The role of various factors affecting the endometrium in enhancing the effectiveness of assisted reproductive technology programs

2021 ◽  
Vol 1_2021 ◽  
pp. 28-34
Author(s):  
Gokhberg Ya.A. Gokhberg ◽  
Makarova N.P. Makarova ◽  
Babayan A.A. Babayan ◽  
Kalinina E.A. Kalinina ◽  
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Factors Affecting ◽  
Technology Programs

Role of preimplantation genetic screening in enhancing the effectiveness of assisted reproductive technology programs in late reproductive-aged patients

2018 ◽  
Vol 4_2018 ◽  
pp. 78-84 ◽  
Author(s):  
Beik E.P. Beik ◽  
Korotchenko O.E. Korotchenko ◽  
Gvozdeva A.D. Gvozdeva ◽  
Syrkasheva A.G. Syrkasheva ◽  
Dolgushina N.V. Dolgushina ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Genetic Screening ◽  
Preimplantation Genetic Screening ◽  
Reproductive Technology ◽  
Aged Patients ◽  
Technology Programs

Role of pronase hatching in enhancing the effectiveness of assisted reproductive technology programs

2018 ◽  
Vol 3_2018 ◽  
pp. 70-75 ◽  
Author(s):  
Dolgushina N.V. Dolgushina ◽  
Ibragimova E.O. Ibragimova ◽  
Romanov A.Yu. Romanov ◽  
Makarova N.P. Makarova ◽  
Dovgan A.A. Dovgan ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Technology Programs

The role of adipokines and gene regulators adipokines in the effectiveness of assisted reproductive technology programs in overweight patients

2017 ◽  
Vol 2_2017 ◽  
pp. 71-78 ◽  
Author(s):  
Dolgushina N.V. Dolgushina ◽  
Donnikov A.E. Donnikov ◽  
Vyssokikh M.Yu. Vyssokikh ◽  
Desiatkova N.V. Desiatkova N ◽  
Suhanova Yu.A. Suhanova ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Technology Programs

scholarly journals ROLE OF MALE INFERTILITY IN ASSISTED REPRODUCTIVE TECHNOLOGY PROGRAMS (A LITERATURE REVIEW)

2017 ◽  
Vol 18 (3) ◽  
pp. 28-36
Author(s):  
S. I. Gamidov ◽  
R. I. Ovchinnikov ◽  
A. Yu. Popova ◽  
N. P. Naumov ◽  
N. G. Gasanov
Keyword(s):  
Literature Review ◽  
Male Infertility ◽  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Technology Programs

The role of inflammatory cytokines in the pathogenesis of premature labor in multiple pregnancy as a result of ART

2016 ◽  
pp. 73-76
Author(s):  
B.M. Ventskivskiy ◽  
◽  
I.V. Poladych ◽  
S.O. Avramenko ◽  
◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Inflammatory Cytokines ◽  
Proinflammatory Cytokines ◽  
Local Level ◽  
Multiple Pregnancy ◽  
Reproductive Technology ◽  
System Level ◽  
Premature Labor ◽  
Pro Inflammatory Cytokines

In recent years there has been an increase in the frequency of multiple pregnancies and the associated perinatal losses. It is a result of multiple pregnancy in ART refers to a high-risk gestation, at which premature births occur in 2 times more often than in singleton pregnancies. The objective: to determine the role of pro-inflammatory cytokines in the pathogenesis of premature labor in multiple pregnancy, as a result of assisted reproductive technology. Patients and methods. to determine the pro-inflammatory cytokines that all pregnant with bagtopliddyam held immunosorbent assay, defined concentrations of interleukin (IL) in serum and cervical mucus. Results. The analysis of the levels of pro-inflammatory cytokines (IL-1, IL-8) in the test environment, found high concentrations in the surveyed women with multiple pregnancy, due to the use of ART, compared with spontaneous multiple and singleton pregnancy. Increased concentration of proinflammatory cytokines in patients with multiple pregnancy by ART is associated with their synthesis at the system level, it stimulated foci of inflammation in the female genitals and extragenital localization. This correlates with the clinical data and statistical analysis, patients with multiple pregnancy as a result of ART had weighed infectious-inflammatory history. Conclusion. The study showed that elevated levels of proinflammatory cytokines in the systemic and local level in patients with multiple pregnancy due to ART, typical for women with miscarriage, because of the physiological course of pregnancy characterized by the predominance of anti-inflammatory cytokines that prevent rejection of the fetus as a foreign factor. Based on the data obtained proved the role of systemic inflammatory factors in the genesis of preterm labor in women with a multiple pregnancy, as a result of assisted reproductive technology. Key words: multiple pregnancy, assisted reproductive technology, premature birth, interleukine-1, interleukine-8.

scholarly journals The Potential Applications of Peroxisome Proliferator-Activated ReceptorδLigands in Assisted Reproductive Technology

PPAR Research ◽  
2008 ◽  
Vol 2008 ◽  
pp. 1-6 ◽  
Author(s):  
Jaou-Chen Huang
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Function ◽  
Reproductive Technology ◽  
Embryonic Cell ◽  
Preimplantation Embryos ◽  
Peroxisome Proliferator ◽  
Peroxisome Proliferator Activated Receptor ◽  
Potential Applications ◽  
And Function

Peroxisome proliferator-activated receptorδ(PPARδ, also known as PPARβ) has ubiquitous distribution and extensive biological functions. The reproductive function of PPARδwas first revealed in the uterus at the implantation site. Since then, PPARδand its ligand have been discovered in all reproductive tissues, including the gametes and the preimplantation embryos. PPARδin preimplantation embryos is normally activated by oviduct-derived PPARδligand. PPARδactivation is associated with an increase in embryonic cell proliferation and a decrease in programmed cell death (apoptosis). On the other hand, the role of PPARδand its ligand in gamete formation and function is less well understood. This review will summarize the reproductive functions of PPARδand project its potential applications in assisted reproductive technology.

scholarly journals Role of autoantibodies in infertility, miscarriage, and assisted reproductive technology outcomes

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Ming-Qing Li ◽  
Hui-Hui Shen ◽  
Zhen-Zhen Lai ◽  
Hui-Li Yang ◽  
Jia-Wei Shi
Keyword(s):  
Assisted Reproductive Technology ◽  
Reproductive Technology

scholarly journals Significance of disorders of proteomic profile of follicular fluid for predicting the effectiveness of in vitro fertilisation in women with infertility

2018 ◽  
Vol 99 (3) ◽  
pp. 496-503
Author(s):  
O S Zolotykh ◽  
S V Lomteva ◽  
K Yu Sagamonova
Keyword(s):  
Assisted Reproductive Technology ◽  
Follicular Fluid ◽  
Molecular Mechanisms ◽  
Reproductive Technologies ◽  
Reproductive Technology ◽  
In Vitro Fertilisation ◽  
Proteomic Profile ◽  
Technology Programs ◽  
Group 2

Aim. To study the proteomic profile of follicular fluid in patients with infertility in assisted reproductive technology programs. Methods. The study included women with infertility included in assisted reproductive technology programs: 15 women who had in vitro fertilisation which resulted in pregnancy (group 1) and 16 women with a negative result of this program (group 2). Fractionation of the follicular fluid samples was performed using the sets of special magnetic beads. Proteomic profiling was performed by tandem MALDI-mass-spectrometry. The anti-Müllerian hormone level was measured by ELISA. Results. The study revealed differences in the detectability of follicular fluid proteins with different regulatory properties in patients of groups 1 and 2. With the negative outcome of in vitro fertilisation, expression of a number of proteins involved in the processes of folliculogenesis, ovulation, selection of the dominant follicle, as well as proteins necessary for the development of the zygote and blastula was reduced in females' follicular fluid. Increased expression in women from group 2 was registered for proteins enhancing proteolytic reactions, cell apoptosis, including oocytes, which disrupt the positive action of activin and damage structural and functional state of mitochondria. A definite relationship was found between the level of anti-Müllerian hormone and rate of detection of a number of proteins, in particular protocadherin-2α, cystatin C, betaglycan, prostatic acid phosphatase, and dermicidin. Conclusion. The revealed changes in proteomic profile of the follicular fluid obviously play an important role in the molecular mechanisms that determine the effectiveness of assisted reproductive technologies; the identified differentially expressed proteins can serve as objective markers for predicting the outcomes of in vitro fertilisation.

Sign in / Sign up

Export Citation Format

Share Document