scholarly journals Partial orchiectomy vs. radical orchiectomy for pediatric testis tumors

2020 ◽  
Vol 9 (5) ◽  
pp. 2400-2407
Author(s):  
Lynn L. Woo ◽  
Jonathan H. Ross
Keyword(s):  
Radical Orchiectomy ◽  
Partial Orchiectomy ◽  
Testis Tumors

scholarly journals Three primary testicular tumours: Trials and tribulations of testicular preservation

2013 ◽  
Vol 7 (9-10) ◽  
pp. 630 ◽  
Author(s):  
Connor M Forbes ◽  
Charles Metcalfe ◽  
Nevin Murray ◽  
Peter C Black
Keyword(s):  
Side Effects ◽  
Male Patient ◽  
Patient Preference ◽  
Young Male ◽  
Recurrence Risk ◽  
Testicular Neoplasms ◽  
Testis Cancer ◽  
Testicular Tumours ◽  
Radical Orchiectomy ◽  
Partial Orchiectomy

Balancing recurrence risk, side effects and patient preference in the treatment of multiple metachronous testicular tumours can be challenging. We present the case of a young male patient who developed 3 different primary testicular neoplasms over an 8-year period, each associated with retroperitoneal lymphadenopathy requiring chemotherapy. The first tumour at age 19 was managed with radical orchiectomy. Four years later, a partial orchiectomy was performed to remove 2 small lesions. Another 4 years later, a complete orchiectomy was required for an additional tumour. This case highlights the caveats of testis-sparing surgery for testis cancer and the need for careful surveillance in these patients.

Paternity in men with stage I testis tumors on surveillance.

1998 ◽  
Vol 16 (2) ◽  
pp. 733-734 ◽  
Author(s):  
H W Herr ◽  
N Bar-Chama ◽  
M O'Sullivan ◽  
P C Sogani
Keyword(s):  
Clinical Stage ◽  
Germ Cell Tumors ◽  
Stage I ◽  
Retroperitoneal Lymph Node Dissection ◽  
Nerve Sparing ◽  
Testis Tumor ◽  
Fertility Potential ◽  
Testis Tumors ◽  
Nonseminomatous Germ Cell Tumors

PURPOSE We report long-term paternity in men with stage I testis tumors who were managed initially by surveillance. PATIENTS AND METHODS One hundred five patients with clinical stage I nonseminomatous germ cell tumors of the testis were entered on a surveillance protocol and followed up for more than 10 years. Actual fertility potential was assessed by pregnancy. RESULTS Of the 105 patients, 41 (39%) have fathered children, which includes 36 of 78 (46%) patients while on active surveillance and five of 27 (19%) patients after treatment for relapse. Of 63 couples who attempted a pregnancy on surveillance or were presumed capable of impregnation (whether they tried or not), 41 (65%) were successful. CONCLUSION These results show that the majority of men with stage I testis tumor who are on surveillance after orchiectomy, have a suitable partner, and attempt impregnation achieve a successful pregnancy. Pregnancy rates appear to be less than reported in men who have a nerve-sparing retroperitoneal lymph node dissection (RPLND) because more patients on surveillance require treatment for relapse, which reduces their chances for pregnancy.

scholarly journals Neuroendocrine Testicular Tumors: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 10 (1) ◽  
pp. 15-25 ◽  
Author(s):  
Mseddi M. Amine ◽  
Bouzguenda Mohamed ◽  
Hadjslimane Mourad ◽  
Hamza Majed ◽  
Charfi Slim ◽  
...  
Keyword(s):  
Survival Rate ◽  
Neuroendocrine Tumors ◽  
Carcinoid Syndrome ◽  
Case Reports ◽  
Meta Analysis ◽  
Case Series ◽  
Palpable Mass ◽  
Pubmed Database ◽  
Evolutionary Features ◽  
Radical Orchiectomy

Purpose: The purpose of this study is to study the main epidemiological, clinical, para clinical, pathological, therapeutic, and evolutionary features of patients with testicular neuroendocrine tumors (TNET). Materials and Methods: Nine case series and sixteen case reports were identified by searching PubMed database and qualified for inclusion in this study. We added the data of one case treated in the department of urology in Habib Bourguiba Hospital in Sfax, to the published cases. Results: A total of 132 cases were collected. Median age at diagnosis was 39 years old (range 10- 83 years). The most common presenting symptom was either a testicular mass or a swelling in 38.46% of cases. Carcinoid syndrome was documented in 10.60% of patients. The clinical examination revealed a palpable mass in 44.70% of patients. This mass was painless and firm in most cases. Serum tumor markers (β-gonadotrophine chorionique humaine, α-feto protein, and lactate dehydrogenase) were within normal limits in all patients except in one case. Most testicular neuroendocrine tumors (76.52%) were primary and pure. The tumors were positive for chromogranin (100%), synaptophysin (100%) and cytokeratin (93.10%). Metastases were detected at time of diagnosis in eight cases (6.06%). The main treatment was radical orchiectomy performed in 127 patients (96.21%). The 5-year overall survival rate was 78.70% and the 5-year specific survival rate was 84.30%. Conclusion: The diagnosis of testicular carcinoids is based on the immunohistochemistry study. The treatment of choice for these tumors is radical orchiectomy. Somatostatin analogues were reported to be effective in patients with carcinoid syndrome.

scholarly journals PROGNOSTIC FACTORS IN THE COMMON TESTIS TUMORS

1968 ◽  
Vol 103 (4) ◽  
pp. 827-836 ◽  
Author(s):  
SAMUEL S. KUROHARA ◽  
AHMED O. BADIB ◽  
JOHN H. WEBSTER ◽  
LEONARD S. J. MARTIN ◽  
MARVIN W. WOODRUFF
Keyword(s):  
Prognostic Factors ◽  
The Common ◽  
Testis Tumors

scholarly journals Paraneoplastic Autoimmunity Associated with Testicular Myeloid Sarcoma and Chronic Myelomonocytic Leukemia

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Jeffrey W. Craig ◽  
Richard J. Lin
Keyword(s):  
Mass Effect ◽  
Hematologic Malignancies ◽  
Chronic Myelomonocytic Leukemia ◽  
Myeloid Sarcoma ◽  
Malignant Neoplasms ◽  
Presenting Symptoms ◽  
Immature Myeloid Cells ◽  
Disease Entities ◽  
Radical Orchiectomy ◽  
Myelomonocytic Leukemia

Myeloid sarcomas are rare extramedullary solid tumors composed of immature myeloid cells. The clinical presentations of these malignant neoplasms are highly variable, ranging from asymptomatic to localized mass effect. Here, we report an unusual case of myeloid sarcoma of the testis found in association with chronic myelomonocytic leukemia where the presenting symptoms were autoimmune pericarditis and migratory arthralgias and myalgias that preceded testicular enlargement by nearly three months. Treatment with both radical orchiectomy and leukemia-directed chemotherapy led to immediate reductions in symptom severity, suggesting that these early symptoms were paraneoplastic in origin. Review of the literature identified the association between hematological malignancies, including chronic myelomonocytic leukemia, and paraneoplastic autoimmune phenomena with features similar to polymyalgia rheumatica and rheumatoid arthritis. Importantly, rheumatologic symptoms related to these disease entities may be easily dismissed as vague or unrelated complaints or treated as purely rheumatologic conditions, thus delaying the formal diagnoses. Clinicians must recognize the common association between possible paraneoplastic rheumatologic symptoms and hematologic malignancies such as chronic myelomonocytic leukemia.

scholarly journals An 81-year-old patient with recent diagnosis of classic testicular seminoma

2016 ◽  
Vol 10 (2) ◽  
pp. 143
Author(s):  
Sandro José Martins ◽  
José Carlos De Almeida ◽  
Vitorino Modesto Dos Santos ◽  
Ana Carolina Vieira Cançado ◽  
Giovanna Ferraz Cavalcanti ◽  
...  
Keyword(s):  
Early Stage ◽  
Testicular Tumor ◽  
Population Based ◽  
Medical Attention ◽  
Left Testis ◽  
Testicular Seminoma ◽  
Left Testicle ◽  
First Choice ◽  
Recent Diagnosis ◽  
Radical Orchiectomy

An old patient with recent diagnosis of classic seminoma is reported. The tumor of left testicle was heralded by tenderness about 30 days before medical attention and enlarged testis confirmation. There was antecedent of left testis hypotrophy treated with testosterone and a surgery for varicocele at 15 years of age. Clinical hypothesis of testicular tumor was strengthened by ultrasonography images and elevated tumor markers (lactate dehydrogenase, <span>α</span>-fetoprotein, and <span>β</span>-hCG). Radical orchiectomy was performed and a classic seminoma (pT1pNx) was diagnosed. Active waiting was the first choice for management, but six months later a retroperitoneal mass with lymph node enlargement were found, and he underwent four sessions of carboplatin (AUC 5), bleomycin and etoposide (BEP regimen). Asymptomatic, he was referred to outpatient surveillance on Oncology. Population-based studies about frequency and outcome of early-stage testis seminoma in elderly are scarce. Case studies might contribute to the knowledge about this condition.

The Surgical Management of Testis Tumors

1971 ◽  
Vol 106 (1) ◽  
pp. 84-93 ◽  
Author(s):  
Donald G. Skinner ◽  
Wyland F. Leadbetter
Keyword(s):  
Surgical Management ◽  
Testis Tumors
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