Mimicking the BIM BH3 domain overcomes resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

Bh3 Domain ◽

Adjuvant EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer: still an investigational approach

Translational Lung Cancer Research ◽

10.21037/tlcr.2019.09.02 ◽

2019 ◽

Vol 8 (S4) ◽

pp. S387-S390

Author(s):

Jacek Jassem

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

Feasibility of rebiopsy and sequential treatment of EGFR tyrosine kinase inhibitors in real world patients with EGFR mutant non-small cell lung cancer

Annals of Oncology ◽

10.1093/annonc/mdz437.018 ◽

2019 ◽

Vol 30 ◽

pp. ix166

Author(s):

H. Ahn ◽

Y. Kim ◽

E.Y. Kim ◽

K.W. Kim ◽

K.H. Sung ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Real World ◽

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

Use of adjuvant EGFR tyrosine kinase inhibitors in early stage EGFR-mutant non-small cell lung cancer: is the evidence strong enough?

Journal of Thoracic Disease ◽

10.21037/jtd-20-1817 ◽

2020 ◽

Vol 12 (9) ◽

pp. 5042-5045

Author(s):

Christopher Lemmon ◽

Nathan A. Pennell

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Kinase Inhibitors ◽

Early Stage ◽

Small Cell ◽

Small Cell Lung ◽

Effect of simvastatin on the resistance to EGFR tyrosine kinase inhibitors in a non-small cell lung cancer with the T790M mutation of EGFR

Experimental Cell Research ◽

10.1016/j.yexcr.2014.02.026 ◽

2014 ◽

Vol 323 (2) ◽

pp. 288-296 ◽

Cited By ~ 26

Author(s):

Ki-Eun Hwang ◽

Su-Jin Kwon ◽

Young-Suk Kim ◽

Do-Sim Park ◽

Byoung-Ryun Kim ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

T790m Mutation ◽

Targeting non-small cell lung cancer with small-molecule EGFR tyrosine kinase inhibitors

Drug Discovery Today ◽

10.1016/j.drudis.2017.10.004 ◽

2018 ◽

Vol 23 (3) ◽

pp. 745-753 ◽

Cited By ~ 49

Author(s):

Mahaveer Singh ◽

Hemant R. Jadhav

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Small Molecule ◽

Cell Lung Cancer ◽

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

BREED based de novo hybridization approach: generating novel T790M/C797S-EGFR tyrosine kinase inhibitors to overcome the problem of mutation and resistance in non small cell lung cancer (NSCLC)

Journal of Biomolecular Structure and Dynamics ◽

10.1080/07391102.2020.1754918 ◽

2020 ◽

pp. 1-19

Author(s):

Harun M. Patel ◽

Matin Shaikh ◽

Iqrar Ahmad ◽

Deepak Lokwani ◽

Sanjay J. Surana

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitors ◽

De Novo ◽

Small Cell ◽

Small Cell Lung ◽

Targeting Resistance in Egfr-Mutant Non-Small Cell Lung Cancer (Nsclc): Preclinical Evidence Supporting the Combination of Egfr Tyrosine Kinase Inhibitors (Tkis) Azd9291 and Gefitinib with Molecularly Targeted Agents and Immunotherapeutics

Annals of Oncology ◽

10.1093/annonc/mdu331.26 ◽

2014 ◽

Vol 25 ◽

pp. iv155 ◽

Cited By ~ 1

Author(s):

D. Cross ◽

C. D'Cruz ◽

C. Eberlein ◽

P. Spitzler ◽

E. Ichihara ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Kinase Inhibitors ◽

Small Cell ◽

Targeted Agents ◽

Small Cell Lung ◽

Molecularly Targeted Agents ◽

P2.03-013 Uncommon Mutation Types of EGFR and Response to EGFR Tyrosine Kinase Inhibitors in Chinese Non-Small Cell Lung Cancer Patients

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2017.09.1264 ◽

2017 ◽

Vol 12 (11) ◽

pp. S2132

Author(s):

K. Chen ◽

X. Yu ◽

H. Wang ◽

Z. Huang ◽

Y. Xu ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Drug-Drug Interactions, Safety, and Pharmacokinetics of EGFR Tyrosine Kinase Inhibitors for the Treatment of Non–Small Cell Lung Cancer

Journal of the Advanced Practitioner in Oncology ◽

10.6004/jadpro.2018.9.2.5 ◽

2018 ◽

Vol 9 (2) ◽

Author(s):

Colleen R. Kucharczuk, DNP, CRNP ◽

Alex Ganetsky, PharmD, BCOP ◽

J. Michael Vozniak, PharmD, BCOP

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Drug Interactions ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

EGFR tyrosine kinase inhibitors in the treatment of advanced non-small cell lung cancer

Journal of Clinical Oncology ◽

10.1200/jco.2008.26.15_suppl.19117 ◽

2008 ◽

Vol 26 (15_suppl) ◽

pp. 19117-19117

Author(s):

D. M. Kowalski ◽

M. Krzakowski ◽

P. Jaskiewicz ◽

A. Janowicz-Zebrowska ◽

M. Glogowski

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitors ◽

Small Cell ◽

Small Cell Lung ◽

Egfr Tyrosine Kinase ◽