Abstract P-7: Cryoelectron Microscopy Study of Water-Soluble Extracellular Domain of α7 Nicotinic Acetylcholine Receptor

Extracellular Domain ◽

Microscopy Study ◽

Water Soluble ◽

Cryoelectron Microscopy ◽

Design and expression of human α7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ◽

10.1016/j.bbapap.2008.11.002 ◽

2009 ◽

Vol 1794 (2) ◽

pp. 355-366 ◽

Cited By ~ 15

Author(s):

Marios Zouridakis ◽

Paraskevi Zisimopoulou ◽

Elias Eliopoulos ◽

Konstantinos Poulas ◽

Socrates J. Tzartos

Keyword(s):

Ligand Binding ◽

Acetylcholine Receptor ◽

Extracellular Domain ◽

Binding Properties ◽

Nicotinic Acetylcholine ◽

Enhanced Solubility

N-Stearoylethanolamine protects the brain and improves memory of mice treated with lipopolysaccharide or immunized with the extracellular domain of α7 nicotinic acetylcholine receptor

International Immunopharmacology ◽

10.1016/j.intimp.2017.09.023 ◽

2017 ◽

Vol 52 ◽

pp. 290-296 ◽

Cited By ~ 9

Author(s):

Olena Lykhmus ◽

Kateryna Uspenska ◽

Lyudmyla Koval ◽

Daria Lytovchenko ◽

Larysa Voytenko ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Extracellular Domain ◽

Nicotinic Acetylcholine ◽

The Brain

Localization by site-directed mutagenesis of a galantamine binding site on α7 nicotinic acetylcholine receptor extracellular domain

Journal of Receptors and Signal Transduction ◽

10.3109/10799893.2010.505239 ◽

2010 ◽

Vol 30 (6) ◽

pp. 469-483 ◽

Cited By ~ 16

Author(s):

Jürgen Ludwig ◽

Anja Höffle-Maas ◽

Marek Samochocki ◽

Edgar Luttmann ◽

Edson X. Albuquerque ◽

...

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Extracellular Domain ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Refolding of the Escherichia coli expressed extracellular domain of α7 nicotinic acetylcholine receptor

European Journal of Biochemistry ◽

10.1046/j.1432-1033.2002.02961.x ◽

2002 ◽

Vol 269 (11) ◽

pp. 2801-2809 ◽

Cited By ~ 15

Author(s):

Victor I. Tsetlin ◽

Natalia I. Dergousova ◽

Ekaterina A. Azeeva ◽

Elena V. Kryukova ◽

Irina A. Kudelina ◽

...

Keyword(s):

Escherichia Coli ◽

Acetylcholine Receptor ◽

Extracellular Domain ◽

The role of carbohydrate component of recombinant α7 nicotinic acetylcholine receptor extracellular domain in its immunogenicity and functional effects of resulting antibodies

Immunobiology ◽

10.1016/j.imbio.2016.07.012 ◽

2016 ◽

Vol 221 (12) ◽

pp. 1355-1361 ◽

Cited By ~ 3

Author(s):

Olena Lykhmus ◽

Lyudmyla Koval ◽

Dar’ya Pastuhova ◽

Marios Zouridakis ◽

Socrates Tzartos ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Extracellular Domain ◽

Carbohydrate Component ◽

Insights from modelling the 3D structure of the extracellular domain of α7 nicotinic acetylcholine receptor

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2004.05.016 ◽

2004 ◽

Vol 319 (2) ◽

pp. 433-438 ◽

Cited By ~ 94

Author(s):

Kuo-Chen Chou

Keyword(s):

Acetylcholine Receptor ◽

3D Structure ◽

Extracellular Domain ◽

Activation of α7 nicotinic acetylcholine receptor alleviates cerebral cortical neuron injury induced by oxygen-glucose deprivation

Academic Journal of Second Military Medical University ◽

10.3724/sp.j.1008.2015.00472 ◽

2015 ◽

Vol 36 (5) ◽

pp. 472

Author(s):

Ru-juan XIN ◽

Ting ZHAO ◽

Min NI ◽

Dong-jie LI ◽

Fu-ming SHEN

Keyword(s):

Cortical Neuron ◽

Acetylcholine Receptor ◽

Glucose Deprivation ◽

Oxygen Glucose Deprivation ◽

Nicotinic Acetylcholine ◽

Cerebral Cortical Neuron ◽

Neuron Injury

Discovery of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor: Scaffold hopping approach

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113189 ◽

2021 ◽

Vol 214 ◽

pp. 113189

Author(s):

István Ledneczki ◽

Pál Tapolcsányi ◽

Eszter Gábor ◽

András Visegrády ◽

Márton Vass ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Allosteric Modulators ◽

Scaffold Hopping ◽

Nicotinic Acetylcholine ◽

Positive Allosteric Modulators

Retracted : Role of α7‐nicotinic acetylcholine receptor in human non‐small cell lung cancer proliferation

Cell Proliferation ◽

10.1111/j.1365-2184.2008.00566.x ◽

2008 ◽

Vol 41 (6) ◽

pp. 936-959 ◽

Cited By ~ 57

Author(s):

L. Paleari ◽

A. Catassi ◽

M. Ciarlo ◽

Z. Cavalieri ◽

C. Bruzzo ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Acetylcholine Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Cancer Proliferation ◽

Nicotine Accelerates Atherosclerosis in Apolipoprotein E–Deficient Mice by Activating α7 Nicotinic Acetylcholine Receptor on Mast Cells

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.116.307264 ◽

2017 ◽

Vol 37 (1) ◽

pp. 53-65 ◽

Cited By ~ 27

Author(s):

Chen Wang ◽

Han Chen ◽

Wei Zhu ◽

Yinchuan Xu ◽

Mingfei Liu ◽

...

Keyword(s):

Mast Cells ◽

Apolipoprotein E ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Deficient Mice