Endometrial cancer prevention - does bariatric surgery play a role?

Gineco eu ◽  
2017 ◽  
Vol 13 (1) ◽  
pp. 37-39
Author(s):  
Balescu I.
Keyword(s):  
Bariatric Surgery ◽  
Endometrial Cancer ◽  
Cancer Prevention

scholarly journals Cancer Risk After Bariatric Surgery in a Cohort Study from the Five Nordic Countries

2020 ◽  
Vol 30 (10) ◽  
pp. 3761-3767
Author(s):  
Wenjing Tao ◽  
Giola Santoni ◽  
My von Euler-Chelpin ◽  
Rickard Ljung ◽  
Elsebeth Lynge ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Endometrial Cancer ◽  
Cohort Study ◽  
Cancer Risk ◽  
Hodgkin Lymphoma ◽  
Cox Regression ◽  
Nordic Countries ◽  
Chronic Obstructive ◽  
Non Hodgkin Lymphoma ◽  
The Impact

Abstract Purpose Obesity increases the risk of several cancers, but the influence of bariatric surgery on the risk of individual obesity-related cancers is unclear. This study aimed to assess the impact of bariatric surgery on cancer risk in a multi-national setting. Materials and Methods This cohort study included all adults with an obesity diagnosis identified from national patient registries in all Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) from 1980 to 2012. Cancer risk in bariatric surgery patients was compared with non-operated patients with obesity. Multivariable Cox regression provided adjusted hazard ratios (HRs) with 95% confidence intervals (CIs). Age, sex, calendar year, country, length of follow-up, diabetes, chronic obstructive pulmonary disease and alcohol-related diseases were evaluated as confounders. Results Among 482,572 participants with obesity, 49,096 underwent bariatric surgery. Bariatric surgery was followed by a decreased overall cancer risk in women (HR 0.86, 95% CI 0.80–0.92), but not in men (HR 0.98, 95% CI 0.95–1.01). The risk reduction was observed only within the first five post-operative years. Among specific tumours, HRs decreased for breast cancer (HR 0.81, 95% CI 0.69–0.95), endometrial cancer (HR 0.69, 95% CI 0.56–0.84) and non-Hodgkin lymphoma (HR 0.64, 95% CI 0.42–0.97) in female bariatric surgery patients, while the risk of kidney cancer increased in both sexes (HR 1.44, 95% CI 1.13–1.84). Conclusion Bariatric surgery may decrease overall cancer risk in women within the first five years after surgery. This decrease may be explained by a decreased risk of breast and endometrial cancer and non-Hodgkin lymphoma in women.

Abstract P5-08-19: The risk of breast, ovarian and endometrial cancer in obese women submitted to bariatric surgery: A meta-analysis

2020 ◽  
Author(s):  
Beatriz Pércia Ishihara ◽  
Daniela Farah ◽  
Marcelo Cunio Machado Fonseca ◽  
Afonso Celso Pinto Nazário
Keyword(s):  
Bariatric Surgery ◽  
Endometrial Cancer ◽  
Meta Analysis ◽  
Obese Women

Disparities in the ameliorative effects of bariatric surgery on endometrial cancer risk biomarkers.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e13038-e13038
Author(s):  
Faina Linkov ◽  
Sharon Goughnour ◽  
Robert P. Edwards ◽  
Anna Lokshin ◽  
Ramesh Ramanathan ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Endometrial Cancer ◽  
Cancer Risk ◽  
Endometrial Cancer Risk ◽  
Risk Biomarkers

Levonorgestrel Intrauterine Device as an Endometrial Cancer Prevention Strategy in Obese Women

2016 ◽  
Vol 128 (4) ◽  
pp. 747-753 ◽  
Author(s):  
Joseph A. Dottino ◽  
Vic Hasselblad ◽  
Angeles Alvarez Secord ◽  
Evan R. Myers ◽  
Junzo Chino ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Cancer Prevention ◽  
Intrauterine Device ◽  
Prevention Strategy ◽  
Obese Women

Bariatric surgery reduces risk of endometrial cancer

2015 ◽  
Vol 11 (6) ◽  
pp. 1410 ◽  
Author(s):  
Sikarin Upala ◽  
Anawin Sanguankeo
Keyword(s):  
Bariatric Surgery ◽  
Endometrial Cancer
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