Physical and functional measures predicting long-term mortality in community-dwelling older adults: a comparative evaluation in the Singapore Longitudinal Ageing Study

Dairy products (DP) are part of a food group that may contribute to the prevention of physical frailty. We aimed to investigate DP exposure, including total DP, milk, fresh DP and cheese, and their cross-sectional and prospective associations with physical frailty in community-dwelling older adults. The cross-sectional analysis was carried out on 1490 participants from the Three-City Bordeaux cohort. The 10-year frailty risk was examined in 823 initially non-frail participants. A food frequency questionnaire was used to assess DP exposure. Physical frailty was defined as the presence of at least 3 out of 5 criteria of the frailty phenotype: weight loss, exhaustion, slowness, weakness, and low physical activity. Among others, diet quality and protein intake were considered as confounders. The baseline mean age of participants was 74.1 y and 61% were females. Frailty prevalence and incidence were 4.2% and 18.2%, respectively. No significant associations were observed between consumption of total DP or DP sub-types and frailty prevalence or incidence (OR = 1.40, 95%CI 0.65–3.01 and OR = 1.75, 95%CI 0.42–1.32, for a total DP consumption >4 times/d, respectively). Despite the absence of beneficial associations of higher DP consumption on frailty, older adults are encouraged to follow the national recommendations regarding DP.

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Long-term effects of mnemonic training in community-dwelling older adults

Journal of Psychiatric Research ◽

10.1016/j.jpsychires.2006.04.010 ◽

2007 ◽

Vol 41 (7) ◽

pp. 585-590 ◽

Cited By ~ 25

Author(s):

Ruth O’Hara ◽

John O. Brooks ◽

Leah Friedman ◽

Carmen M. Schröder ◽

Kevin S. Morgan ◽

...

Keyword(s):

Older Adults ◽

Community Dwelling ◽

Long Term Effects ◽

Community Dwelling Older Adults

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Health condition and physical function as predictors of adherence in long-term strength and balance training among community-dwelling older adults

Archives of Gerontology and Geriatrics ◽

10.1016/j.archger.2015.06.016 ◽

2015 ◽

Vol 61 (3) ◽

pp. 452-457 ◽

Cited By ~ 11

Author(s):

Eeva Aartolahti ◽

Anna-Maija Tolppanen ◽

Eija Lönnroos ◽

Sirpa Hartikainen ◽

Arja Häkkinen

Keyword(s):

Older Adults ◽

Physical Function ◽

Balance Training ◽

Health Condition ◽

Community Dwelling ◽

Term Strength ◽

Community Dwelling Older Adults ◽

Predictors Of Adherence

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Long-Term Exposure to Air Pollutants and Cognitive Function in Taiwanese Community-Dwelling Older Adults: A Four-Year Cohort Study

Advances in Alzheimer’s Disease - Alzheimer’s Disease and Air Pollution ◽

10.3233/aiad210022 ◽

2021 ◽

Author(s):

Jen-Hau Chen ◽

Tsung-Yu Kuo ◽

Hwa-Lung Yu ◽

Charlene Wu ◽

Su-Ling Yeh ◽

...

Keyword(s):

Older Adults ◽

Cohort Study ◽

Executive Function ◽

Verbal Fluency ◽

Air Pollutants ◽

Community Dwelling ◽

High Concentrations ◽

High Level ◽

Community Dwelling Older Adults

Background: Previous studies have assessed limited cognitive domains with relatively short exposure to air pollutants, and studies in Asia are limited. Objective: This study aims to explore the association between long-term exposure to air pollutants and cognition in community-dwelling older adults. Methods: This four-year prospective cohort study recruited 605 older adults at baseline (2011–2013) and 360 participants remained at four-year follow-up. Global and domain-specific cognition were assessed biennially. Data on PM2.5 (particulate matter ≤ 2.5 μm diameter, 2005–2015), PM10 (1993–2015), and nitrogen dioxide (NO2, 1993–2015) were obtained from Taiwan Environmental Protection Administration (TEPA). Bayesian Maximum Entropy was utilized to estimate the spatiotemporal distribution of levels of these pollutants. Results: Exposure to high-level PM2.5 (>29.98 μg/m3) was associated with an increased risk of global cognitive impairment (adjusted odds ratio = 4.56; β = −0.60). High-level PMcoarse exposure (>26.50 μg/m3) was associated with poor verbal fluency (β = −0.19). High-level PM10 exposure (>51.20 μg/m3) was associated with poor executive function (β = −0.24). Medium-level NO2 exposure (>28.62 ppb) was associated with better verbal fluency (β = 0.12). Co-exposure to high concentrations of PM2.5, PMcoarse or PM10 and high concentration of NO2 were associated with poor verbal fluency (PM2.5 and NO2: β = −0.17; PMcoarse and NO2: β = −0.23; PM10 and NO2: β = −0.21) and poor executive function (PM10 and NO2: β = −0.16). These associations became more evident in women, apolipoprotein ε4 non-carriers, and those with education > 12 years. Conclusion: Long-term exposure to PM2.5 (higher than TEPA guidelines), PM10 (lower than TEPA guidelines) or co-exposure to PMx and NO2 were associated with poor global, verbal fluency, and executive function over 4 years.

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Bed occupancy measurements using under mattress pressure sensors for long term monitoring of community-dwelling older adults

2013 IEEE International Symposium on Medical Measurements and Applications (MeMeA) ◽

10.1109/memea.2013.6549721 ◽

2013 ◽

Cited By ~ 11

Author(s):

M. Taylor ◽

T. Grant ◽

F. Knoefel ◽

R. Goubran

Keyword(s):

Older Adults ◽

Pressure Sensors ◽

Community Dwelling ◽

Bed Occupancy ◽

Long Term Monitoring ◽

Community Dwelling Older Adults ◽

Term Monitoring

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Long-Term Exposure to Air Pollutants and Cognitive Function in Taiwanese Community-Dwelling Older Adults: A Four-Year Cohort Study

Journal of Alzheimer s Disease ◽

10.3233/jad-200614 ◽

2020 ◽

Vol 78 (4) ◽

pp. 1585-1600

Author(s):

Jen-Hau Chen ◽

Tsung-Yu Kuo ◽

Hwa-Lung Yu ◽

Charlene Wu ◽

Su-Ling Yeh ◽

...

Keyword(s):

Older Adults ◽

Cohort Study ◽

Executive Function ◽

Verbal Fluency ◽

Air Pollutants ◽

Community Dwelling ◽

Short Exposure ◽

High Level ◽

Community Dwelling Older Adults

Background: Previous studies have assessed limited cognitive domains with relatively short exposure to air pollutants, and studies in Asia are limited. Objective: This study aims to explore the association between long-term exposure to air pollutants and cognition in community-dwelling older adults. Methods: This four-year prospective cohort study recruited 605 older adults at baseline (2011–2013) and 360 participants remained at four-year follow-up. Global and domain-specific cognition were assessed biennially. Data on PM2.5 (particulate matter≤2.5μm diameter, 2005–2015), PM10 (1993–2015), and nitrogen dioxide (NO2, 1993–2015) were obtained from Taiwan Environmental Protection Administration (TEPA). Bayesian Maximum Entropy was utilized to estimate the spatiotemporal distribution of levels of these pollutants. Results: Exposure to high-level PM2.5 (>29.98μg/m3) was associated with an increased risk of global cognitive impairment (adjusted odds ratio = 4.56; β= –0.60). High-level PMcoarse exposure (>26.50μg/m3) was associated with poor verbal fluency (β= –0.19). High-level PM10 exposure (>51.20μg/m3) was associated with poor executive function (β= –0.24). Medium-level NO2 exposure (>28.62 ppb) was associated with better verbal fluency (β= 0.12). Co-exposure to high concentrations of PM2.5, PMcoarse or PM10 and high concentration of NO2 were associated with poor verbal fluency (PM2.5 and NO2: β= –0.17; PMcoarse and NO2: β= –0.23; PM10 and NO2: β= –0.21) and poor executive function (PM10 and NO2: β= –0.16). These associations became more evident in women, apolipoprotein ɛ4 non-carriers, and those with education > 12 years. Conclusion: Long-term exposure to PM2.5 (higher than TEPA guidelines), PM10 (lower than TEPA guidelines) or co-exposure to PMx and NO2 were associated with poor global, verbal fluency, and executive function over 4 years.

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Long‐Term Effects of Three Multicomponent Exercise Interventions on Physical Performance and Fall‐Related Psychological Outcomes in Community‐Dwelling Older Adults: A Randomized Controlled Trial

Journal of the American Geriatrics Society ◽

10.1111/j.1532-5415.2011.03859.x ◽

2012 ◽

Vol 60 (3) ◽

pp. 437-446 ◽

Cited By ~ 99

Author(s):

Ellen Freiberger ◽

Lothar Häberle ◽

Waneen W. Spirduso ◽

G. A. Rixt Zijlstra

Keyword(s):

Older Adults ◽

Randomized Controlled Trial ◽

Physical Performance ◽

Controlled Trial ◽

Community Dwelling ◽

Long Term Effects ◽

Exercise Interventions ◽

Randomized Controlled ◽

Community Dwelling Older Adults

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Association Between Urate-Lowering Therapies and Cognitive Decline in Community-Dwelling Older Adults: A Post-Hoc Analysis of the MAPT Study.

10.21203/rs.3.rs-699328/v1 ◽

2021 ◽

Author(s):

Luc MOLET-BENHAMOU ◽

Kelly VIRECOULON GIUDICI ◽

Philipe BARRETO ◽

Yves ROLLAND

Keyword(s):

Older Adults ◽

Cognitive Decline ◽

Controlled Trial ◽

Community Dwelling ◽

Composite Score ◽

Cognitive Score ◽

Using Data ◽

Community Dwelling Older Adults

Abstract Introduction Long-term use of urate-lowering therapies (ULT) may reduce inflammaging and thus prevent cognitive decline during aging. This article examined the association between long-term use of ULT and cognitive decline among community-dwelling older adults with spontaneous memory complaints. Material and methods We performed a secondary observational analysis using data of 1,673 participants ≥ 70 years old from the Multidomain Alzheimer Preventive Trial (MAPT Study), a randomized controlled trial assessing the effect of a multidomain intervention, the administration of polyunsaturated fatty acids (PUFA), both, or placebo on cognitive decline. We compared cognitive decline during the 5-year follow-up between three groups according to ULT use: participants treated with ULT during at least 75% of the study period (PT ≥ 75; n = 51), less than 75% (PT < 75; n = 31), and non-treated participants (PNT; n = 1,591). Cognitive function (measured by a composite score) was assessed at baseline, 6 months and every year for 5 years. Linear mixed models were performed and adjusted for age, sex, body mass index (BMI), diagnosis of arterial hypertension or diabetes, baseline composite cognitive score, and MAPT intervention groups. Results After the 5-year follow-up, only non-treated participants presented a significant decline in the cognitive composite score (mean change − 0.173, 95%CI -0.212 to -0.135; p < 0.0001). However, there were no differences in change of the composite cognitive score between groups (adjusted between-group difference for PNT vs. PT < 75: 0.089, 95%CI -0.160 to 0.338, p = 0.484; PNT vs. PT ≥ 75: 0.174, 95%CI -0.042 to 0.391, p = 0.115). Conclusion Use of ULT was not associated with reduced cognitive decline over a 5-year follow-up among community-dwelling older adults at risk of dementia.

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