FITNESS COST OF RESISTANCE TO CADMIUM IN THE LEAST KILLIFISH (HETERANDRIA FORMOSA)

10.1897/03-96 ◽  
2004 ◽  
Vol 23 (6) ◽  
pp. 1499 ◽  
Author(s):  
Lingtian Xie ◽  
Paul L. Klerks
Keyword(s):  
Fitness Cost ◽  
Heterandria Formosa ◽  
Cost Of Resistance ◽  
Least Killifish

scholarly journals The Fitness Cost of Mutations Associated with Human Immunodeficiency Virus Type 1 Drug Resistance Is Modulated by Mutational Interactions

2006 ◽  
Vol 81 (6) ◽  
pp. 3037-3041 ◽  
Author(s):  
Mian-er Cong ◽  
Walid Heneine ◽  
J. Gerardo García-Lerma
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Fitness Cost ◽  
Resistance Mutations ◽  
Drug Pressure ◽  
Critical Determinant ◽  
Immunodeficiency Virus ◽  
Cost Of Resistance

ABSTRACT It is generally accepted that the fitness cost of resistance mutations plays a role in the persistence of transmitted drug-resistant human immunodeficiency virus type 1 and that mutations that confer a high fitness cost are less able to persist in the absence of drug pressure. Here, we show that the fitness cost of reverse transcriptase (RT) mutations can vary within a 72-fold range. We also demonstrate that the fitness cost of M184V and K70R can be decreased or enhanced by other resistance mutations such as D67N and K219Q. We conclude that the persistence of transmitted RT mutants might range widely on the basis of fitness and that the modulation of fitness cost by mutational interactions will be a critical determinant of persistence.

scholarly journals Reversing resistance: different routes and common themes across pathogens

2017 ◽  
Vol 284 (1863) ◽  
pp. 20171619 ◽  
Author(s):  
Richard C. Allen ◽  
Jan Engelstädter ◽  
Sebastian Bonhoeffer ◽  
Bruce A. McDonald ◽  
Alex R. Hall
Keyword(s):  
Fitness Cost ◽  
Biological Processes ◽  
Short Supply ◽  
Compensatory Evolution ◽  
Wide Range ◽  
Different Types ◽  
Cost Of Resistance

Resistance spreads rapidly in pathogen or pest populations exposed to biocides, such as fungicides and antibiotics, and in many cases new biocides are in short supply. How can resistance be reversed in order to prolong the effectiveness of available treatments? Some key parameters affecting reversion of resistance are well known, such as the fitness cost of resistance. However, the population biological processes that actually cause resistance to persist or decline remain poorly characterized, and consequently our ability to manage reversion of resistance is limited. Where do susceptible genotypes that replace resistant lineages come from? What is the epidemiological scale of reversion? What information do we need to predict the mechanisms or likelihood of reversion? Here, we define some of the population biological processes that can drive reversion, using examples from a wide range of taxa and biocides. These processes differ primarily in the origin of revertant genotypes, but also in their sensitivity to factors such as coselection and compensatory evolution that can alter the rate of reversion, and the likelihood that resistance will re-emerge upon re-exposure to biocides. We therefore argue that discriminating among different types of reversion allows for better prediction of where resistance is most likely to persist.

scholarly journals Three-dimensional analysis of the fast-start escape response of the least killifish,Heterandria formosa

2018 ◽  
Vol 221 (7) ◽  
pp. jeb168609 ◽  
Author(s):  
Mike Fleuren ◽  
Johan L. van Leeuwen ◽  
Elsa M. Quicazan-Rubio ◽  
Remco P. M. Pieters ◽  
Bart J. A. Pollux ◽  
...  
Keyword(s):  
Dimensional Analysis ◽  
Escape Response ◽  
Three Dimensional ◽  
Fast Start ◽  
Heterandria Formosa ◽  
Least Killifish

scholarly journals EFFECTS OF TEMPERATURE ON THE FITNESS COST OF RESISTANCE TO BACTERIOPHAGE T4 INESCHERICHIA COLI.

Evolution ◽  
2009 ◽  
Vol 63 (6) ◽  
pp. 1406-1416 ◽  
Author(s):  
Michael A. Quance ◽  
Michael Travisano
Keyword(s):  
Bacteriophage T4 ◽  
Fitness Cost ◽  
Inescherichia Coli ◽  
Cost Of Resistance ◽  
Effects Of Temperature

Variation in Fecundity and Its Relationship to Body Size in a Population of the Least Killifish, Heterandria formosa (Pisces: Poeciliidae)

Copeia ◽  
1984 ◽  
Vol 1984 (3) ◽  
pp. 720 ◽  
Author(s):  
Ron T. Cheong ◽  
Sabine Henrich ◽  
James A. Farr ◽  
Joseph Travis
Keyword(s):  
Body Size ◽  
Heterandria Formosa ◽  
Least Killifish

ADAPTIVE MATERNAL ADJUSTMENTS OF OFFSPRING SIZE IN RESPONSE TO CONSPECIFIC DENSITY IN TWO POPULATIONS OF THE LEAST KILLIFISH,HETERANDRIA FORMOSA

Evolution ◽  
2009 ◽  
Vol 63 (5) ◽  
pp. 1341-1347 ◽  
Author(s):  
Jeff Leips ◽  
Jean M. L. Richardson ◽  
F. Helen Rodd ◽  
Joseph Travis
Keyword(s):  
Offspring Size ◽  
Conspecific Density ◽  
Heterandria Formosa ◽  
Least Killifish ◽  
Two Populations

Mechanism, stability and fitness cost of resistance to pyriproxyfen in the house fly, Musca domestica L. (Diptera: Muscidae)

2015 ◽  
Vol 119 ◽  
pp. 67-73 ◽  
Author(s):  
Rizwan Mustafa Shah ◽  
Sarfraz Ali Shad ◽  
Naeem Abbas
Keyword(s):  
Musca Domestica ◽  
House Fly ◽  
Fitness Cost ◽  
Cost Of Resistance
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