Black Lives, Green Books, and Blue Checks

The Negro Motorist Green Book was a publication that offered resources for the Black traveler from 1936 to 1966. More than a directory of Black-friendly businesses, it also offered articles that provided insights for how best to travel safely, engagement with readers through contests and invitations for readers to share travel stories, and even civil rights advocacy. Today, a contemporary counterpart to the Green Book is Black Twitter, where people share information and advocate for their community. By conducting qualitative open coding on a subset of Green Book editions as well as tweets from Black Twitter, we explore similarities and overlapping characteristics such as safety, information sharing, and social justice. Where they diverge exposes how spaces like Black Twitter have evolved to accommodate the needs of people in the Black diaspora beyond the scope of physical travel and into digital spaces. Our research points to ways that the Black community has shifted from the physical to the digital space, expanding how it supports itself, and the potential for research to strengthen throughlines between the past and the present in order to better see the possibilities of the future.

Women’s views on accepting COVID-19 vaccination during and after pregnancy, and for their babies: a multi-methods study in the UK

Background COVID-19 vaccines are advised for pregnant women in the United Kingdom (UK) however COVID-19 vaccine uptake among pregnant women is inadequate. Methods An online survey and semi-structured interviews were used to investigate pregnant women’s views on COVID-19 vaccine acceptability for themselves when pregnant, not pregnant and for their babies. One thousand one hundred eighty-one women, aged over 16 years, who had been pregnant since 23rd March 2020, were surveyed between 3rd August–11th October 2020. Ten women were interviewed. Results The majority of women surveyed (81.2%) reported that they would ‘definitely’ or were ‘leaning towards’ accepting a COVID-19 vaccine when not pregnant. COVID-19 vaccine acceptance was significantly lower during pregnancy (62.1%, p < 0.005) and for their babies (69.9%, p < 0.005). Ethnic minority women were twice as likely to reject a COVID-19 vaccine for themselves when not pregnant, pregnant and for their babies compared to women from White ethnic groups (p < 0.005). Women from lower-income households, aged under 25-years, and from some geographic regions were more likely to reject a COVID-19 vaccine when not pregnant, pregnant and for their babies. Multivariate analysis revealed that income and ethnicity were the main drivers of the observed age and regional differences. Women unvaccinated against pertussis in pregnancy were over four times more likely to reject COVID-19 vaccines when not pregnant, pregnant and for their babies. Thematic analysis of the survey freetext responses and interviews found safety concerns about COVID-19 vaccines were common though wider mistrust in vaccines was also expressed. Trust in vaccines and the health system were also reasons women gave for accepting COVID-19 vaccines. Conclusion Safety information on COVID-19 vaccines must be clearly communicated to pregnant women to provide reassurance and facilitate informed pregnancy vaccine decisions. Targeted interventions to promote COVID-19 vaccine uptake among ethnic minority and lower-income women may be needed.

Design and Development of Maritime Data Security Management Platform

Since the e-Navigation strategy was put forward, various countries and regions in the world have researched e-Navigation test platforms. However, the sources of navigation data are multi-source, and there are still difficulties in the unified acquisition, processing, analysis and application of multi-source data. Users often find it difficult to obtain the required comprehensive navigation information. The purpose of this paper is to use e-Navigation architecture to design and develop maritime data security management platform, strengthen navigation safety guarantee, strengthen Marine environment monitoring, share navigation and safety information, improve the ability of shipping transportation organizations in ports, and protect the marine environment. Therefore, this paper proposes a four-layer system architecture based on Java 2 Platform Enterprise Edition (J2EE) technology, and designs a unified maritime data storage, analysis and management platform, which realizes the intelligent, visualized and modular management of maritime data at shipside and the shore. This platform can provide comprehensive data resource services for ship navigation and support the analysis and mining of maritime big data. This paper expounds on the design, development scheme and demonstration operation scheme of the maritime data security management platform from the system structure and data exchange mode.

Finerenone: A Novel Mineralocorticoid Receptor Antagonist for Cardiorenal Protection in CKD and T2DM

Objective: To describe the pharmacology, clinical and safety evidence, and relevance to clinical practice of finerenone. Data Sources: A literature search was conducted utilizing PubMed, MEDLINE, and clinicaltrials.gov with search terms of “finerenone” and “BAY94-8862.” Study Selection and Data Extraction All available studies with human participants in English were considered. Studies were included if they investigated drug pharmacology, efficacy, and safety information. Data Synthesis In addition to standard of care with a renin-angiotensin system inhibitor (RASi), finerenone lowered the risk of kidney disease progression (17.8% vs 21.1%) in patients with type 2 diabetes mellitus and chronic kidney disease compared to placebo. Similarly, finerenone reduced cardiovascular risk in patients with type 2 diabetes mellitus and chronic kidney disease compared to placebo (12.4% vs 14.2%). Relevance to Patient Care and Clinical Practice It is anticipated that finerenone will be added to therapy after a RASi and a sodium-glucose cotransporter-2 inhibitor, as tolerated, based on adverse events and potassium levels. Conclusions Finerenone offers a unique approach to further delay the progression of chronic kidney disease in patients with type 2 diabetes mellitus. It also provides another option for patients who cannot tolerate RASi or sodium-glucose cotransporter-2 inhibitors.

Data-Driven Construction Safety Information Sharing System Based on Linked Data, Ontologies, and Knowledge Graph Technologies

Accident, injury, and fatality rates remain disproportionately high in the construction industry. Information from past mishaps provides an opportunity to acquire insights, gather lessons learned, and systematically improve safety outcomes. Advances in data science and industry 4.0 present new unprecedented opportunities for the industry to leverage, share, and reuse safety information more efficiently. However, potential benefits of information sharing are missed due to accident data being inconsistently formatted, non-machine-readable, and inaccessible. Hence, learning opportunities and insights cannot be captured and disseminated to proactively prevent accidents. To address these issues, a novel information sharing system is proposed utilizing linked data, ontologies, and knowledge graph technologies. An ontological approach is developed to semantically model safety information and formalize knowledge pertaining to accident cases. A multi-algorithmic approach is developed for automatically processing and converting accident case data to a resource description framework (RDF), and the SPARQL protocol is deployed to enable query functionalities. Trials and test scenarios utilizing a dataset of 200 real accident cases confirm the effectiveness and efficiency of the system in improving information access, retrieval, and reusability. The proposed development facilitates a new “open” information sharing paradigm with major implications for industry 4.0 and data-driven applications in construction safety management.

Identifying risk factors and implications for beach drowning prevention amongst an Australian multicultural community

Multicultural communities in Australia are recognised as a priority area for drowning prevention, but no evidence-based study has addressed their knowledge of beach safety. This study used an online survey tool to identify and examine risk factors relating to swimming ability, beach visitation characteristics and behaviour, and beach safety knowledge of the Australian Southern Asian community to assist in the development of future beach safety interventions. Data was obtained through 249 online and in-person surveys of people aged > 18 years. Most respondents reported poor swimming ability (80%), often swam in in the absence of lifeguards (77%), did not understand the rip current hazard (58%), but reported that they entered the water (76%) when visiting beaches. Close to one-quarter (28%) had not heard, or didn’t know the purpose, of the red and yellow beach flags, which identify lifeguard supervised areas on Australian beaches. Length of time living in Australia is an important beach safety consideration for this community, with minimal differences in terms of gender and age. Those who have lived < 10 years in Australia visit beaches more frequently and are less likely to have participated in swimming lessons, be able to swim, heard of the flags or swim between them, understand rip currents, or have participated in a beach safety program. Very few (3%) respondents received beach safety information from within their own community. The importance of beach safety education and swimming lessons within the Southern Asian community should be prioritised for new and recent migrants to Australia.

Assessing Potential Safety Zone Suitability Using a New Online Mapping Tool

Safety zones (SZs) are critical tools that can be used by wildland firefighters to avoid injury or fatality when engaging a fire. Effective SZs provide safe separation distance (SSD) from surrounding flames, ensuring that a fire’s heat cannot cause burn injury to firefighters within the SZ. Evaluating SSD on the ground can be challenging, and underestimating SSD can be fatal. We introduce a new online tool for mapping SSD based on vegetation height, terrain slope, wind speed, and burning condition: the Safe Separation Distance Evaluator (SSDE). It allows users to draw a potential SZ polygon and estimate SSD and the extent to which that SZ polygon may be suitable, given the local landscape, weather, and fire conditions. We begin by describing the algorithm that underlies SSDE. Given the importance of vegetation height for assessing SSD, we then describe an analysis that compares LANDFIRE Existing Vegetation Height and a recent Global Ecosystem Dynamics Investigation (GEDI) and Landsat 8 Operational Land Imager (OLI) satellite image-driven forest height dataset to vegetation heights derived from airborne lidar data in three areas of the Western US. This analysis revealed that both LANDFIRE and GEDI/Landsat tended to underestimate vegetation heights, which translates into an underestimation of SSD. To rectify this underestimation, we performed a bias-correction procedure that adjusted vegetation heights to more closely resemble those of the lidar data. SSDE is a tool that can provide valuable safety information to wildland fire personnel who are charged with the critical responsibility of protecting the public and landscapes from increasingly intense and frequent fires in a changing climate. However, as it is based on data that possess inherent uncertainty, it is essential that all SZ polygons evaluated using SSDE are validated on the ground prior to use.

Host microbiomes in tumor precision medicine: how far are we?

The human gut microbiome has received a crescendo of attention in recent years, due to the countless influences on human pathophysiology, including cancer. Research on cancer and anticancer therapy is constantly looking for new hints to improve the response to therapy while reducing the risk of relapse. In this scenario, the gut microbiome and the plethora of microbial-derived metabolites are considered a new opening in the development of innovative anticancer treatments for a better prognosis. This narrative review summarizes the current knowledge on the role of the gut microbiome in the onset and progression of cancer, as well as in response to chemo-immunotherapy. Recent findings regarding the tumor microbiome and its implications for clinical practice are also commented on. Current microbiome-based intervention strategies (i.e., prebiotics, probiotics, live biotherapeutics and fecal microbiota transplantation) are then discussed, along with key shortcomings, including a lack of long-term safety information in patients who are already severely compromised by standard treatments. The implementation of bioinformatic tools applied to microbiomics and other omics data, such as machine learning, has an enormous potential to push research in the field, enabling the prediction of health risk and therapeutic outcomes, for a truly personalized precision medicine.

Does tai chi improve psychological well-being and quality of life in patients with cardiovascular disease and/or cardiovascular risk factors? A systematic review

Background Psychological risk factors have been recognised as potential, modifiable risk factors in the development and progression of cardiovascular disease (CVD). Tai Chi, a mind-body exercise, has the potential to improve psychological well-being and quality of life. We aim to assess the effects and safety of Tai Chi on psychological well-being and quality of life in people with CVD and/or cardiovascular risk factors. Methods We searched for randomised controlled trials evaluating Tai Chi for psychological well-being and quality of life in people with CVD and cardiovascular risk factors, from major English and Chinese databases until 30 July 2021. Two authors independently conducted study selection and data extraction. Methodological quality was evaluated using the Cochrane Risk of Bias tool. Review Manager software was used for meta-analysis. Results We included 37 studies (38 reports) involving 3525 participants in this review. The methodological quality of the included studies was generally poor. Positive effects of Tai Chi on stress, self-efficacy, and mood were found in several individual studies. Meta-analyses demonstrated favourable effects of Tai Chi plus usual care in reducing anxiety (SMD − 2.13, 95% confidence interval (CI): − 2.55, − 1.70, 3 studies, I2 = 60%) and depression (SMD -0.86, 95% CI: − 1.35, − 0.37, 6 studies, I2 = 88%), and improving mental health (MD 7.86, 95% CI: 5.20, 10.52, 11 studies, I2 = 71%) and bodily pain (MD 6.76, 95% CI: 4.13, 9.39, 11 studies, I2 = 75%) domains of the 36-Item Short Form Survey (scale from 0 to 100), compared with usual care alone. Tai Chi did not increase adverse events (RR 0.50, 95% CI: 0.21, 1.20, 5 RCTs, I2 = 0%), compared with control group. However, less than 30% of included studies reported safety information. Conclusions Tai Chi seems to be beneficial in the management of anxiety, depression, and quality of life, and safe to practice in people with CVD and/or cardiovascular risk factors. Monitoring and reporting of safety information are highly recommended for future research. More well-designed studies are warranted to determine the effects and safety of Tai Chi on psychological well-being and quality of life in this population. Systematic review registration International Prospective Register for Systematic Reviews (PROSPERO), CRD42016042905. Registered on 26 August 2016.

A Systematic Review on the Usability of Web-Based Applications in Advocating Consumers on Food Safety

Food safety is an important indicator of public health, as foodborne illnesses continue to cause productivity and economic loss. In recent years, web-based applications have been extensively used by the online users’ population. Almost one third (28.3%) of online users found web-based application to be a notable source of food safety information. The objective of the current review is to determine the effectiveness of a web-based application systems as a health promotion tool for consumers to increase their knowledge and awareness of food safety. A systematic literature review was conducted by analyzing 11 selected web-based food safety education-related articles. The studies were categorized into several themes: (1) web-based applications used in accessing food safety information; (2) food safety evaluation and perception among consumers; (3) beliefs and level of knowledge, attitude and practices (KAP) of consumers; and (4) impact and contribution of social media use. A diverse number of online applications have been utilized to promote food safety education among consumers, yet these web-based applications need to be improved with regards to social connection and integration among consumers. KAP surveys were conducted on the majority of the respondents with a particular focus on their knowledge level. Findings show that web-based applications may act as an alternative to the traditional media in enhancing food safety education among consumers, especially youths who are tech-savvy.