scholarly journals Some characteristics of the treatment of generalized and disseminated renal cell carcinoma

2004 ◽  
Vol 3 (2) ◽  
pp. 66-73
Author(s):  
O. V. Leonov ◽  
V. T. Dolgikh ◽  
V. I. Shirocorad ◽  
Ye. I. Kopyltsov ◽  
D. V. Dolgikh

In the article 206 treatment results of generalized and disseminated renal cell carcinoma are presented. It has been found that disseminated forms of hypernephroma required a combined surgical treatment without fail; nephrectomy added by adrenalectomy is recommended insuperpolar tumour localization. Combined surgery with resection or ablation of the affected organ seems to be advisable in disseminated renal cell carcinoma. Such an active surgical approach improves the prognosis. Medicamental antineoplastic therapy including immunotherapy in postoperative period can raise patients survivability and quality of life.

2019 ◽  
Vol 15 (2) ◽  
pp. 35-41
Author(s):  
Z. A. Yurmazov ◽  
N. A. Lushnikova ◽  
L. V. Spirina ◽  
E. A. Usynin ◽  
E. M. Slonimskaya ◽  
...  

The study objective is to evaluate the effectiveness of preoperative targeted therapy, spectrum and rate of adverse events, as well as quality of life in patients with bone metastases of renal cell carcinoma.Materials and methods. The study was conducted at the Research Institute of Oncology, Tomsk Medical Research Center between 2014 and 2018. The study included 34 patients with bone metastases of renal cell carcinoma who received preoperative targeted therapy with pazopanib for 8 weeks. All patients underwent surgical treatment of both the primary tumor and bone metastases.Results and conclusion. It was shown that preoperative targeted therapy is characterized by a high rate of clinical response and satisfactory tolerability. In some cases, preoperative targeted therapy improves the conditions for surgical treatment of metastatic bone lesions, decreases intraoperative blood loss, decreases the volume and duration of surgical intervention, which, in turn, allows to preserve bigger range of motion in the affected bone segment and improve patients’ quality of life.


2011 ◽  
Vol 29 (6) ◽  
pp. 593-605 ◽  
Author(s):  
Steven C. Ames ◽  
Alex S. Parker ◽  
Julia E. Crook ◽  
Nancy N. Diehl ◽  
Winston W. Tan ◽  
...  

2010 ◽  
Vol 106 (11) ◽  
pp. 1643-1647 ◽  
Author(s):  
Hideaki Miyake ◽  
Toshifumi Kurahashi ◽  
Kazuki Yamanaka ◽  
Yutaka Kondo ◽  
Atsushi Takenaka ◽  
...  

2006 ◽  
Vol 49 (2) ◽  
pp. 314-323 ◽  
Author(s):  
Wolfgang Dillenburg ◽  
Vassilis Poulakis ◽  
Konstantinos Skriapas ◽  
Rachelle de Vries ◽  
Nikolaos Ferakis ◽  
...  

Cancer ◽  
2021 ◽  
Author(s):  
Ridwan Alam ◽  
Hiten D. Patel ◽  
Zhuo T. Su ◽  
Joseph G. Cheaib ◽  
Yasser Ged ◽  
...  

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