scholarly journals Environmentally-friendly preparation of chitosan microspheres and encapsulation studies of cinnamaldehyde: Тowards convenient sustained release system for cinnamaldehyde

2021 ◽  
Vol 40 (2) ◽  
pp. 253
Author(s):  
Elif Karacan Yeldir ◽  
Ayhan Oral
Keyword(s):  
Sustained Release ◽  
Environmentally Friendly ◽  
Chitosan Microspheres ◽  
Release System

Preparation and characterization of carvedilol-loaded poly(d,l) lactide nanoparticles/microparticles as a sustained-release system

2017 ◽  
Vol 66 (14) ◽  
pp. 717-725 ◽  
Author(s):  
Mohyeddin Assali ◽  
Abdel Naser Zaid ◽  
Majd Bani-Odeh ◽  
Maryam Faroun ◽  
Riham Muzaffar ◽  
...  
Keyword(s):  
Sustained Release ◽  
Release System

scholarly journals Fabrication of a Cu/Zn co-incorporated calcium phosphate scaffold-derived GDF-5 sustained release system with enhanced angiogenesis and osteogenesis properties

RSC Advances ◽  
2018 ◽  
Vol 8 (52) ◽  
pp. 29526-29534 ◽  
Author(s):  
Dongqin Xiao ◽  
Fei Yang ◽  
Qiao Zhao ◽  
Shixiao Chen ◽  
Feng Shi ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Sustained Release ◽  
Release System

A Cu/Zn co-incorporated BCP scaffold-derived GDF-5 sustained release system was successfully prepared and exhibited improved angiogenic and osteogenic capacities.

Insulin-Loaded Silk Fibroin Microneedles as Sustained Release System

2019 ◽  
Vol 5 (4) ◽  
pp. 1887-1894 ◽  
Author(s):  
Shiyi Wang ◽  
Mingmei Zhu ◽  
Liang Zhao ◽  
Dajiang Kuang ◽  
Subhas C. Kundu ◽  
...  
Keyword(s):  
Sustained Release ◽  
Silk Fibroin ◽  
Release System

scholarly journals BIODEGRADABLE POLYMER: A NOVEL PHARMACEUTICAL CARRIER FOR SUSTAINED RELEASE OF METRONIDAZOLE

2017 ◽  
Vol 10 (10) ◽  
pp. 136
Author(s):  
Gayathri Hariharan ◽  
Priyanka Sinha
Keyword(s):  
Particle Size ◽  
Drug Release ◽  
Sustained Release ◽  
Biodegradable Polymer ◽  
Drug Loading ◽  
Cross Linking ◽  
Loading Capacity ◽  
Flow Properties ◽  
Chitosan Microspheres

Objective: To optimize and evaluate the formulation of metronidazole (MT)-loaded chitosan microspheres and to investigate the efficiency of biodegradable polymer in developing sustained release formulation of MT to prolong the action of drug.Methods: MT microspheres were prepared using emulsion cross-linking method. Polymer-drug compatibility study was done using Fourier transform infrared. Physical characteristics were evaluated by particle size,SEM, flow properties etc. In vitro studies for evaluating drug release for MT-loaded chitosan microspheres were done by dissolution study.Results: Particle size of the formulated microspheres was found to be within the range of 110-130 μm. Flow properties of F1-F7 such as angle of repose, bulk density, and tapped density were found to be within limits. Drug entrapment efficiency was found to be better for all the formulations within the range of 74.82-84.32% w/w. Drug loading capacity was found to be in the range of 56-83.2% w/v. In vitro drug release was found to be in the range of 81.32-96.23% w/v.Conclusion: In spite of all the above results, we conclude that F5 formulation was optimized depending on the data obtained from the drug loading capacity and percentage drug release studies. F5 formulation is formulated with drug-polymer ratio 1:2 with 1% of di octyl sodium sulfo succinate and 8 ml of glutaraldehyde as a cross-linking agent.

Polypseudorotaxanes of pegylated α-cyclodextrin/polyamidoamine dendrimer conjugate with cyclodextrins as a sustained release system for DNA

2012 ◽  
Vol 20 (4) ◽  
pp. 1425-1433 ◽  
Author(s):  
Keiichi Motoyama ◽  
Kayoko Hayashida ◽  
Taishi Higashi ◽  
Hidetoshi Arima
Keyword(s):  
Sustained Release ◽  
Polyamidoamine Dendrimer ◽  
Release System

Development of a Sustained-release System for Nitric Oxide Delivery using Alginate/Chitosan Nanoparticles

2013 ◽  
Vol 9 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Priscyla D. Marcato ◽  
Leonardo F. Adami ◽  
Raquel de Melo Barbosa ◽  
Patricia S. Melo ◽  
Iasmin R. Ferreira ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Sustained Release ◽  
Chitosan Nanoparticles ◽  
Release System ◽  
Nitric Oxide Delivery
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