scholarly journals Ubiquitin carboxyl-terminal hydrolase isozyme L5 inhibits human glioma cell migration and invasion via downregulating SNRPF

Oncotarget ◽  
2017 ◽  
Vol 8 (69) ◽  
pp. 113635-113649 ◽  
Author(s):  
Jiafeng Ge ◽  
Weiwei Hu ◽  
Hui Zhou ◽  
Juan Yu ◽  
Chongran Sun ◽  
...  
Keyword(s):  
Cell Migration ◽  
Glioma Cell ◽  
Migration And Invasion ◽  
Human Glioma ◽  
Cell Migration And Invasion ◽  
Human Glioma Cell ◽  
Carboxyl Terminal ◽  
Glioma Cell Migration

scholarly journals EXTH-03. HUMAN GLIOMA CELL MIGRATION AND INVASION PROPERTIES ARE INHIBITED BY EXPOSURE TO TUMOR TREATING FIELDS (TTFIELDS) IN VITRO

2016 ◽  
Vol 18 (suppl_6) ◽  
pp. vi60-vi60
Author(s):  
Rosa Schneiderman ◽  
Anna Shteingauz ◽  
Moshe Giladi ◽  
Tali Voloshin ◽  
Yaara Porat ◽  
...  
Keyword(s):  
Cell Migration ◽  
Glioma Cell ◽  
Migration And Invasion ◽  
Human Glioma ◽  
Cell Migration And Invasion ◽  
Human Glioma Cell ◽  
Tumor Treating Fields ◽  
Glioma Cell Migration

scholarly journals Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation

2012 ◽  
Vol 23 (14) ◽  
pp. 2635-2644 ◽  
Author(s):  
Tao Tao ◽  
Chun Cheng ◽  
Yuhong Ji ◽  
Guangfei Xu ◽  
Jianguo Zhang ◽  
...  
Keyword(s):  
Cell Migration ◽  
Cell Lines ◽  
Glioma Cell ◽  
Tumor Necrosis Factor Receptor ◽  
Migration And Invasion ◽  
Human Glioma ◽  
Tissue Samples ◽  
Cell Migration And Invasion ◽  
Glioma Cell Migration

The Notch signaling regulator Numblike (Numbl) is expressed in the brain, but little is known regarding its role in the pathophysiology of glial cells. In this paper, we report that Numbl expression was down-regulated in high-grade human glioma tissue samples and glioblastoma cell lines. To investigate the role of Numbl in glioma migration and invasion, we generated human glioma cell lines in which Numbl was either overexpressed or depleted. Overexpression of Numbl suppressed, while elimination of Numbl promoted, the migration and invasion of glioma cells. Numbl inhibited glioma migration and invasion by dampening NF-κB activity. Furthermore, Numbl interacted directly with tumor necrosis factor receptor–associated factor 5 (TRAF5), which signals upstream and is required for the activation of NF-κB, and committed it to proteasomal degradation by promoting K48-linked polyubiquitination of TRAF5. In conclusion, our data suggest that Numbl negative regulates glioma cell migration and invasion by abrogating TRAF5-induced activation of NF-κB.

Downregulation of PAK5 inhibits glioma cell migration and invasion potentially through the PAK5-Egr1-MMP2 signaling pathway

2013 ◽  
Vol 31 (4) ◽  
pp. 234-241 ◽  
Author(s):  
Zheng-Xiang Han ◽  
Xiao-Xia Wang ◽  
Shang-Nuan Zhang ◽  
Jin-Xia Wu ◽  
He-ya Qian ◽  
...  
Keyword(s):  
Cell Migration ◽  
Signaling Pathway ◽  
Glioma Cell ◽  
Migration And Invasion ◽  
Cell Migration And Invasion ◽  
Glioma Cell Migration

scholarly journals Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor

Oncogene ◽  
2018 ◽  
Vol 38 (10) ◽  
pp. 1734-1750 ◽  
Author(s):  
J. P. Zepecki ◽  
K. M. Snyder ◽  
M. M. Moreno ◽  
E. Fajardo ◽  
A. Fiser ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Migration ◽  
Tumor Growth ◽  
Glioma Cell ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Migration

scholarly journals The phosphorylation of ephrin-B2 ligand promotes glioma cell migration and invasion

2009 ◽  
pp. NA-NA ◽  
Author(s):  
Mitsutoshi Nakada ◽  
Eric M. Anderson ◽  
Tim Demuth ◽  
Satoko Nakada ◽  
Linsey B. Reavie ◽  
...  
Keyword(s):  
Cell Migration ◽  
Glioma Cell ◽  
Migration And Invasion ◽  
Cell Migration And Invasion ◽  
Glioma Cell Migration

scholarly journals Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism

2005 ◽  
Vol 144 (8) ◽  
pp. 1032-1036 ◽  
Author(s):  
Angelo Vaccani ◽  
Paola Massi ◽  
Arianna Colombo ◽  
Tiziana Rubino ◽  
Daniela Parolaro
Keyword(s):  
Cell Migration ◽  
Glioma Cell ◽  
Cannabinoid Receptor ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Independent Mechanism ◽  
Glioma Cell Migration

scholarly journals TGF-β-induced miR10a/b expression promotes human glioma cell migration by targeting PTEN

2013 ◽  
Vol 8 (6) ◽  
pp. 1741-1746 ◽  
Author(s):  
SHIHAI LIU ◽  
JUNFENG SUN ◽  
QING LAN
Keyword(s):  
Cell Migration ◽  
Glioma Cell ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Migration

scholarly journals CSIG-35. A LOCALLY TRANSLATED Lck PATHWAY REGULATES HUMAN GLIOMA CELL MIGRATION, TUMOR GROWTH AND STEMNESS GENE EXPRESSION

2017 ◽  
Vol 19 (suppl_6) ◽  
pp. vi57-vi57
Author(s):  
John Zepecki ◽  
Kristin Snyder ◽  
Steven Toms ◽  
Atom Sarkar ◽  
Nikos Tapinos
Keyword(s):  
Gene Expression ◽  
Cell Migration ◽  
Tumor Growth ◽  
Glioma Cell ◽  
Human Glioma ◽  
Human Glioma Cell ◽  
Glioma Cell Migration
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