scholarly journals Fixed combination of beta adrenoblocker and calcium channel antagonist in hypertensive patients

2009 ◽  
Vol 15 (2) ◽  
pp. 116-120
Author(s):  
A. Panov

Combination antihypertensive therapy is supposed to be reasonable at first stages of the disease. The review summarizes the data on metoprolol succinate and felodipine effects as a combination medicine Logimax that due to its pharmacodynamics can be the used both in isolated hypertension and in concomitant coronary heart disease.

2014 ◽  
Vol 11 (4) ◽  
pp. 9-16
Author(s):  
O D Ostroumova

The article presents the results of an analysis of the Russian part of the international registry of variability in blood pressure. It is shown that in a real clinical practice antihypertensive therapy reduces inter-visit variability of systolic and diastolic blood pressure. It has been found that the fixed combination of perindopril arginine / amlodipine has antihypertensive effect and its impact on the variability of systolic blood pressure exceeds that for other modes of antihypertensive therapy. Revealed patterns are characteristic also for subgroups of patients with a combination of hypertension and coronary heart disease, hypertension and diabetes.


2018 ◽  
Vol 15 (3) ◽  
pp. 21-26
Author(s):  
V V Skibitsky ◽  
E V Gorodetskaya ◽  
E A Kudryashov ◽  
A V Fendrikova ◽  
A V Skibitsky

Aim - to assess the effect of different dosing regimens for combined antihypertensive therapy with the use of ACE inhibitor zofenopril or angiotensin II receptor blocker valsartan on the blood pressure (BP) profile in men and women with arterial hypertension (AH) and stable coronary heart disease (CHD). Materials and methods. 198 patients (98 men and 100 women) with AH and stable CHD (stable angina of II functional class) were examined. In men and women, the effectiveness of 3 variants of antihypertensive therapy was evaluated: a combination of metoprolol succinate/hydrochlorothiazide + zofenopril or valsartan 160 mg once or valsartan 80 mg 2 times/day. Initially and 24 weeks later, 24-hour BP monitoring was performed. Results. Among men, BP


2011 ◽  
Vol 14 (2) ◽  
pp. 249 ◽  
Author(s):  
Paulo Roque Obreli Neto ◽  
Srecko Marusic ◽  
Divaldo Pereira De Lyra Júnior ◽  
Diogo Pilger ◽  
Joice Mara Cruciol-Souza ◽  
...  

Purpose. To examine the effect of a pharmaceutical care program on the coronary heart disease risk in elderly diabetic and hypertensive patients. Methods. A total of 200 elderly (> 60 years) diabetic and/or hypertensive patients were recruited into a randomized, controlled, prospective clinical trial with a 36-month follow-up, developed in a public primary health care unit in a municipality in the Brazilian State of Sao Paulo. A range of clinical measurements were evaluated at the baseline and up to 36 months afterwards. The intervention group patients received pharmaceutical care from a clinical pharmacist, whereas the control group patients received their usual care from the medical and nursing staff. The Framingham scoring method was used to estimate changes in the 10-year coronary heart disease risk scores of all the patients. Results. A total of 194 patients completed the study. Significant reductions (p < 0.05) in the mean values (baseline vs. 36 months) for the systolic blood pressure [156.7mmHg vs 133.7mmHg; p


2017 ◽  
Vol 26 (3) ◽  
pp. 174-180 ◽  
Author(s):  
Marcin Wirtwein ◽  
Olle Melander ◽  
Marketa Sjőgren ◽  
Michal Hoffmann ◽  
Krzysztof Narkiewicz ◽  
...  

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