scholarly journals Characteristics of Patients with End-Stage Renal Disease at Dialysis Unit Dr. Soetomo General Hospital Surabaya

2018 ◽  
Vol 1 (2) ◽  
pp. 97
Author(s):  
Leny Silviana Farida ◽  
Muhammad Thaha ◽  
Dwi Susanti

Introduction: The prevalence of end stage renal disease (ESRD) in Indonesia is increasing over the last decade. Most cases highest risk factor are Diabetes Mellitus (DM) and hypertension. Other factors such as lifestyle and environment; both play important role in the development of ESRD. Thus, this study aimed to assess the characteristic of patient with ESRD.Methods: This was a descriptive study acquired by interviewing 126 patients with ESRD who have been undergoing continuous hemodialysis in dialysis unit of Dr. Soetomo General Hospital Surabaya for at least 3 months using questionnaire about history of disease, smoking habit, sex, and ethnic group. All data was analyzed using frequency distribution and percentage.Results: Form 126 patients, consist of 61 male patients (48.4%) and 65 female (51.6%). 45 patients (35.7%) have the history of DM; 98 patients (77.0%) of hypertension; 35 patients (27.8%) of hypertension and DM; and 19 patients (15.1%) have none of them. Later age adult (36-45 years old) has the largest group proportion (34.13%). There are 36 patients (28%) who are smokers. 108 patients (85.7%) are Javanese.Conclusion: Most of the patients have hypertension as the risk factor and in later age group adult. Characteristics of patient with ESRD is caused by multifactorial factors. Therefore, patient with high risk factor should be aware and do preventive steps in progressiveness of the disease.

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Chang Seong Kim ◽  
Hong Sang Choi ◽  
Tae Ryom Oh ◽  
Eun hui Bae ◽  
Soo Wan Kim

Abstract Background and Aims Hypertension is the leading risk factor for end-stage renal disease (ESRD). However, the association between repeated measurements of high blood pressure and ESRD is not well-established. This study investigated whether the cumulative number of diagnoses of hypertension is a substantial risk factor for ESRD. Method The incidence of ESRD among 2,144,801 participants, identified from the Korean National Health Insurance Service database, who did not have a history of antihypertensive therapy and had documented blood pressure assessments for 4 consecutive years was determined retrospectively. Data were extracted from the database where events of hypertension were defined as systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg. Results Over a median follow-up of 7.2 years, ESRD was identified in 1758 of the 2,144,801 participants. In a multivariable Cox model adjusted for age, sex, smoking, alcohol consumption, exercise, and history of diabetes and chronic kidney disease, a positive dose-dependent relationship between the cumulative number of diagnoses of hypertension and ESRD was found (adjusted hazard ratio for ESRD, 2.70 in 4 cumulative number of diagnoses of hypertension compared to no history of hypertension). This association was maintained for the cumulative number of diagnoses of both systolic and diastolic hypertension. Conclusion The cumulative number of diagnoses of systolic or diastolic hypertension increases the risk of ESRD. Therefore, preventive treatment to avoid repetitive events of systolic or diastolic hypertension may be important to lower the risk of ESRD in this clinical population.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_4) ◽  
Author(s):  
Muhammad Khan ◽  
Muhammad U Khan ◽  
Muhammad Munir

Background: End stage renal disease (ESRD) is a well-recognized risk factor for development of sudden cardiac arrest(SCA). There is limited data on outcomes after an in-hospital SCA event in ESRD patients. Methods: Data were obtained from National Inpatient Sample from January 2007 to December 2017. In-hospital SCA was identified using International Classification of Disease, 9th Revision, Clinical Modification, and International Classification of Disease, 10th Revision, Clinical Modification codes of 99.60, 99.63, and 5A12012. ESRD patients were subsequently identified using codes of 585.6 and N18.6. Propensity -matched analysis using logistic regression with SD caliper of 0.2 was used to match patients with and without ESRD. Crude and propensity-matched (PS) cohorts outcomes were calculated. Results: A total of 1,412,985 patients sustained in-hospital SCA during our study period. ESRD patients with in-hospital SCA were younger and had a higher burden of key co-morbidities. Mortality was similar in ESRD and non-ESRD patients in PS matched cohort (70.4% vs. 70.7%, p = 0.45, figure 1) with an overall downward trend over our study years (figure 2). Conclusion: In the context of in-hospital SCA, mortality is similar in ESRD and non-ESRD patients in adjusted analysis. Adequate risk factor modification could further mitigate the risk of in-hospital SCA among ESRD patients


1997 ◽  
Vol 15 (4) ◽  
pp. 451-456 ◽  
Author(s):  
Thomas V. Perneger ◽  
Paul K. Whelton ◽  
Michael J. Klag

2007 ◽  
Vol 27 (5) ◽  
pp. 476-488 ◽  
Author(s):  
Bradley L. Urquhart ◽  
Andrew A. House

Elevated plasma total homocysteine (tHcy) is a risk factor for cardiovascular disease; however, in light of several recent randomized trials, the issue of causality has been cast into doubt. Patients with end-stage renal disease are particularly interesting as they consistently have elevated tHcy and their leading causes of morbidity and mortality are related to cardiovascular disease. In the present article, we review the early evidence for the homocysteine theory of atherosclerosis, homocysteine metabolism, mechanisms of toxicity, and pertinent available clinical investigations. Where appropriate, the sparse evidence of homocysteine in peritoneal dialysis is reviewed. We conclude by addressing the difficulties associated with lowering plasma tHcy in patients with end-stage renal disease and suggest some novel methods for lowering tHcy in this resistant population. Finally, to address the issue of causality, we recommend that clinicians and scientists await the results of the FAVORIT trial before abandoning homocysteine as a modifiable risk factor for cardiovascular disease, as this study has recruited patients from a population with consistently elevated plasma tHcy who are known to respond to vitamin therapy.


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