THE ROLE OF EARLY REHABILITATION AFTER CAROTID ENDARTERECTOMY IN ACUTE PERIOD OF ISCHEMIC STROKE

The aim of our study was to evaluate the role of early rehabilitation of patients with ischemic stroke after carotid endarterectomy. Material and methods. We examined a group of 28 patients with atherosclerotic carotid stenosis who had CEA in an acute period of stroke and who started rehabilitation in the early period of stroke. Patients of the 1st group were admitted to rehabilitation in the early stages (within 21 days after the stroke), patients of the 2nd group - in the delayed period (more than 60 days after the stroke).The results of treatment were assessed on the NIHSS scale, Rankin scale, Rivermead mobility scale, spasticity was assessed on the Ashworth scale. Results. An analysis of the long-term results of surgical treatment convincingly showed its positive effect on the neurological and neuropsychological status of patients with the most favorable outcomes in performing early rehabilitation.

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Long-term results of carotid endarterectomy performed in the acute period of ischemic stroke

Kardiologiya i serdechno-sosudistaya khirurgiya ◽

10.17116/kardio201912041286 ◽

2019 ◽

Vol 12 (4) ◽

pp. 286 ◽

Cited By ~ 1

Author(s):

N. R. Zakirzhanov ◽

R. N. Komarov ◽

V. V. Evseeva ◽

E. A. Gaziev ◽

I. I. Khalilov

Keyword(s):

Ischemic Stroke ◽

Carotid Endarterectomy ◽

Long Term Results ◽

Acute Period

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Role of dyslipidemia in ischemic stroke patients treated in the telestroke network

Advances in Medical Sciences ◽

10.1016/j.advms.2021.04.003 ◽

2021 ◽

Vol 66 (2) ◽

pp. 254-261

Author(s):

Leanne Brechtel ◽

Nicolas Poupore ◽

Margaret Monroe ◽

Krista Knisley ◽

Carolyn Sanders ◽

...

Keyword(s):

Ischemic Stroke ◽

Stroke Patients

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Role of Monitoring in Management of Acute Ischemic Stroke Patients

Stroke ◽

10.1161/01.str.0000094423.34841.bb ◽

2003 ◽

Vol 34 (11) ◽

pp. 2599-2603 ◽

Cited By ~ 76

Author(s):

Anna Cavallini ◽

Giuseppe Micieli ◽

Simona Marcheselli ◽

Silvana Quaglini

Keyword(s):

Ischemic Stroke ◽

Acute Ischemic Stroke ◽

Stroke Patients

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Influence of insulin resistance on the course of ischemic stroke in the acute period

Practical medicine ◽

10.32000/2072-1757-2020-5-93-98 ◽

2020 ◽

Vol 18 (5) ◽

pp. 93-98

Author(s):

L. B. NOVIKOVA ◽

◽

G. I. IZHBULDINA ◽

Keyword(s):

Insulin Resistance ◽

Ischemic Stroke ◽

Clinical Outcome ◽

Carbohydrate Metabolism ◽

Neurological Deficit ◽

Glucose Metabolism Disorders ◽

C Peptide ◽

Acute Period

Among the reasons that increase the risk of stroke, its severity and outcome, a special place is given to disorders of carbohydrate metabolism. However, to date, there is no consensus on the role of hyperglycemia in stroke, whether it is physiological or pathological. The purpose to study the effect of insulin resistance on the course and clinical outcome of ischemic stroke (IS) in the acute period. Material and methods. A total of 862 patients with IS (370 men, 492 women), mean age was 66,1 ± 10,8 years. The degree of neurological deficit (NIHSS scale) and clinical outcome were assessed. When admitted to hospital, the level of glycemia, insulin, and C-peptide in the fasting blood were found. Results. In 186 (21,6%) patients type 2 diabetes mellitus (DM) was diagnosed. In 27,8% of patients without DM and 76,3% of patients with DM hyperglycemia was detected. In patients without DM with hyperglycemia, compared with patients with normoglycemia, a higher representation of severe neurological deficit (by 14,7%), a lower frequency of noticeable positive dynamics (by 14,8%), and a higher mortality rate (by 11,5%) were found. In patients with DM, hyperglycemia was associated with a lower incidence of noticeable positive dynamics (by 27,7%). The development of IS is accompanied by an increase in the blood level of C-peptide more than twice. High values of the C-peptide/insulin ratio are associated with a higher frequency of severe neurological deficit in patients with DM (by 32,4%) and without DM (by 23,8%), and a decrease in the incidence of noticeable positive dynamics (by 23,5% and 20,9%, respectively). Conclusion. Development of IS is characterized by high representation of disorders of carbohydrate metabolism. The severity of glucose metabolism disorders is interrelated with the severity and clinical outcome of the disease.

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Evaluating the Role of Oxidative Stress in Acute Ischemic Stroke

Journal of Neurosciences in Rural Practice ◽

10.1055/s-0039-3402675 ◽

2020 ◽

Vol 11 (01) ◽

pp. 156-159

Author(s):

Bindu Menon ◽

Krishnan Ramalingam ◽

Rajeev Kumar

Keyword(s):

Oxidative Stress ◽

Ischemic Stroke ◽

Acute Stroke ◽

Acute Ischemic Stroke ◽

Lipid Membranes ◽

Demographic Data ◽

Stroke Severity ◽

Stroke Patients ◽

Antioxidant Power

Abstract Background The role of oxidative stress in neuronal injury due to ischemic stroke has been an interesting topic in stroke research. Malondialdehyde (MDA) has emerged as a sensitive oxidative stress biomarker owing to its ability to react with the lipid membranes. Total antioxidant power (TAP) is another biomarker to estimate the total oxidative stress in stroke patients. We aimed to determine the oxidative stress in acute stroke patients by measuring MDA and TAP. Materials and Methods MDA and TAP were determined in 100 patients with ischemic stroke and compared with that in 100 age- and sex-matched healthy adults. Demographic data, stroke severity measured by the National Institutes of Health Stroke Scale (NIHSS), and disability measured by the Barthel index (BI) were recorded. The association of MDA and TAP with other variables was analyzed by paired t-test. Results Of the whole sample, 74% represented males. The mean NIHSS score was 13.11 and BI was 38.87. MDA was significantly higher in stroke patients (7.11 ± 1.67) than in controls (1.64 ± 0.82; p = 0.00). TAP was significantly lower in stroke patients (5.72 ± 1.41) than in controls (8.53 ± 2.4; p = 0.00). The lipid profile and blood sugar levels were also significantly higher in stroke patients. There was no association of MDA and TAP with other variables. Conclusion We found that oxidative stress was associated with acute ischemic stroke. However, we could not establish an association between oxidative stress and the severity of acute stroke.

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Role of the Neurosurgeon in Acute Ischemic Stroke Treatment From Triage to Intensive Care Unit

Neurosurgery ◽

10.1093/neuros/nyz013 ◽

2019 ◽

Vol 85 (suppl_1) ◽

pp. S47-S51

Author(s):

Kimberly P Kicielinski ◽

Christopher S Ogilvy

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Ischemic Stroke ◽

Acute Ischemic Stroke ◽

Mechanical Thrombectomy ◽

Stroke Care ◽

Stroke Patients ◽

Acute Setting ◽

Stroke Treatment

Abstract As ischemic stroke care advances with more patients eligible for mechanical thrombectomy, so too does the role of the neurosurgeon in these patients. Neurosurgeons are an important member of the team from triage through the intensive care unit. This paper explores current research and insights on the contributions of neurosurgeons in care of acute ischemic stroke patients in the acute setting.

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In-hospital outcomes of carotid endarterectomy in acute period of ischemic stroke: single-center register data

Kardiologiya i serdechno-sosudistaya khirurgiya ◽

10.17116/kardio20181105160 ◽

2018 ◽

Vol 11 (5) ◽

pp. 60 ◽

Cited By ~ 2

Author(s):

R. S. Tarasov ◽

A. N. Kazantsev ◽

I. V. Moldavskaya ◽

N. N. Burkov ◽

A. V. Mironov ◽

...

Keyword(s):

Ischemic Stroke ◽

Carotid Endarterectomy ◽

Single Center ◽

Hospital Outcomes ◽

Acute Period

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Association of serum growth differentiation factor-15 with risk of death and vascular events in acute ischemic stroke patients: The role of diabetes

Atherosclerosis ◽

10.1016/j.atherosclerosis.2021.06.162 ◽

2021 ◽

Vol 331 ◽

pp. e57

Author(s):

P. Yang ◽

Z. Zhu ◽

J. Yin ◽

Y. Zhang

Keyword(s):

Ischemic Stroke ◽

Acute Ischemic Stroke ◽

Stroke Patients ◽

Vascular Events ◽

Growth Differentiation Factor 15 ◽

Risk Of Death ◽

Differentiation Factor

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The Frequency of Phospholipid Antibodies in an Unselected Stroke Population

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100033515 ◽

1998 ◽

Vol 25 (1) ◽

pp. 64-69 ◽

Cited By ~ 44

Author(s):

L.M. Metz ◽

S. Edworthy ◽

R. Mydlarski ◽

M.J. Fritzler

Keyword(s):

Ischemic Stroke ◽

Systemic Sclerosis ◽

Antiphospholipid Antibodies ◽

Anticardiolipin Antibodies ◽

Activated Partial Thromboplastin Time ◽

Systemic Lupus Erythematosis ◽

Stroke Patients ◽

Systemic Lupus ◽

Stroke Population

ABSTRACT:Background:Antibodies to cardiolipin and other phospholipids have been associated with recurrent thrombotic events, including stroke.Methods:Over a 16 month period we assessed an unselected cohort of 151 ischemic stroke patients for the presence of antiphospholipid antibodies. Patients with known systemic lupus erythematosis, systemic sclerosis, or Sjogrens Syndrome were excluded. Sera from patients admitted to hospital with a diagnosis of ischemic stroke (n = 151) and from controls (n = 111) assessed during the same period were tested for antiphospholipid antibodies (APLA) using 3 assays; anticardiolipin antibodies (ACA) by ELISA, prolonged activated partial thromboplastin time (APTT), and VDRL.Results:The average age of ischemic stroke cases was 68 years (range 29 to 91) and of controls 63 years (range 29 to 86). The prevalence of APLA detected by at least one of the three methods was 12% for IS cases and 10% for controls. After correcting for known risk factors such as age, gender, diabetes mellitus, heart disease, hypertension, and smoking, the odds ratio for risk of stroke fell to 0.8 (C.I. 0.4 to 1.2).Conclusions:Our findings suggest that APLA may not be an independent risk factor for ischemic stroke in unselected persons who do not have known systemic lupus erythematosis or systemic sclerosis but further evaluation of the role of lupus anticoagulant is indicated.

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