Can the neurophysiological effects of meditation inform the content of MBCT booster sessions for Bipolar Disorder? A Narrative Review of EEG Findings

OBJECTIVES: The objective of this article is to discuss the rationale/background for early intervention in bipolar disorder. METHOD: Narrative review. RESULTS: There are often significant delays before the diagnosis of bipolar disorder is made and effective management initiated. Growing evidence from both preclinical and clinical literature points to a clear need for improved early identification and early intervention in bipolar disorder. Increasing efforts are being applied to the identification of those at high risk of onset of bipolar disorder. It is hoped that identification of an early prodrome of illness will allow preventative measures to be taken. CONCLUSIONS: There is a clear rationale for improved early identification and early intervention in bipolar disorder.

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Evaluation and treatment of older-age bipolar disorder: a narrative review

Drugs in Context ◽

10.7573/dic.2021-1-8 ◽

2021 ◽

Vol 10 ◽

pp. 1-12

Author(s):

Rajesh R Tampi ◽

Pallavi Joshi ◽

Gargi Bhattacharya ◽

Sheila Gupta

Keyword(s):

Bipolar Disorder ◽

Narrative Review ◽

Older Age

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Longitudinal changes in the antecedent and early manifest course of bipolar disorder—A narrative review of prospective studies

Australian & New Zealand Journal of Psychiatry ◽

10.1177/0004867417700730 ◽

2017 ◽

Vol 51 (5) ◽

pp. 509-523 ◽

Cited By ~ 14

Author(s):

Andrea Pfennig ◽

Karolina Leopold ◽

Philipp Ritter ◽

Anne Böhme ◽

Emanuel Severus ◽

...

Keyword(s):

Risk Factors ◽

Bipolar Disorder ◽

Prospective Study ◽

Potential Risk ◽

Prospective Studies ◽

Bipolar Disorders ◽

Childhood Anxiety ◽

Narrative Review ◽

Character Traits ◽

Potential Risk Factors

Objective: Prospective study designs ideally allow patients to be followed from the first manifestations of the illness or even from an at-risk stage. It can thus provide data on the predictive value of changes in clinical symptomatology, cognition or further biological markers to broaden our understanding of the etiopathology and symptomatic trajectory of bipolar disorders. The scope of this narrative review is to summarize evidence from prospectively collected data on psychopathological and other clinical and biological changes in the early developmental course of bipolar disorders. Methods: The narrative review was based on a literature search conducted in February 2016 within the PubMed library for prospective study data of persons in antecedent and early manifest stages of manifest bipolar disorder published within the last 15 years. Results: A total of 19 prospective studies were included. Regarding psychopathological features; personality, temperament and character traits as well as changes in sleep and circadian rhythm, the evidence suggests that risk factors for the development of bipolar disorder can already be described and should be studied further to understand their interaction, mediation with other factors and timing in the developmental process of bipolar disorder. Apart from the positive family history, childhood anxiety, sleep problems, subthreshold (hypo)manic symptoms and certain character traits/emotionality should be identified and monitored already in clinical practice as their presence likely increases risk of bipolar disorder. Up to date no substantiated evidence was found from prospective studies addressing cognitive features, life events, immunological parameters and morphological central nervous system changes as potential risk factors for bipolar disorder. Conclusion: For an improved understanding of episodic disorders, longitudinal data collection is essential. Since the etiology of bipolar disorders is complex, a number of potential risk factors have been proposed. Prospective studies addressing this spectrum and resilience factors are critical and will be best conducted within multi-site research networks or initiatives.

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