Take Care with Type C: Serious Considerations in the Selection of Patients with Hepatitis C for Total Joint Arthroplasty

2015 ◽  
Vol 97 (23) ◽  
pp. e77-1-2
Author(s):  
Pooya Javidan ◽  
Richard H Walker
Keyword(s):  
Hepatitis C ◽  
Total Joint Arthroplasty ◽  
Joint Arthroplasty ◽  
Type C ◽  
Selection Of Patients ◽  
Selection Of

Early non-invasive selection of patients at high risk of severe hepatitis C recurrence after liver transplantation

2016 ◽  
Vol 18 (3) ◽  
pp. 471-479 ◽  
Author(s):  
G. Crespo ◽  
M. Gambato ◽  
O. Millán ◽  
G. Casals ◽  
P. Ruiz ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C ◽  
High Risk ◽  
Severe Hepatitis ◽  
Non Invasive ◽  
Hepatitis C Recurrence ◽  
Selection Of Patients ◽  
Selection Of

scholarly journals Coinfection of HIV and hepatitis C increases complication rates after total joint arthroplasty

SICOT-J ◽  
2020 ◽  
Vol 6 ◽  
pp. 37
Author(s):  
Christopher Fang ◽  
Ella Cornell ◽  
Quinten Dicken ◽  
David Freccero ◽  
David Mattingly ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Total Joint Arthroplasty ◽  
Complication Rate ◽  
Joint Arthroplasty ◽  
Complication Rates ◽  
Orthopaedic Care ◽  
History Of ◽  
Unique Outcome ◽  
Hcv Coinfection ◽  
Iv Drug Use

Introduction: As advances in efficacy of human immunodeficiency virus (HIV) and hepatitis-C virus (HCV) anti-viral medications increase, patients are able to maintain higher quality of lives than ever before. While these patients live longer lives, the unique patient population of those co-infected with both HIV and HCV increases. As these older patients seek orthopaedic care, it is important to understand their unique outcome profile. The purpose of this study was to evaluate the complication rate after total joint arthroplasty (TJA) in patients with HIV and HCV coinfection compared with patients with HIV or HCV only. Methods: A retrospective review of patients undergoing primary total joint arthroplasty (TJA) at our urban, academic hospital between April 2016 and April 2019 was conducted. Patients were stratified into three groups according to viral status: HIV only, HCV only, or HIV and HCV coinfection. Baseline demographics, intravenous drug (IV) use, surgery type, CD4+ count, follow-up and complications were analysed. Results: Of the 133 patients included in the study, 28 had HIV, 88 had HCV and 17 were coinfected with both HIV and HCV. Coinfected patients were more likely to have a lower BMI (p < 0.039) and a history of IV drug use (p < 0.018) compared to patients with either HIV or HCV only. Coinfected patients had a higher complication rate (41%) than both HIV only (7%; p < 0.001) and HCV only (12.5%; p < 0.001) patients. Discussion: Patients coinfected with HIV and HCV undergoing TJA have a higher complication rate than patients with either infection alone. As this unique population of coinfected patients continues to expand, increasingly they will be under the care of arthroplasty surgeons. Improved awareness and understanding of the baseline demographic differences between these patients is paramount. Recognition of the increased complication rates grants the opportunity to improve their orthopaedic care through preoperative and multidisciplinary management.

Does the hepatitis C virus affect the outcomes of total joint arthroplasty? A meta-analysis of ten studies

2019 ◽  
Vol 24 (5) ◽  
pp. 822-829 ◽  
Author(s):  
Wuzeng Wei ◽  
Tianshen Liu ◽  
Jie Zhao ◽  
Bing Li ◽  
Shuai LI ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Total Joint Arthroplasty ◽  
Meta Analysis ◽  
Joint Arthroplasty

The Impact of Hepatitis C on Short-Term Outcomes of Total Joint Arthroplasty

2015 ◽  
Vol 97 (23) ◽  
pp. 1952-1957 ◽  
Author(s):  
Kimona Issa ◽  
Matthew R Boylan ◽  
Qais Naziri ◽  
Dean C Perfetti ◽  
Aditya V Maheshwari ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Total Joint Arthroplasty ◽  
Joint Arthroplasty ◽  
Short Term ◽  
The Impact

Neuraxial anesthesia is associated with improved survival after total joint arthroplasty depending on frailty: a cohort study

2020 ◽  
Vol 45 (6) ◽  
pp. 405-411 ◽  
Author(s):  
Rebecca L Johnson ◽  
Ryan D Frank ◽  
Elizabeth B Habermann ◽  
Alanna M Chamberlain ◽  
Matthew P Abdel ◽  
...  
Keyword(s):  
Cohort Study ◽  
Total Joint Arthroplasty ◽  
Cox Regression ◽  
Joint Arthroplasty ◽  
Neuraxial Anesthesia ◽  
Wound Complications ◽  
Neuraxial Block ◽  
Frailty Status ◽  
Vulnerable Patients ◽  
Selection Of

BackgroundFrailty increases risk for complications after total joint arthroplasty (TJA). Whether this association is influenced by anesthetic administered is unknown. We hypothesized that use of neuraxial (spinal or epidural) anesthesia is associated with better outcomes compared with general anesthesia, and that the effect of anesthesia type on outcomes differs by frailty status.MethodsThis single-institution cohort study included all patients (≥50 years) from January 2005 through December 2016 undergoing unilateral, primary and revision TJA. Using multivariable Cox regression, we assessed relationships between anesthesia type, a preoperative frailty deficit index (FI) categorized as non-frail (FI <0.11), vulnerable (FI 0.11 to 0.20), and frail (FI >0.20), and complications (mortality, infection, wound complications/hematoma, reoperation, dislocation, and periprosthetic fracture) within 1 year after surgery. Interactions between anesthesia type and frailty were tested, and stratified models were presented when an interaction (p<0.1) was observed.ResultsAmong 18 458 patients undergoing TJA, more patients were classified as frail (21.5%) and vulnerable (36.2%) than non-frail (42.3%). Anesthesia type was not associated with complications after adjusting for age, joint, and revision type. However, in analyzes stratified by frailty, vulnerable patients under neuraxial block had less mortality (HR=0.49; 95% CI 0.27 to 0.89) and wound complications/hematoma (HR=0.71; 95% CI 0.55 to 0.90), whereas no difference in risk by anesthesia type was observed among patients found non-frail or frail.ConclusionsNeuraxial anesthesia use among vulnerable patients was associated with improved survival and less wound complications. Calculating preoperative frailty prior to TJA informs perioperative risk and enhances shared-decision making for selection of anesthesia type.

Total Joint Arthroplasty in Patients with Hepatitis C

2010 ◽  
Vol 25 (3) ◽  
pp. e50
Author(s):  
Wadih Y. Matar ◽  
Aidin Eslampour ◽  
S. Mehdi Jafari ◽  
Javad Parvizi
Keyword(s):  
Hepatitis C ◽  
Total Joint Arthroplasty ◽  
Joint Arthroplasty

Undetectable Hepatitis C Viral Load Is Associated With Improved Outcomes Following Total Joint Arthroplasty

2019 ◽  
Vol 34 (12) ◽  
pp. 2890-2897 ◽  
Author(s):  
David Novikov ◽  
James E. Feng ◽  
Afshin A. Anoushiravani ◽  
Jonathan M. Vigdorchik ◽  
Claudette M. Lajam ◽  
...  
Keyword(s):  
Viral Load ◽  
Hepatitis C ◽  
Total Joint Arthroplasty ◽  
Joint Arthroplasty ◽  
Improved Outcomes
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