scholarly journals Analysis of the combined effect of polymorphisms interferon genes OAS1, OAS3, PKR, IFNA17 and IFNG in susceptibility to chronic viral hepatitis C

2011 ◽  
Vol 10 (3) ◽  
pp. 19-23 ◽  
Author(s):  
V. A. Bychkov ◽  
N. V. Ryazantseva ◽  
V. V. Novitsky

Interferon system plays a key role in the antiviral response. Based on data from the literature, the most dangerous for the development of infectious diseases is the combination of risk alleles of several genes. This study focuses on the analysis of the combined effect of single nucleotide polymorphisms of interferon system genes OAS1, OAS3, PKR, IFNA17 and IFNG in the predisposition to chronic viral hepatitis C. It has been shown that the accounting of several risk genes improves the prediction of development of this disease.

2016 ◽  
Vol 2 (2) ◽  
pp. 59-68
Author(s):  
Anca Streinu-Cercel ◽  
Maria-Magdalena Moțoi ◽  
Alina Cristina Neguț ◽  
Luminița Bradu ◽  
Daniela Manolache ◽  
...  

2018 ◽  
Vol 35 (4) ◽  
pp. 661-666 ◽  
Author(s):  
Cristina Stasi ◽  
Caterina Silvestri ◽  
Roberto Berni ◽  
Maurizia Rossana Brunetto ◽  
Anna Linda Zignego ◽  
...  

Author(s):  
T. Ye. Makarova ◽  
◽  
N.N. Dudareva ◽  
N.N. Poletaeva ◽  
E.A. Medvedeva ◽  
...  

The problem of chronic viral hepatitis C currently remains relevant due to the high incidence, frequent outcomes in liver cirrhosis, high disability of the population, and expensive treatment. The article discusses timely approaches to the treatment of chronic viral hepatitis C, using interferon-free therapy regimens.


Author(s):  
ANARKAN SHABOLOTOVNA TASHPOLOTOVA ◽  
GULMIRA SAIBILDAEVNA SURANBAEVA ◽  
MYSKAL MAMAZIAEVNA ABDIKERIMOVA ◽  
ALTYNAI BORUBAEVNA MYRZAKULOVA ◽  
ANARA SHAMSHIDINOVNA DJUMAGULOVA ◽  
...  

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