scholarly journals High performance liquid chromatography of fluorescein isothiocyanate isomers and intermediate products.

1985 ◽  
Vol 1 (5) ◽  
pp. 447-450 ◽  
Author(s):  
Koji MURAMOTO ◽  
Hisao KAMIYA ◽  
Hiroshi KAWAUCHI ◽  
Hiroshi MEGURO
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Fluorescein Isothiocyanate ◽  
Intermediate Products

scholarly journals Application of high-performance liquid chromatography in porphyrias diagnostics

2021 ◽  
Vol 20 (3) ◽  
pp. 140-144
Author(s):  
А. I. Puzikova ◽  
Е. А. Litvin ◽  
D. А. Kildyushkin ◽  
А. Е. Druy
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Clinical Manifestations ◽  
Chromatography Method ◽  
Intermediate Products ◽  
Heme Synthesis ◽  
Timely Diagnosis ◽  
Liquid Chromatography Method

Porphyrias are distinguished by the stage of heme synthesis at which a failure occurs, leading to the accumulation of intermediate products – porphyrins. Due to the low specificity of clinical manifestations of porphyria and the latent course of the disease, their timely diagnosis is difficult. This article substantiates the effectiveness of high-performance liquid chromatography method in the determination of porphyrins. The method is suitable for porphyrin determination in urine, blood and feces of patients. Examples of its work are shown.

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