scholarly journals Fine Needle Aspiration Cytology in Salivary Gland Swellings- A Cross Sectional Study in a Tertiary Care Centre

2017 ◽  
Vol 05 (05) ◽  
pp. 22271-22276
Author(s):  
Dr Nowshad .M ◽  
Keyword(s):  
Tertiary Care ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Care Centre ◽  
Sectional Study ◽  
Tertiary Care Centre ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Solitary Thyroid Nodules - Validity of Ultrasonography, Fine Needle Aspiration Cytology and Sestamibi in Detecting Thyroid Malignancies - A Cross-Sectional Study in Kerala

2021 ◽  
Vol 8 (31) ◽  
pp. 2885-2889
Author(s):  
Shilpa Suresh ◽  
Riju R. Menon ◽  
Pradeep Jacob ◽  
Gopalakrishnan Nair C
Keyword(s):  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Sestamibi Scintigraphy ◽  
Needle Aspiration Cytology ◽  
Thyroid Malignancies

BACKGROUND The diagnosis of thyroid malignancies continues to remain a challenge, due to lack of specificity with various modalities, and intrinsic variability with clinical examination. Although histopathological diagnosis is confirmatory, there is a need for pre-surgical assessment and confirmation, which will prove to be useful in decision making regarding the course of management. The present study was carried out to evaluate the validity of various modalities for detection of thyroid malignancies. METHODS This cross-sectional study was carried out among 40 patients who presented to the outpatient clinic with thyroid nodules. All the participants were evaluated by ultrasound, fine needle aspiration cytology (FNAC) and sestamibi scintigraphy. All the participants were taken up for surgery and the resected specimen was sent for histopathology for confirmatory diagnosis. RESULTS Ultrasound and FNAC detected malignancy in 25 % of the participants, while sestamibi scintigraphy detected malignancy in 30 % of the participants. Based on histopathology, the gold standard confirmatory test, malignancy was detected in 35 % of the participants. It was observed that the sensitivity was highest for FNAC (75 %) followed by TC methoxyisobutylisonitrile (TC MIBI) (50 %). Specificity was highest for FNAC (95 %) followed by ultrasound (88 %) (P < 0.0001). CONCLUSIONS FNAC has the highest sensitivity and specificity while ultrasound and sestamibi have comparable specificity. There is a high probability of malignancy when the delayed image in sestamibi scintigraphy shows retention. MIBI may prove to be useful in differentiating benign and malignant follicular lesions. KEYWORDS Papillary Carcinoma, Histopathology, Thyroid Nodule, Sestamibi, FNAC

scholarly journals Comparison between fine-needle aspiration cytology and histopathology in leprosy: A cross-sectional study

2021 ◽  
Vol 0 ◽  
pp. 1-6
Author(s):  
Swapna Dominic ◽  
N. Asokan ◽  
G. Nandakumar ◽  
Biju George
Keyword(s):  
Gold Standard ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Kappa Statistics ◽  
Sectional Study ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Objectives: The objectives of the study were (1) to study the fine-needle aspiration cytology (FNAC) features of skin lesions of leprosy, (2) to determine the agreement between FNAC and histopathology to classify leprosy into different groups of the spectrum, and (3) to determine the sensitivity and specificity of FNAC to classify leprosy into different groups of the spectrum against the gold standard of histopathology. Materials and Methods: All newly diagnosed cases of leprosy who attended the outpatient department of dermatology and venereology of a tertiary referral center during the 16 months study period were included in this cross-sectional study. Based on FNAC and histopathology, patients were classified into different groups of the spectrum. Agreement between FNAC and histopathology to classify leprosy was determined by Kappa statistics. Sensitivity and specificity of FNAC to classify leprosy were determined against the gold standard of histopathology. Results: All the 47 study participants had histopathology features of leprosy. FNAC could obtain adequate aspirate in 30 patients (63.8%), who were considered for further analysis. There was moderate agreement (76.6%) between classification of leprosy by FNAC and histopathology on Kappa statistics (Kappa value 0.766). FNAC showed 80–100% sensitivity and 84–100% specificity to classify leprosy against the gold standard of histopathology. Limitations: Small sample size. Conclusion: When adequate aspirate is obtained, FNAC could serve as a useful tool in classification of leprosy.

scholarly journals Age distribution and types of breast lesions among Afghan women diagnosed by fine needle aspiration cytology (FNAC) at a tertiary care centre in Afghanistan: a descriptive cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e037513
Author(s):  
Ramin Saadaat ◽  
Jamshid Abdul-Ghafar ◽  
Ahmed Maseh Haidary ◽  
Soma Rahmani ◽  
Nooria Atta
Keyword(s):  
Age Distribution ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Breast Diseases ◽  
Breast Lesions ◽  
Sectional Study ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Needle Aspiration Cytology

ObjectivesIn Afghanistan, breast diseases are a common reason for women to visit hospitals. This is the first study in Afghanistan aimed to describe the age distribution and types of breast diseases among patients diagnosed by fine needle aspiration cytology.DesignDescriptive cross-sectional study.SettingFrench Medical Institute for Mothers and Children, Kabul, Afghanistan.ParticipantsThe study included 650 patients with breast lesions between 1 April 2015 and 1 April 2019.ResultsThe mean age of diagnosis was 35.38 (SD ±13.11) years, ranging from 15 to 75 years. The most common diagnosis was cancer (24% of all cases). The second most common diagnosed lesion was fibroadenoma, constituting 22.4%, and the third most common lesion was fibrocystic changes, with 15.4% of cases. Inflammatory conditions were diagnosed in 9.7% of cases, granulomatous inflammation in 9.1%, lesions only suspicious for malignancy in 5.5%, lipoma in 2.8% and miscellaneous benign lesions in 11.1%. Cancer was diagnosed at the youngest age of 20 years. Cancer was more common on the left side (62%), and only one case (0.9%) was bilateral.ConclusionOur study showed that cancer was the most commonly diagnosed lesion and was reported at younger ages too. This suggests that physicians should not ignore any breast lump in younger patients and that the possibility of cancer must be considered. Further country-wide studies are suggested to assess breast cancer and associated risk factors.

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