scholarly journals Gene Drive: Can this be the Future of Agricultural Pest Management?

Author(s):  
Priyankar Mondal ◽  
Upasana Mohapatra ◽  
Moumi Ganguly
2021 ◽  
Author(s):  
Carol L. Goldsmith ◽  
Ki Eun Kang ◽  
Elizabeth Heitman ◽  
Zach N. Adelman ◽  
Leah W. Buchman ◽  
...  

2018 ◽  
Vol 115 (24) ◽  
pp. 6189-6194 ◽  
Author(s):  
Mohammad KaramiNejadRanjbar ◽  
Kolja N. Eckermann ◽  
Hassan M. M. Ahmed ◽  
Héctor M. Sánchez C. ◽  
Stefan Dippel ◽  
...  

The use of a site-specific homing-based gene drive for insect pest control has long been discussed, but the easy design of such systems has become possible only with the recent establishment of CRISPR/Cas9 technology. In this respect, novel targets for insect pest management are provided by new discoveries regarding sex determination. Here, we present a model for a suppression gene drive designed to cause an all-male population collapse in an agricultural pest insect. To evaluate the molecular details of such a sex conversion-based suppression gene drive experimentally, we implemented this strategy in Drosophila melanogaster to serve as a safe model organism. We generated a Cas9-based homing gene-drive element targeting the transformer gene and showed its high efficiency for sex conversion from females to males. However, nonhomologous end joining increased the rate of mutagenesis at the target site, which resulted in the emergence of drive-resistant alleles and therefore curbed the gene drive. This confirms previous studies that simple homing CRISPR/Cas9 gene-drive designs will be ineffective. Nevertheless, by performing population dynamics simulations using the parameters we obtained in D. melanogaster and by adjusting the model for the agricultural pest Ceratitis capitata, we were able to identify adequate modifications that could be successfully applied for the management of wild Mediterranean fruit fly populations using our proposed sex conversion-based suppression gene-drive strategy.


Insects ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 484
Author(s):  
Syed Arif Hussain Rizvi ◽  
Justin George ◽  
Gadi V. P. Reddy ◽  
Xinnian Zeng ◽  
Angel Guerrero

Since the first identification of the silkworm moth sex pheromone in 1959, significant research has been reported on identifying and unravelling the sex pheromone mechanisms of hundreds of insect species. In the past two decades, the number of research studies on new insect pheromones, pheromone biosynthesis, mode of action, peripheral olfactory and neural mechanisms, and their practical applications in Integrated Pest Management has increased dramatically. An interdisciplinary approach that uses the advances and new techniques in analytical chemistry, chemical ecology, neurophysiology, genetics, and evolutionary and molecular biology has helped us to better understand the pheromone perception mechanisms and its practical application in agricultural pest management. In this review, we present the most recent developments in pheromone research and its application in the past two decades.


1982 ◽  
Vol 30 (4) ◽  
pp. 601-618 ◽  
Author(s):  
Richard M. Feldman ◽  
Guy L. Curry

2018 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
hala mahfouz ◽  
Mawahab Mahmoud ◽  
Rasha Essam

2022 ◽  
pp. 129-155
Author(s):  
Graham Matthews ◽  
John Tunstall

Abstract This chapter focuses on the crop protection and pest management of cotton crops in Southern Africa (Eswatini, Zimbabwe, Zambia, Malawi, Mozambique, and Angola). It discusses how new technology will bring major changes in how cotton is grown in the future.


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