scholarly journals Prevention of postoperative pulmonary complications after esophageal cancer surgery

2019 ◽  
Vol 11 (S9) ◽  
pp. S1143-S1144
Author(s):  
Francisco Schlottmann ◽  
Marco G. Patti
Keyword(s):  
Esophageal Cancer ◽  
Pulmonary Complications ◽  
Cancer Surgery ◽  
Postoperative Pulmonary Complications ◽  
Esophageal Cancer Surgery

P40 CONDITIONAL SURVIVAL AFTER CURATIVE TREATMENT OF ESOPHAGEAL CANCER

2019 ◽  
Vol 32 (Supplement_2) ◽  
Author(s):  
E R C Hagens ◽  
M L Feenstra BSc ◽  
M I van Berge Henegouwen ◽  
W J Eshuis ◽  
M C C M Hulshof ◽  
...  
Keyword(s):  
Overall Survival ◽  
Esophageal Cancer ◽  
Neoadjuvant Chemoradiation ◽  
Pulmonary Complications ◽  
Cancer Surgery ◽  
Conditional Survival ◽  
Probability Of Survival ◽  
Esophageal Cancer Surgery ◽  
C Statistic

Abstract Aim To assess conditional survival and design a nomogram predicting the conditional probability of survival for esophageal cancer patients after surgery. Background and methods Conditional survival accounts for the time already survived after surgery and may be informative in addition to conventional static survival estimates during follow-up. Consecutive patients with esophageal cancer who received neoadjuvant chemoradiation followed by an esophagectomy between January 2004 and 2019 in the Amsterdam UMC, The Netherlands were included. Conditional survival was defined as the probability of surviving “y” years after already surviving for “x” years. Cox proportional hazard models were used to evaluate predictors for overall survival. A nomogram was constructed to predict 5-year survival correcting for time already survived. Results 660 patients were included in this study. The median overall survival was 46.4 months (95%CI 39.1–53.8). The probability to achieve 5-year overall survival after resection increased from 46% directly after surgery to 55%, 67%, 79% and 88% per additional year survived. ypN-stage was the strongest predictor for overall survival (HR6.50, p<0.001, for ypN3 with ypN0 as reference), followed by pulmonary complications (HR1.16, p=0.002), cardiac comorbidity (HR1.27, p=0.040) and ypT-stage (HR1.461, p=0.039 for ypT2-3 with ypT0 as reference). These variables were included in the nomogram (figure 1), which predicts survival with a C-statistic of 0.70. Conclusion The proposed nomogram showed an accurate prediction of survival in patients after esophageal cancer surgery, taking the years already survived after surgery into account. This nomogram can be helpful in counselling patients in the follow-up after esophageal cancer surgery.

scholarly journals Safety of Esophageal Cancer Surgery During the First Wave of the COVID-19 Pandemic in Europe: A Multicenter Study

2021 ◽  
Author(s):  
Alexander B. J. Borgstein ◽  
Stefanie Brunner ◽  
Masaru Hayami ◽  
Johnny Moons ◽  
Hans Fuchs ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Esophageal Cancer ◽  
Respiratory Failure ◽  
Multicenter Study ◽  
Pulmonary Complications ◽  
Cancer Surgery ◽  
Screening Methods ◽  
Preoperative Screening ◽  
Control Cohort ◽  
Esophageal Cancer Surgery

Abstract Background Many hospitals postponed elective surgical care during the first wave of the coronavirus disease 2019 (COVID-19) pandemic. Some centers continued elective surgery, including esophageal cancer surgery, with the use of preoperative screening methods; however, there is no evidence supporting the safety of this strategy as postoperative outcomes after esophageal cancer surgery during the COVID-19 pandemic have not yet been investigated. Methods This multicenter study in four European tertiary esophageal cancer referral centers included consecutive adult patients undergoing elective esophageal cancer surgery from a prospectively maintained database in a COVID-19 pandemic cohort (1 March 2020–31 May 2020) and a control cohort (1 October 2019–29 February 2020). The primary outcome was the rate of respiratory failure requiring mechanical ventilation. Results The COVID-19 cohort consisted of 139 patients, versus 168 patients in the control cohort. There was no difference in the rate of respiratory failure requiring mechanical ventilation (13.7% vs. 8.3%, p = 0.127) and number of pulmonary complications (32.4% vs. 29.9%, p = 0.646) between the COVID-19 cohort and the control cohort. Overall, postoperative morbidity and mortality rates were comparable between both cohorts. History taking and reverse transcription polymerase chain reaction (RT-PCR) were used as preoperative screening methods to detect a possible severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in all centers. No patients were diagnosed with COVID-19 pre- or postoperatively. Conclusion Esophageal cancer surgery during the first wave of the COVID-19 pandemic was not associated with an increase in pulmonary complications as no patients were diagnosed with COVID-19. Esophageal cancer surgery can be performed safely with the use of adequate preoperative SARS-CoV-2 screening methods.

Risk stratification of anastomotic leakage using eGFR and FIB-4 index in patients undergoing esophageal cancer surgery

2021 ◽  
Author(s):  
Keita Takahashi ◽  
Katsunori Nishikawa ◽  
Yuichiro Tanishima ◽  
Yoshitaka Ishikawa ◽  
Takahiro Masuda ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Risk Stratification ◽  
Anastomotic Leakage ◽  
Cancer Surgery ◽  
Esophageal Cancer Surgery

Volume and outcomes after esophageal cancer surgery: the experience of the Region of Lombardy—Italy

2013 ◽  
Vol 65 (4) ◽  
pp. 271-275 ◽  
Author(s):  
Uberto Fumagalli ◽  
Maurizio Bersani ◽  
Antonio Russo ◽  
Alessandra Melis ◽  
Stefano de Pascale ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Cancer Surgery ◽  
Esophageal Cancer Surgery

Esophageal Cancer Surgery in Heart Transplant Patients

2005 ◽  
Vol 80 (4) ◽  
pp. 1510-1512 ◽  
Author(s):  
Burkhard H.A. von Rahden ◽  
Hubert J. Stein ◽  
Georg Schmidt ◽  
Holger Bartels ◽  
Matthias Overbeck ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Heart Transplant ◽  
Cancer Surgery ◽  
Transplant Patients ◽  
Esophageal Cancer Surgery
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