The accuracy and completeness of drug information in Google snippet blocks

Introduction: Consumers commonly use the Internet for immediate drug information. In 2014, Google introduced the snippet block to programmatically search available websites to answer a question entered into the search engine without the need for the user to enter any websites. This study compared the accuracy and completeness of drug information found in Google snippet blocks to US Food and Drug Administration (FDA) medication guides.Methods: Ten outpatient drugs were selected from the 2018 Clinical Drugstats Database Medical Expenditure Panel Survey. Six questions in the medication guide for each drug were entered into the Google search engine to find the snippet block. The accuracy and completeness of drug information in the Google snippet block were quantified by two different pharmacists using a scoring system of 1 (less than 25% accurate/complete information) to 5 (100% accurate/complete information). Descriptive statistics were used to summarize the scores.Results: For five out of the six questions, the information in the Google snippets had less than 50% accuracy and completeness compared to the medication guides. The average accuracy and completeness scores of the Google snippets were highest for “What are the ingredients of [the drug]?” with scores of 3.38 (51–75%) and 3.00 (51–75%), respectively. The question on “How to take [drug]?” had the lowest score with averages of 1.00 (<25%) for both accuracy and completeness.Conclusion: Google snippets provide inaccurate and incomplete drug information when compared to FDA-approved drug medication guides. This aspect may cause patient harm; therefore, it is imperative for health care and health information professionals to provide reliable drug resources to patients and consumers if written information may be needed.

Management of Complex Treatment-resistant Psychotic Disorders

This full-color, practical handbook provides a concise, evidence-based psychopharmacological approach to the management of complex treatment-resistant psychotic disorders. Part I focuses uniquely on topics and strategies relevant to treating this challenging patient population. These approaches go beyond standard guidelines while adhering to research and clinically derived data. Part II provides a concise array of information regarding those classes of medications most commonly used when treating complex treatment-resistant psychotic disorders. Each medication guide contains sections including mechanisms of action, typical treatment response, monitoring, dosing and kinetics, medications to avoid in combination/warnings, and take-home pearls. Part III offers tips in brief appendix chapters for managing common issues ranging from loading lithium and valproic acid to the treatment of acute psychomotor agitation. An essential resource for psychiatrists, forensic clinicians, psychiatric trainees, and all mental health professionals involved with, or interested in, the treatment of challenging psychotic disorders.

Gambaran enzim transaminase pada pasien tuberkulosis paru yang diterapi dengan obat-obat anti tuberkulosis di RSUP Prof. Dr. R. D. Kandou Manado

Pulmonary tuberculosis is a chronic infection and still a major worldwide health problem. Data from World Health Organization in 2013 showed that Indonesia was the fifth country with the highest prevalence of TB in the world. Treatment of TB in Indonesia is using the antituberculosis medication guide. One of the side effects of treatment is hepatotoxicity. Liver function tests commonly used are the transaminase enzymes (SGOT and SGPT). Levels of SGOT and SGPT will increase in case of damage or inflammation of the liver tissue. The results showed that after administration of the antituberculosis medication 26% of patients had high levels of transaminase enzymes meanwhile 74% of patients had normal levels of transaminase enzymes.Keywords: Pulmonal Tuberculosis, OAT, hepatotoxicity, transaminase enzymes, SGOT, SGPT Abstrak: Tuberkulosis paru adalah infeksi kronik yang sampai saat ini masih menjadi masalah kesehatan dunia yang utama. Data WHO tahun 2013 menunjukkan bahwa Indonesia menempati negara kelima dengan prevalensi TB tertinggi di dunia. Pengobatan TB di Indonesia menggunakan panduan obat antituberkuolosis (OAT) dan salah satu efek samping pengobatan ialah hepatotoksisitas. Tes fungsi hati yang umum digunakan ialah pemeriksaan enzim transaminase yakni kadar SGOT dan SGPT yang akan menunjukkan peningkatan jika terjadi kerusakan atau radang pada jaringan hati. Hasil penelitian memperlihatkan terdapat 26% pasien TB dengan kadar enzim transaminase yang tinggi setelah pemberian OAT, dan 74% pasien TB yang memiliki kadar enzim transaminase yang normal setelah pemberian OAT.Kata kunci: tuberkulosis paru, OAT, hepatotoksisitas, enzim transaminase, SGOT, SGPT