Opportunities for antimicrobial therapy of diseases accompanied by pathological discharge from the genital tract: results of the multicenter observational Prospectus program

Neisseria gonorrhoeae is a Gram-negative, intracellular diplococcus that is transmitted by direct inoculation of infected secretion from one mucosa to another. It primarily colonizes the columnar epithelium of lower genital tract, only occasionally spreading to the upper genital tract or causing systemic disease. Oropharyngeal and rectal infections are common in men who have sex with men but also occur in women. N. gonorrhoeae is almost exclusively transmitted by sexual activity. Oropharyngeal and rectal infections usually produce no symptoms; disseminated gonococcal infection is a comparatively benign bacteraemia affecting joints (particularly shoulder and knee) and skin; traditionally more common in women than men. The gonococcus has adapted rapidly to prevalent antimicrobial usage, leading to resistance to all antibiotics used for treatment, notably penicillins, fluoroquinolones, macrolides, tetracycline, and cephalosporins. This development has resulted in major concerns internationally and the introduction of international and national action/response plans as well as dual antimicrobial therapy.

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Histochemical and Ultrastructural Studies of the Digestive Epithelium in a Gastropod Gametolytic Organ

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s143192760000252x ◽

1980 ◽

Vol 38 ◽

pp. 568-569

Author(s):

R. L. Reeder ◽

S. H. Rogers ◽

W. A. Shannon

Keyword(s):

Acid Phosphatase ◽

Genital Tract ◽

Reproductive Tract ◽

Ultrastructural Level ◽

Conclusive Evidence ◽

Digestive Organ ◽

Limited Information ◽

Ultrastructural Studies ◽

Morphological Studies

Numerous morphological studies have dealt with the spermatheca of pulmonate gastropods. This globular organ, which is attached to the female portion of the reproductive tract by a long duct in these monoecious animals, has had various functions ascribed to it. Recent histochemical demonstrations of deoxyribonuclease, ribonuclease, protease, and acid phosphatase have provided, however, conclusive evidence that it is a digestive organ for the degradation of superfluous sperm and genital tract secretions. Only limited information concerning the spermatheca is available at the ultrastructural level, a fact providing the stimulus for the present study of this organ in Sonorella santaritana, a desert mountain snail from Arizona.

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Endometrial cancer, vasculitis of the genital tract and occult temporal arteritis

Histopathology ◽

10.1046/j.1365-2559.2001.01072-2.x ◽

2001 ◽

Vol 38 (2) ◽

pp. 178-179 ◽

Cited By ~ 7

Author(s):

A Orbo ◽

A Steffensen

Keyword(s):

Endometrial Cancer ◽

Genital Tract ◽

Temporal Arteritis

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EFFECT OF HIGH DOSES OF OESTROGEN AND PROGESTERONE ON THE NORADRENALINE CONTENT OF THE SHORT ADRENERGIC NEURONS INNERVATING THE MALE GENITAL TRACT OF THE RAT

Acta Endocrinologica ◽

10.1530/acta.0.0640459 ◽

1970 ◽

Vol 64 (3) ◽

pp. 459-465 ◽

Cited By ~ 5

Author(s):

Ch. Owman ◽

N.-O. Sjöberg ◽

N. O. Sjöstrand ◽

G. Swedin

Keyword(s):

Genital Tract ◽

Reproductive Tract ◽

Female Genital Tract ◽

Total Content ◽

Prolonged Treatment ◽

Noradrenaline Content ◽

Adrenergic Neurons ◽

Short Adrenergic Neurons ◽

High Doses ◽

Male Genital

ABSTRACT The effect of prolonged treatment with high doses of oestrogen and/or progesterone on the amount of adrenergic transmitter in the short adrenergic neurons of the male reproductive tract of castrated rats has been studied by chemical determinations and histochemical demonstration of noradrenaline. Oestrogen, progesterone, or a combination of both, had no overt effect on the total content or on the concentration of noradrenaline in the male genital organs. The results are discussed in the light of recent findings that the content of the noradrenaline transmitter in the short adrenergic neurons to the female genital tract is markedly influenced by these female sex hormones.

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