Association of blood vitamin D levels with the outcomes of assisted reproductive technology programs

2016 ◽  
Vol 8_2016 ◽  
pp. 93-98 ◽  
Author(s):  
Naimi Z.M.S. Naimi ◽  
Kalinina E.A. Kalinina ◽  
Donnikov A.E. Donnikov ◽  
Alieva K.U. Alieva ◽  
Keyword(s):  
Vitamin D ◽  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Vitamin D Levels ◽  
Technology Programs

Roles of Vitamin D in Reproductive Systems and Assisted Reproductive Technology

Endocrinology ◽  
2020 ◽  
Vol 161 (4) ◽  
Author(s):  
Yilu Chen ◽  
Xu Zhi
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trials ◽  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Controlled Trials ◽  
Reproductive Systems ◽  
Male And Female ◽  
Vitamin D Receptors ◽  
Randomized Controlled ◽  
Vitamin D Levels

Abstract Vitamin D, an essential steroid hormone in the human body, plays an important role in not only the regulation of calcium and phosphorus metabolism, but also in various physiological processes, such as cell differentiation and apoptosis, inflammation, and insulin resistance. Vitamin D receptors are widely distributed in male and female reproductive systems, suggesting that vitamin D is essential for fertility. Because vitamin D deficiency is highly prevalent around the world, this review aims to discuss the potential functions of vitamin D in male and female reproductive systems and the associations between vitamin D and assisted reproductive technology (ART) outcomes. Vitamin D is involved in many physiological reproductive processes, including steroidogenesis, spermatogenesis, and acrosome reaction. It is correlated with sperm quality, ovarian reserve, polycystic ovarian syndrome, and endometriosis, among others. Controversial clinical findings on vitamin D levels and ART outcomes were revealed in this review, and demonstrations of efficacy for human fertility in randomized controlled trials of vitamin D supplementation are notably lacking. Thus, further studies are highly required involving molecular mechanisms among different species and human populations, as well as randomized controlled trials.

scholarly journals Significance of disorders of proteomic profile of follicular fluid for predicting the effectiveness of in vitro fertilisation in women with infertility

2018 ◽  
Vol 99 (3) ◽  
pp. 496-503
Author(s):  
O S Zolotykh ◽  
S V Lomteva ◽  
K Yu Sagamonova
Keyword(s):  
Assisted Reproductive Technology ◽  
Follicular Fluid ◽  
Molecular Mechanisms ◽  
Reproductive Technologies ◽  
Reproductive Technology ◽  
In Vitro Fertilisation ◽  
Proteomic Profile ◽  
Technology Programs ◽  
Group 2

Aim. To study the proteomic profile of follicular fluid in patients with infertility in assisted reproductive technology programs. Methods. The study included women with infertility included in assisted reproductive technology programs: 15 women who had in vitro fertilisation which resulted in pregnancy (group 1) and 16 women with a negative result of this program (group 2). Fractionation of the follicular fluid samples was performed using the sets of special magnetic beads. Proteomic profiling was performed by tandem MALDI-mass-spectrometry. The anti-Müllerian hormone level was measured by ELISA. Results. The study revealed differences in the detectability of follicular fluid proteins with different regulatory properties in patients of groups 1 and 2. With the negative outcome of in vitro fertilisation, expression of a number of proteins involved in the processes of folliculogenesis, ovulation, selection of the dominant follicle, as well as proteins necessary for the development of the zygote and blastula was reduced in females' follicular fluid. Increased expression in women from group 2 was registered for proteins enhancing proteolytic reactions, cell apoptosis, including oocytes, which disrupt the positive action of activin and damage structural and functional state of mitochondria. A definite relationship was found between the level of anti-Müllerian hormone and rate of detection of a number of proteins, in particular protocadherin-2α, cystatin C, betaglycan, prostatic acid phosphatase, and dermicidin. Conclusion. The revealed changes in proteomic profile of the follicular fluid obviously play an important role in the molecular mechanisms that determine the effectiveness of assisted reproductive technologies; the identified differentially expressed proteins can serve as objective markers for predicting the outcomes of in vitro fertilisation.

The role of various factors affecting the endometrium in enhancing the effectiveness of assisted reproductive technology programs

2021 ◽  
Vol 1_2021 ◽  
pp. 28-34
Author(s):  
Gokhberg Ya.A. Gokhberg ◽  
Makarova N.P. Makarova ◽  
Babayan A.A. Babayan ◽  
Kalinina E.A. Kalinina ◽  
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Factors Affecting ◽  
Technology Programs

Efficiency of assisted reproductive technology programs in stimulated-cycle embryo transfer versus cryopreserved-thawed embryo transfer

2016 ◽  
Vol 6_2016 ◽  
pp. 11-17
Author(s):  
Naimi M.S. Naimi ◽  
Kalinina E.A. Kalinina ◽  
Donnikov A.E. Donnikov ◽  
Alieva K.U. Alieva ◽  
Dudarova A.Kh. Dudarova ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Embryo Transfer ◽  
Reproductive Technology ◽  
Technology Programs ◽  
Thawed Embryo Transfer

Current embryo selection techniques in the implementation of assisted reproductive technology programs

2018 ◽  
Vol 2_2018 ◽  
pp. 13-18
Author(s):  
Korolkova A.I. Korolkova ◽  
Mishieva N.G. Mishieva ◽  
Burmenskaya O.V. Burmenskaya ◽  
Ekimov A.N. Ekimov ◽  
Abubakirov A.N. Abubakirov ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Embryo Selection ◽  
Technology Programs

Features of reproductive function realization in women with infertility and HIV infection in assisted reproductive technology programs

2017 ◽  
Vol 10_2017 ◽  
pp. 70-77
Author(s):  
Mityurina E.V. Mityurina ◽  
Perminova S.G. Perminova ◽  
Selimova F.N. Selimova ◽  
Kozyrina N.V. Kozyrina ◽  
Abubakirov A.N. Abubakirov ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Assisted Reproductive Technology ◽  
Reproductive Function ◽  
Reproductive Technology ◽  
Technology Programs

Use of cryopreserved embryos in assisted reproductive technology programs

2020 ◽  
Vol 4_2020 ◽  
pp. 195-200
Author(s):  
Petrosyan Ya.A. Petrosyan ◽  
Frolova A.M. Frolova ◽  
Syrkasheva A.G. Syrkasheva ◽  
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Technology Programs ◽  
Cryopreserved Embryos

Obstetric and neonatal outcomes of assisted reproductive technology programs using donor oocytes

2020 ◽  
Vol 4_2020 ◽  
pp. 31-36
Author(s):  
Mamedova T.R. Mamedova ◽  
Syrkasheva A.G. Syrkasheva ◽  
Dolgushina N.V. Dolgushina ◽  
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Neonatal Outcomes ◽  
Technology Programs ◽  
Donor Oocytes
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