scholarly journals HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs

Oncotarget ◽  
2016 ◽  
Vol 8 (1) ◽  
pp. 1247-1261 ◽  
Author(s):  
Xujun He ◽  
Zhengchuang Liu ◽  
Yingjie Xia ◽  
Ji Xu ◽  
Guocai Lv ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cell Proliferation ◽  
Cancer Patients ◽  
Poor Prognosis ◽  
Gastric Cancer Patients

Severe Loss of Visceral Fat and Skeletal Muscle After Chemotherapy Predict Poor Prognosis in Metastatic Gastric Cancer Patients Without Gastrectomy

2019 ◽  
Author(s):  
Wanjing Feng ◽  
Mingzhu Huang ◽  
Xiaoying Zhao ◽  
Siyuan Chen ◽  
Chenchen Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Skeletal Muscle ◽  
Cancer Patients ◽  
Visceral Fat ◽  
Poor Prognosis ◽  
Metastatic Gastric Cancer ◽  
Severe Loss ◽  
Gastric Cancer Patients

scholarly journals Low FAT4 expression is associated with a poor prognosis in gastric cancer patients

Oncotarget ◽  
2017 ◽  
Vol 9 (4) ◽  
pp. 5137-5154 ◽  
Author(s):  
Xiaoting Jiang ◽  
Zhengchuang Liu ◽  
Yingjie Xia ◽  
Jungang Luo ◽  
Ji Xu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Poor Prognosis ◽  
Gastric Cancer Patients

scholarly journals LAPTM4B-35, a Cancer-Related Gene, Is Associated with Poor Prognosis in TNM Stages I-III Gastric Cancer Patients

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0121559 ◽  
Author(s):  
Xiaojing Cheng ◽  
Zhixue Zheng ◽  
Zhaode Bu ◽  
Xiaojiang Wu ◽  
Lianhai Zhang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Poor Prognosis ◽  
Related Gene ◽  
Cancer Related Gene ◽  
Gastric Cancer Patients

scholarly journals The Rhesus D-negative phenotype is an independent predictor of poor prognosis in curatively (RO) resected gastric cancer patients

1997 ◽  
Vol 75 (9) ◽  
pp. 1291-1294 ◽  
Author(s):  
B Mayer ◽  
W Schraut ◽  
I Funke ◽  
KW Jauch ◽  
W Mempel ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Poor Prognosis ◽  
Independent Predictor ◽  
Gastric Cancer Patients ◽  
Resected Gastric Cancer ◽  
Negative Phenotype

Activated Pak4 expression correlates with poor prognosis in human gastric cancer patients

Tumor Biology ◽  
2015 ◽  
Vol 36 (12) ◽  
pp. 9431-9436 ◽  
Author(s):  
Danni Li ◽  
Ye Zhang ◽  
Zhi Li ◽  
Ximing Wang ◽  
Xiujuan Qu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Poor Prognosis ◽  
Human Gastric Cancer ◽  
Gastric Cancer Patients

TKTL1 and p63 are biomarkers for the poor prognosis of gastric cancer patients

2015 ◽  
Vol 15 (5) ◽  
pp. 591-597 ◽  
Author(s):  
Yan Song ◽  
Dan Liu ◽  
Guoping He
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Poor Prognosis ◽  
The Poor ◽  
Gastric Cancer Patients

scholarly journals High expression of NDRG3 correlates with poor prognosis in gastric cancer patients

2021 ◽  
Author(s):  
Yun Liu ◽  
Jinxuan Xia ◽  
Yong Zhou ◽  
Shihe Shao
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Poor Prognosis ◽  
High Expression ◽  
Gastric Cancer Patients

scholarly journals miR-491 inhibits BGC-823 cell migration via targeting HMGA2

2019 ◽  
Vol 34 (4) ◽  
pp. 364-372 ◽  
Author(s):  
Zhigang Liu ◽  
Yun Lü ◽  
Qiuyu Jiang ◽  
Yang Yang ◽  
Chengxue Dang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cell Proliferation ◽  
Cancer Patients ◽  
Luciferase Reporter ◽  
Luciferase Reporter Gene ◽  
Cancer Proliferation ◽  
Cell Proliferation And Migration ◽  
And Migration ◽  
Gastric Cancer Patients ◽  
Proliferation And Migration

Purpose: miR-491 functions as a tumor suppressor in several types of cancer. However, its function and mechanism in gastric cancer proliferation and metastasis have not been well defined. The aim of this study was to explore the role and regulatory mechanism of miR-491 in cell proliferation and migration in gastric cancer. Methods: Quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) was used to detect the expression pattern of miR-491 in gastric cancer tissues. miR-491 overexpression vector, miR-491 inhibitor, and siHMGA2 were used; and MTT, wound healing, and transwell assays were employed to examine proliferation and migration for BGC-823 cells. A dual-luciferase reporter gene was used to measure the target relationship between miR-491 and HMGA2. Results: Most gastric cancer patients exhibit decreased miR-491 expression. miR-491 overexpression inhibited cell proliferation and migration, whereas miR-491 inhibitor treatment produced the opposite effect. Mechanistically, HMGA2 was identified as a direct target of miR-491. Moreover, HMGA2 knockdown inhibited cell proliferation and migration, which was similar to the effect of miR-491 overexpression. HMGA2 was decreased after transfection of the miR-491 vector and increased after transfection of the miR-491 inhibitor. Conclusion: Our results suggest that miR-491 suppressed cell proliferation and cell motility in gastric cancer by targeting HMGA2. Silencing HMGA2 produced a similar effect to miR-491 overexpression on cell proliferation and migration. miR-491/HMGA2 signaling may be a potential therapeutic target for gastric cancer patients with decreased miR-491 expression.

scholarly journals Low expression of transferrin receptor 2 predict poor prognosis in gastric cancer patients

2020 ◽  
Vol 36 (12) ◽  
pp. 1014-1020
Author(s):  
Qian‐Fu Zhao ◽  
Jun Ji ◽  
Qu Cai ◽  
Chao Wang ◽  
Min Shi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Transferrin Receptor ◽  
Poor Prognosis ◽  
Gastric Cancer Patients ◽  
Low Expression ◽  
Transferrin Receptor 2

WASF3expression correlates with poor prognosis in gastric cancer patients

2019 ◽  
Vol 15 (14) ◽  
pp. 1605-1615 ◽  
Author(s):  
Yanli Nie ◽  
Sheng Hu ◽  
Sanhe Liu ◽  
Na Fang ◽  
Fang Guo ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Patients ◽  
Poor Prognosis ◽  
Gastric Cancer Patients
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