0.5 mg/kg orally q 24 hours) or placebo for 56 days. Eleven cats in each group completed the trial. The results of this study showed that clomipramine hydrochloride failed to demonstrate significant changes in the number of grooming bouts, hair regrowth, and the area of alopecia in cats with psychogenic alopecia when compared to a placebo. It was uncertain whether these results reflected a lack of drug efficacy, insufficient treatment duration, or an insufficient number of cases enrolled.


2018 ◽  
Vol 119 (4) ◽  
pp. 148-155 ◽  
Author(s):  
Abdulcabbar Kartal ◽  
Hüseyin Onur Aydın ◽  
Mehmet Oduncu ◽  
Murat Ferhat Ferhatoğlu ◽  
Taner Kıvılcım ◽  
...  

Our study aims to compare the surgical outcome of Limberg transposition flap, Karydakis flap, and primary closure after excision to treat sacrococcygeal pilonidal sinus disease. A total of 634 patients with pilonidal sinus who underwent surgery were evaluated retrospectively from January 2014 to January 2016. The patients were divided into three groups. Limberg transposition flap (LTF) was performed in 131 patients (group 1), Karydakis flap (KF) was performed in 232 patients (group 2) and primary closure (PC) after excision was performed in 271 patients (group 3). Patient demographics, operative and postoperative outcomes were recorded and analyzed retrospectively. The mean age (p=0.98), sex ratio (p=0.74) and removed sinus volume (p=0.67) were not statistically different between groups. Mean operative time was 54.3 ± 6.4 min for group 1, 46.8 ± 10.5 min for group 2, and 26.9 ± 5.8 min for group 3 respectively (p=0.01). When the length of hospital stay was compared, there was a significant difference in favor of primary closure (p=0.01). Regarding early surgical complication, Karydakis flap technique was superior to other groups (p<0.001). The recurrent rate was higher in the primary closure group (p<0.001). In our study, the primary closure method regarding the duration of surgery and hospitalization; Karydakis method regarding postoperative complications (seroma, hematoma, wound dissociation, infection, recurrence) were superior to the other two methods.


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