Bioprocessing & biological challenges of large-scale red blood cell production from pluripotent stem cells: important factors to consider

2019 ◽  
Vol 5 (3) ◽  
pp. 483-504
Author(s):  
Jaichandran Sivalingam ◽  
Steve Kah-Weng Oh
Keyword(s):  
Stem Cells ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Pluripotent Stem Cells ◽  
Large Scale ◽  
Cell Production

Differentiation of Human Pluripotent Stem Cells for Red Blood Cell Production

2018 ◽  
pp. 47-62
Author(s):  
Mark C. Allenby ◽  
Susana Brito dos Santos ◽  
Nicki Panoskaltsis ◽  
Athanasios Mantalaris
Keyword(s):  
Stem Cells ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Pluripotent Stem Cells ◽  
Human Pluripotent Stem Cells ◽  
Cell Production

scholarly journals Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells

2016 ◽  
Vol 18 (1) ◽  
pp. 73-78 ◽  
Author(s):  
Felix C. Giani ◽  
Claudia Fiorini ◽  
Aoi Wakabayashi ◽  
Leif S. Ludwig ◽  
Rany M. Salem ◽  
...  
Keyword(s):  
Stem Cells ◽  
Genetic Variation ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Human Genetic Variation ◽  
Cell Production

Red blood cell generation from human induced pluripotent stem cells of different donor cell type origin

2013 ◽  
Vol 41 (8) ◽  
pp. S27
Author(s):  
Isabel Dorn ◽  
Katharina Klich ◽  
Martina Radstaak ◽  
Katherina Psathaki ◽  
Marcos Arauzo-Bravo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Blood Cell ◽  
Induced Pluripotent Stem Cells ◽  
Red Blood Cell ◽  
Pluripotent Stem Cells ◽  
Donor Cell ◽  
Cell Generation ◽  
Cell Type ◽  
Induced Pluripotent ◽  
Donor Cell Type

Superior Red Blood Cell Generation from Human Pluripotent Stem Cells Through a Novel Microcarrier-Based Embryoid Body Platform

2016 ◽  
Vol 22 (8) ◽  
pp. 765-780 ◽  
Author(s):  
Jaichandran Sivalingam ◽  
Alan Tin-Lun Lam ◽  
Hong Yu Chen ◽  
Bin Xia Yang ◽  
Allen Kuan-Liang Chen ◽  
...  
Keyword(s):  
Stem Cells ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Pluripotent Stem Cells ◽  
Embryoid Body ◽  
Human Pluripotent Stem Cells ◽  
Cell Generation

scholarly journals Study of RBC Histograms and Its Correlation with Etiopathogenesis and Other Parameters in Various Anemias

2021 ◽  
pp. 66-82
Author(s):  
A. P. Gokula Kannan ◽  
R. Govindarajan ◽  
J. Thanka
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Pluripotent Stem Cells ◽  
Morphological Features ◽  
Peripheral Smear ◽  
Smear Examination ◽  
Cytoplasmic Rna ◽  
Different Types

The pluripotent stem cells which are present in the bone marrow renew by its own and differentiate into mature cells. These stem cells undergo division by the presence of erythropoietin, where the nucleus is extruded out from the cell during the end of differentiation, thereby retaining cytoplasmic RNA to form a reticulocyte. The reticulocyte i s a precursor to red blood cell and on losing the RNA it matures into a Red Blood Cell. The present study aimed to analyze the correlation between the automated histogram patterns along with morphological features of RBC‘s prepared from peripheral smear examination in different types of anemia. viz., MCV, MCH, MCHC & RWD- CV.

scholarly journals Red blood cell generation from human induced pluripotent stem cells: perspectives for transfusion medicine

Haematologica ◽  
2010 ◽  
Vol 95 (10) ◽  
pp. 1651-1659 ◽  
Author(s):  
H. Lapillonne ◽  
L. Kobari ◽  
C. Mazurier ◽  
P. Tropel ◽  
M.-C. Giarratana ◽  
...  
Keyword(s):  
Stem Cells ◽  
Blood Cell ◽  
Induced Pluripotent Stem Cells ◽  
Red Blood Cell ◽  
Pluripotent Stem Cells ◽  
Cell Generation ◽  
Transfusion Medicine ◽  
Induced Pluripotent

scholarly journals PS1235 RED BLOOD CELL GENERATION FROM HUMAN INDUCED PLURIPOTENT STEM CELLS

HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 562
Author(s):  
E. Varga ◽  
M. Hansen ◽  
S. Heshusius ◽  
P. Burger ◽  
T. Wust ◽  
...  
Keyword(s):  
Stem Cells ◽  
Blood Cell ◽  
Induced Pluripotent Stem Cells ◽  
Red Blood Cell ◽  
Pluripotent Stem Cells ◽  
Cell Generation ◽  
Induced Pluripotent

Superior Red Blood Cell Generation From Human Pluripotent Stem Cells via a Novel Microcarrier Based Embryoid Body Platform

Cytotherapy ◽  
2016 ◽  
Vol 18 (6) ◽  
pp. S41-S42
Author(s):  
J. Sivalingam ◽  
E. Lee ◽  
A. Lam ◽  
A. Chen ◽  
S. Reuveny ◽  
...  
Keyword(s):  
Stem Cells ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Pluripotent Stem Cells ◽  
Embryoid Body ◽  
Human Pluripotent Stem Cells ◽  
Cell Generation
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