Common Drugs: Medication Guide

Abstract: Pulmonary tuberculosis is a chronic infection and still a major worldwide health problem. Data from World Health Organization in 2013 showed that Indonesia was the fifth country with the highest prevalence of TB in the world. Treatment of TB in Indonesia is using the antituberculosis medication guide. One of the side effects of treatment is hepatotoxicity. Liver function tests commonly used are the transaminase enzymes (SGOT and SGPT). Levels of SGOT and SGPT will increase in case of damage or inflammation of the liver tissue. The results showed that after administration of the antituberculosis medication 26% of patients had high levels of transaminase enzymes meanwhile 74% of patients had normal levels of transaminase enzymes.Keywords: Pulmonal Tuberculosis, OAT, hepatotoxicity, transaminase enzymes, SGOT, SGPT Abstrak: Tuberkulosis paru adalah infeksi kronik yang sampai saat ini masih menjadi masalah kesehatan dunia yang utama. Data WHO tahun 2013 menunjukkan bahwa Indonesia menempati negara kelima dengan prevalensi TB tertinggi di dunia. Pengobatan TB di Indonesia menggunakan panduan obat antituberkuolosis (OAT) dan salah satu efek samping pengobatan ialah hepatotoksisitas. Tes fungsi hati yang umum digunakan ialah pemeriksaan enzim transaminase yakni kadar SGOT dan SGPT yang akan menunjukkan peningkatan jika terjadi kerusakan atau radang pada jaringan hati. Hasil penelitian memperlihatkan terdapat 26% pasien TB dengan kadar enzim transaminase yang tinggi setelah pemberian OAT, dan 74% pasien TB yang memiliki kadar enzim transaminase yang normal setelah pemberian OAT.Kata kunci: tuberkulosis paru, OAT, hepatotoksisitas, enzim transaminase, SGOT, SGPT

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Management of Complex Treatment-resistant Psychotic Disorders

10.1017/9781108963923 ◽

2021 ◽

Keyword(s):

Mental Health Professionals ◽

Psychotic Disorders ◽

Response Monitoring ◽

Complex Treatment ◽

Treatment Resistant ◽

Full Color ◽

Medication Guide ◽

Essential Resource ◽

Typical Treatment ◽

Derived Data

This full-color, practical handbook provides a concise, evidence-based psychopharmacological approach to the management of complex treatment-resistant psychotic disorders. Part I focuses uniquely on topics and strategies relevant to treating this challenging patient population. These approaches go beyond standard guidelines while adhering to research and clinically derived data. Part II provides a concise array of information regarding those classes of medications most commonly used when treating complex treatment-resistant psychotic disorders. Each medication guide contains sections including mechanisms of action, typical treatment response, monitoring, dosing and kinetics, medications to avoid in combination/warnings, and take-home pearls. Part III offers tips in brief appendix chapters for managing common issues ranging from loading lithium and valproic acid to the treatment of acute psychomotor agitation. An essential resource for psychiatrists, forensic clinicians, psychiatric trainees, and all mental health professionals involved with, or interested in, the treatment of challenging psychotic disorders.

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