scholarly journals Age distribution and types of breast lesions among Afghan women diagnosed by fine needle aspiration cytology (FNAC) at a tertiary care centre in Afghanistan: a descriptive cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e037513
Author(s):  
Ramin Saadaat ◽  
Jamshid Abdul-Ghafar ◽  
Ahmed Maseh Haidary ◽  
Soma Rahmani ◽  
Nooria Atta
Keyword(s):  
Age Distribution ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Breast Diseases ◽  
Breast Lesions ◽  
Sectional Study ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Needle Aspiration Cytology

ObjectivesIn Afghanistan, breast diseases are a common reason for women to visit hospitals. This is the first study in Afghanistan aimed to describe the age distribution and types of breast diseases among patients diagnosed by fine needle aspiration cytology.DesignDescriptive cross-sectional study.SettingFrench Medical Institute for Mothers and Children, Kabul, Afghanistan.ParticipantsThe study included 650 patients with breast lesions between 1 April 2015 and 1 April 2019.ResultsThe mean age of diagnosis was 35.38 (SD ±13.11) years, ranging from 15 to 75 years. The most common diagnosis was cancer (24% of all cases). The second most common diagnosed lesion was fibroadenoma, constituting 22.4%, and the third most common lesion was fibrocystic changes, with 15.4% of cases. Inflammatory conditions were diagnosed in 9.7% of cases, granulomatous inflammation in 9.1%, lesions only suspicious for malignancy in 5.5%, lipoma in 2.8% and miscellaneous benign lesions in 11.1%. Cancer was diagnosed at the youngest age of 20 years. Cancer was more common on the left side (62%), and only one case (0.9%) was bilateral.ConclusionOur study showed that cancer was the most commonly diagnosed lesion and was reported at younger ages too. This suggests that physicians should not ignore any breast lump in younger patients and that the possibility of cancer must be considered. Further country-wide studies are suggested to assess breast cancer and associated risk factors.

Comparison of Mammography and Ultrasonography in the Diagnosis of Breast Lesions with Fine Needle Aspiration Cytology – A Cross Sectional Study in East Godavari District, Andhra Pradesh

2021 ◽  
Vol 8 (39) ◽  
pp. 3429-3434
Author(s):  
Sowmya D. ◽  
Anusha S ◽  
Prasanna Pidaparti L.V.S.S.N. ◽  
Jaya Chandra T. ◽  
Mythri Priyadarshini V.
Keyword(s):  
Diagnostic Accuracy ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Breast Lesions ◽  
Sectional Study ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

BACKGROUND Breast cancer is the second most common malignancy and most common among women next to lung cancer. A small lump in the breast leads to great physical, emotional, and psychological trauma to the victim and as well as family. In addition to clinical examination, imaging modalities like mammography (MG), ultrasonography (USG), cytological diagnosis by fine needle aspiration cytology (FNAC) and tissue diagnosis were used for the diagnosis. These diagnostic techniques have certain pitfalls in addition to their advantages. A study was conducted to evaluate the breast lesions according to breast imaging reporting and data system using MG and USG, correlation with FNAC. METHODS It was a cross-sectional study, conducted in the Department of Radio-diagnosis, GSL Medical College, Rajahmundry from January 2018 to June 2019, over a period of 18 months. An informed consent was taken from all the participants. The individual with palpable breast lesions detected in clinical examination were included. Physiological swelling, ulcerated and fungal breast growths were not considered. After the detailed clinical history, physical examination, MG and USG were performed, proceeded for FNAC, smears were stained with Leishman and Papanicolaou stain. Statistical analysis was performed by Statistical Package for Social Sciences (SPSS version 20.0). Descriptive data was presented in the form of mean, standard deviation and percentages. Chi-square test was done to assess the association among various categorical data, P < 0.05 was considered statistically significant. RESULTS Total 142 participants were included, maximum number belong to 41 to 50 years, 0.7 % were male. Right side lesion was the predominant. With FNAC, the sensitivity, specificity and the diagnostic accuracy were 86.5 %, 97.8 % and 93.7 %, respectively for benign breast lesions (BBL) diagnosis and 96.7 %, 84.6 %, 92.25 % respectively for malignant breast lesions (MBL) diagnosis. CONCLUSIONS The sensitivity, specificity and diagnostic accuracy was observed to be higher in diagnosis of both BBL and MBL with the combined modalities. KEYWORDS Breast Lesions, Benign, Malignant

Adequacy of Fine-Needle Aspiration Cytology for Breast Lesions: The SurePath® Liquid-Based Technique versus Conventional Smears

2015 ◽  
Vol 59 (3) ◽  
pp. 253-257 ◽  
Author(s):  
José Eleutério Jr. ◽  
Alessa Aragão ◽  
Diane Isabelle Magno Cavalcante
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Breast Lesions ◽  
Cystic Lesions ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Cytology Study

Objective: We aimed to assess the cytological findings from fine-needle aspiration (FNA) of breast lesions with conventional smear (CS) and SurePath® (SP) cytology. Study Design: This was a cross-sectional study of women who underwent FNA from January 2012 to June 2013 for breast lesions with benign ultrasonography impressions in Fortaleza, Brazil. Two groups were formed. The first was composed of 102 samples subjected to CS and the second of 65 samples subjected to SP. The number of smears, the cellularity and the diagnostic hypotheses were compared. Fisher's exact tests with 95% confidence intervals were applied. Results: The women ranged in age from 22 to 75 years. SP cytology indicated greater cellularity than CS for the cystic lesions (p < 0.05). In the CS group, 72.5% of the samples required 3-4 slides, but in the SP group, only 9.2% required a second slide. The cellularity of the cystic samples was significantly greater with the SP method (p < 0.01). Conclusion: In FNA cytology of the breast, SP is a tool that is comparable to CS, but with the added benefits of better cellularity results for cystic lesions and requiring fewer slides for analysis.

Solitary Thyroid Nodules - Validity of Ultrasonography, Fine Needle Aspiration Cytology and Sestamibi in Detecting Thyroid Malignancies - A Cross-Sectional Study in Kerala

2021 ◽  
Vol 8 (31) ◽  
pp. 2885-2889
Author(s):  
Shilpa Suresh ◽  
Riju R. Menon ◽  
Pradeep Jacob ◽  
Gopalakrishnan Nair C
Keyword(s):  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Sestamibi Scintigraphy ◽  
Needle Aspiration Cytology ◽  
Thyroid Malignancies

BACKGROUND The diagnosis of thyroid malignancies continues to remain a challenge, due to lack of specificity with various modalities, and intrinsic variability with clinical examination. Although histopathological diagnosis is confirmatory, there is a need for pre-surgical assessment and confirmation, which will prove to be useful in decision making regarding the course of management. The present study was carried out to evaluate the validity of various modalities for detection of thyroid malignancies. METHODS This cross-sectional study was carried out among 40 patients who presented to the outpatient clinic with thyroid nodules. All the participants were evaluated by ultrasound, fine needle aspiration cytology (FNAC) and sestamibi scintigraphy. All the participants were taken up for surgery and the resected specimen was sent for histopathology for confirmatory diagnosis. RESULTS Ultrasound and FNAC detected malignancy in 25 % of the participants, while sestamibi scintigraphy detected malignancy in 30 % of the participants. Based on histopathology, the gold standard confirmatory test, malignancy was detected in 35 % of the participants. It was observed that the sensitivity was highest for FNAC (75 %) followed by TC methoxyisobutylisonitrile (TC MIBI) (50 %). Specificity was highest for FNAC (95 %) followed by ultrasound (88 %) (P < 0.0001). CONCLUSIONS FNAC has the highest sensitivity and specificity while ultrasound and sestamibi have comparable specificity. There is a high probability of malignancy when the delayed image in sestamibi scintigraphy shows retention. MIBI may prove to be useful in differentiating benign and malignant follicular lesions. KEYWORDS Papillary Carcinoma, Histopathology, Thyroid Nodule, Sestamibi, FNAC

scholarly journals Comparison between fine-needle aspiration cytology and histopathology in leprosy: A cross-sectional study

2021 ◽  
Vol 0 ◽  
pp. 1-6
Author(s):  
Swapna Dominic ◽  
N. Asokan ◽  
G. Nandakumar ◽  
Biju George
Keyword(s):  
Gold Standard ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Kappa Statistics ◽  
Sectional Study ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Objectives: The objectives of the study were (1) to study the fine-needle aspiration cytology (FNAC) features of skin lesions of leprosy, (2) to determine the agreement between FNAC and histopathology to classify leprosy into different groups of the spectrum, and (3) to determine the sensitivity and specificity of FNAC to classify leprosy into different groups of the spectrum against the gold standard of histopathology. Materials and Methods: All newly diagnosed cases of leprosy who attended the outpatient department of dermatology and venereology of a tertiary referral center during the 16 months study period were included in this cross-sectional study. Based on FNAC and histopathology, patients were classified into different groups of the spectrum. Agreement between FNAC and histopathology to classify leprosy was determined by Kappa statistics. Sensitivity and specificity of FNAC to classify leprosy were determined against the gold standard of histopathology. Results: All the 47 study participants had histopathology features of leprosy. FNAC could obtain adequate aspirate in 30 patients (63.8%), who were considered for further analysis. There was moderate agreement (76.6%) between classification of leprosy by FNAC and histopathology on Kappa statistics (Kappa value 0.766). FNAC showed 80–100% sensitivity and 84–100% specificity to classify leprosy against the gold standard of histopathology. Limitations: Small sample size. Conclusion: When adequate aspirate is obtained, FNAC could serve as a useful tool in classification of leprosy.

scholarly journals Trends in symptomatology of thyroid malignancy in southern India and the efficacy of targeted fine needle aspiration cytology with ultrasonography guidance in diagnosis

2019 ◽  
Vol 6 (10) ◽  
pp. 3744
Author(s):  
C. Kiran Kailas ◽  
T. Nazareth Solomon ◽  
Punitha Thetraravu Oli ◽  
Sandeep Jose
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
The United States ◽  
Needle Aspiration ◽  
Cross Sectional Study ◽  
Thyroid Malignancy ◽  
Aspiration Cytology ◽  
Cross Sectional ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Thyroid cancers are on the rise all over the world. Studies have shown a tripling incidence of thyroid cancer in the United States in the past 35 years. Similar studies from Korea have also shown similar trends of 15 times increase in incidence. This study aims at assessing the recent trends in clinical presentation of thyroid malignancy and the efficacy of ultrasound targeted fine needle aspiration cytology (FNAC) in the diagnosis of thyroid malignancy.Methods: A cross sectional study was conducted involving 275 patients with thyroid disorders treated in the department of General Surgery at Dr. Somervell Memorial CSI Medical College, Trivandrum, India. Chi-square test was done for statistical test of significance and odds ratio for strength of association.Results: In this study group, 89% of the patients presented with swelling in front of the neck as chief complaint both in benign and malignancy. Swelling in front of the neck is the predominant symptom in thyroid malignancy. 52% of patients presented with the described symptoms of more than 6 months duration. The specificity of USG guided FNAC is 90% in diagnosing malignancy in goitre in this study group.Conclusions: The commonest symptom of thyroid malignancy was a painless swelling in the front of the neck. Most common thyroid pathology presenting as thyroid swelling was multinodular goitre. Nearly half of the patients presenting with symptoms more than 6 months had thyroid malignancy. FNAC under ultrasound guidance is an inexpensive accurate and practical investigation for evaluation of thyroid carcinomas.

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