scholarly journals The Role of Substance P in Chronic Low Back Pain (CLBP)

2020 ◽  
Vol 4 (2) ◽  
pp. 9
Author(s):  
Yusnita Rachmawati

<p>Low Back Pain is one of the disease that causing global disability in the worldwide. In the past 10 years, prevalence of LBP has not decreased, it makes global burden increase substantially. Chronic low back pain(CLBP) is pain that is almost experienced daily by patients in the lower back region in a period of more than 3 months. Chronic low back pain is a mixture of pain that arises through nociceptive and neuropathic mechanisms. Over the past decade, numerous  guidelines have been used  in the management of CLBP. Problems that are still a controversy include the management of pain. The mechanism of many treatment measures is still in the low to moderate effectiveness stage, so that the pain management target is not optimal. Substance P is a neuropeptide that release  both in acute and chronic pain. Therefore study about mechanisms that affect SP release may show important information regarding pathological alterations in pain perception.</p>

Pain ◽  
1993 ◽  
Vol 52 (2) ◽  
pp. 157-168 ◽  
Author(s):  
Gordon Waddell ◽  
Mary Newton ◽  
Iain Henderson ◽  
Douglas Somerville ◽  
Chris J. Main

Physiotherapy ◽  
2008 ◽  
Vol 94 (2) ◽  
pp. 115-124 ◽  
Author(s):  
Steve R. Woby ◽  
Neil K. Roach ◽  
Martin Urmston ◽  
Paul J. Watson

2021 ◽  
Vol 9 (11) ◽  
pp. 2909-2913
Author(s):  
Kavita Kavita ◽  
Suresh N Hakkandi ◽  
Manjunath Akki

Lower Back Pain can have causes that aren’t due to underlying diseases and this pain refers to the pain that usual- ly begins in the lower back region, radiating to the sacroiliac regions and buttocks.[1] People with chronic pain often find it difficult to cope with work, family and social activities which is the significant cause of disability worldwide. Eighty percent of the population is affected by this symptom sometimes in life.[2] Increased preva- lence of low back pain and temporary and reduced success rates in invasive contemporary treatment measures has drawn considerable attention towards alternative, effective, non-invasive treatment modalities. Katishoola, a Vata vyadhi diagnosed with cardinal symptoms as Pain in Kati Pradesha. In Ayurveda, a holistic approach has been adopted that includes the use of oral Ayurvedic formulations, Panchakarma procedures like Snehana karma (unc- tion therapy), Swedana karma (sudation therapy) etc. [3] Here In this article a case of low Back Pain treated with Kati Pichu with Masha taila with good outcomes are reported. Keywords: Katishoola, Low Back Pain, Masha Taila, Kati Pichu


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