scholarly journals The effect of information on prostate cancer screening decision process: A discrete choice experiment

2019 ◽  
Author(s):  
Maud Charvin ◽  
Guy Launoy ◽  
Célia Berchi
Keyword(s):  
Prostate Cancer ◽  
Cancer Screening ◽  
Discrete Choice ◽  
Choice Model ◽  
Prostate Cancer Screening ◽  
False Negative ◽  
Informed Choice ◽  
Negative Results ◽  
False Negative Results ◽  
History Of

Abstract Background: Prostate cancer screening is controversial because of uncertainty about its benefits and risks. The aim of this survey was to reveal preferences of men concerning prostate cancer screening and to test the effect of an informative video on these preferences. Methods: A stated preferences questionnaire was sent by e-mail to men aged 50-75 with no history of prostate cancer. Half of them were randomly assigned to view an informative video. A discrete choice model was established to reveal men’s preferences for six prostate cancer screening characteristics: mortality by prostate cancer, number of false positive and false negative results, number of overdiagnosis, out-of-pocket costs and recommended frequency. Results: 1024 men representative of the French general population filled in the entire questionnaire. Each attribute gave the expected sign except for overdiagnosis. The video seemed to increase the intention to abstain from prostate cancer screening. Conclusions: The participants attached greater importance to a decrease in the number of false negatives and a reduction in prostate cancer mortality than to other risks such as the number of false positives and overdiagnosis. Further research is needed to help men make an informed choice regarding screening.

scholarly journals The effect of information on prostate cancer screening decision process: a discrete choice experiment

2020 ◽  
Author(s):  
Maud Charvin ◽  
Guy Launoy ◽  
Célia Berchi
Keyword(s):  
Prostate Cancer ◽  
Cancer Screening ◽  
Discrete Choice ◽  
Choice Model ◽  
Prostate Cancer Screening ◽  
False Negative ◽  
Informed Choice ◽  
Negative Results ◽  
False Negative Results ◽  
History Of

Abstract Background: Prostate cancer screening is controversial because of uncertainty about its benefits and risks. The aim of this survey was to reveal preferences of men concerning prostate cancer screening and to test the effect of an informative video on these preferences. Methods: A stated preferences questionnaire was sent by e-mail to men aged 50-75 with no history of prostate cancer. Half of them were randomly assigned to view an informative video. A discrete choice model was established to reveal men’s preferences for six prostate cancer screening characteristics: mortality by prostate cancer, number of false positive and false negative results, number of overdiagnosis, out-of-pocket costs and recommended frequency. Results: 1024 men representative of the French general population filled in the entire questionnaire. Each attribute gave the expected sign except for overdiagnosis. The video seemed to increase the intention to abstain from prostate cancer screening. Conclusions: The participants attached greater importance to a decrease in the number of false negatives and a reduction in prostate cancer mortality than to other risks such as the number of false positives and overdiagnosis. Further research is needed to help men make an informed choice regarding screening.

scholarly journals The effect of information on prostate cancer screening decision process: A discrete choice experiment

2020 ◽  
Author(s):  
Maud Charvin ◽  
Guy Launoy ◽  
Célia Berchi
Keyword(s):  
Prostate Cancer ◽  
Cancer Screening ◽  
Discrete Choice ◽  
Choice Model ◽  
Prostate Cancer Screening ◽  
False Negative ◽  
Informed Choice ◽  
Population Based ◽  
Negative Results ◽  
False Negative Results

Abstract Background: Prostate cancer screening is controversial because of uncertainty about its benefits and risks. The aim of this survey was to reveal preferences of men concerning prostate cancer screening and to test the effect of an informative video on these preferences. Methods: A stated preferences questionnaire was sent by e-mail to men aged 50-75 with no history of prostate cancer. Half of them were randomly assigned to view an informative video. A discrete choice model was established to reveal men’s preferences for six prostate cancer screening characteristics: mortality by prostate cancer, number of false positive and false negative results, number of overdiagnosis, out-of-pocket costs and recommended frequency. Results: A population-based sample composed by 1024 men representative of the French general population filled in the entire questionnaire. Each attribute gave the expected sign except for overdiagnosis. The video seemed to increase the intention to abstain from prostate cancer screening.Conclusions: The participants attached greater importance to a decrease in the number of false negatives and a reduction in prostate cancer mortality than to other risks such as the number of false positives and overdiagnosis. Further research is needed to help men make an informed choice regarding screening.

59 Evaluating two decision AIDS for australian men to support informed choice about prostate cancer screening

2018 ◽  
Author(s):  
Kristen Pickles ◽  
Alex Barratt ◽  
Jolyn Hersch ◽  
Kevin McGeechan ◽  
Kirsten McCaffery
Keyword(s):  
Prostate Cancer ◽  
Cancer Screening ◽  
Prostate Cancer Screening ◽  
Decision Aids ◽  
Informed Choice

scholarly journals Men’s preferences for prostate cancer screening: a discrete choice experiment

2013 ◽  
Vol 108 (3) ◽  
pp. 533-541 ◽  
Author(s):  
E W de Bekker-Grob ◽  
J M Rose ◽  
B Donkers ◽  
M-L Essink-Bot ◽  
C H Bangma ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Screening ◽  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Choice Experiment ◽  
Prostate Cancer Screening

Patient preference for prostate-specific antigen testing: A population-based analysis.

2011 ◽  
Vol 29 (7_suppl) ◽  
pp. 188-188
Author(s):  
S. L. Chang ◽  
J. C. Presti ◽  
J. P. Richie
Keyword(s):  
Prostate Cancer ◽  
Decision Making ◽  
Cancer Screening ◽  
Patient Preferences ◽  
Prostate Cancer Screening ◽  
Population Based ◽  
Decision Making Process ◽  
Shared Decision ◽  
Psa Testing ◽  
History Of

188 Background: The AUA and American Cancer Society both recommend a shared decision-making process between clinicians and patients for prostate cancer screening with PSA testing. Data are limited data regarding patient preferences for PSA evaluation in the United States. We assessed the sociodemographic and clinical characteristics of men who proceeded with or opted out of PSA testing in a nationally representative population-based cohort. Methods: We analyzed male participants from the 2001 to 2008 cycles of the National Health and Nutrition Examination Survey (NHANES) who were 40 years old or older without a history of prostate cancer, recent prostate manipulation, or hormone therapy use (n = 6,032). All men underwent or refused PSA testing after a standardized explanation about prostate cancer screening by a physician. A multivariate logistic regression was conducted after adjusting for survey weights to identify independent sociodemographic and clinical predictors for opting out of PSA testing. Results: Overall, 5% of the study cohort refused PSA testing. The analysis revealed predictors for refusing PSA testing (Table). PSA testing preference was not influenced by a family history of prostate cancer, previous prostate cancer screening, education level, socioeconomic status, insurance status, or tobacco history. There were no significant time trends for PSA testing. Conclusions: Despite equal access to PSA testing in our study, there was unequal utilization. We found that Black men were more likely to refuse PSA testing. Our analysis also suggests that a perception of suboptimal health or uncertain future outlook may discourage men from undergoing PSA evaluation. These patient preferences for PSA evaluation should be factored into the shared decision-making process for prostate cancer screening. [Table: see text] No significant financial relationships to disclose.

scholarly journals Significance of the method of selective blood collection from the inferior petrosal sinuses for differential diagnosis of ACTH-dependent hypercorticism

2009 ◽  
Vol 55 (6) ◽  
pp. 35-40 ◽  
Author(s):  
I I Dedov ◽  
Z E Belaya ◽  
I I Sitkin ◽  
E I Marova ◽  
E G Przhiyalkovskaya ◽  
...  
Keyword(s):  
False Negative ◽  
Differential Diagnostics ◽  
Blood Collection ◽  
Advantages And Disadvantages ◽  
Negative Results ◽  
False Negative Results ◽  
History Of ◽  
Alternative Techniques ◽  
Pharmaceutical Agents ◽  
Selective Collection

This review paper was designed to discuss the accumulated worldwide experience with selective collection of blood from the inferior petrose sinuses for the purpose of differential diagnostics of ACTH-dependent hypercorticism. The history of the development of the method is described, principal indications and contraindications to its clinical application are considered with reference to the informative value of this diagnostic tool. Possible causes of false positive and false negative results as well as complications ever reported as associated with the diagnostic procedure are discussed. Much attention is given to the comparative analysis of advantages and disadvantages of alternative techniques for blood collection and to the use of pharmaceutical agents that may increase efficiency of the method under consideration.

scholarly journals Sensitivity of prostate cancer foci using 1.5 T multiparametric magnetic resonance imaging

2020 ◽  
Author(s):  
Suguru Ito ◽  
SEI NAITO ◽  
Takafumi Narisawa ◽  
Mayu Yagi ◽  
Yuta Kurota ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
False Negative ◽  
Resonance Imaging ◽  
Prostate Imaging ◽  
Multiparametric Magnetic Resonance Imaging ◽  
Negative Results ◽  
False Negative Results ◽  
Clinically Significant

Abstract Background The detection of prostate cancer (CaP) has increasingly being carried out by multiparametric magnetic resonance imaging (mpMRI). Despite many previous studies, the sensitivity for clinically significant CaP (csCaP) was high, information on mpMRI false-negative lesions is limited. Therefore, the aim of this study was to evaluate the use and limitations of mpMRI in CaP. Methods A total of 228 CaP foci in 100 patients who underwent 1.5 T mpMRI and radical prostatectomy between December 2015 and June 2017 were retrospectively analyzed. The sensitivities of CaP foci, csCaP, and index tumors (ITs) were measured. Clinically significant CaP was defined into two categories based on the Gleason score (GS): csCaP/GS ≥ 3 + 4 (GS ≥ 3 + 4 or diameter > 10 mm) and csCaP/GS ≥ 4 + 3 (GS ≥ 4 + 3 or diameter > 10 mm). In addition, the characteristics of false-negative lesions were identified. The Prostate Imaging Reporting and Data System version 2 was used to determine an mpMRI positive lesion, defined as a lesion having a score of ≥ 3. Results The sensitivity of all legions, csCaP/GS ≥ 3 + 4, csCaP/GS ≥ 4 + 3, and ITs were 61.4%, 75.8%, 83.0%, and 91%, respectively. There were 91 lesions that were mpMRI false, 40% of which were csCaP/GS ≥ 3 + 4. There were three lesions with a GS of ≥ 8 and ≥ 10 mm in the false-negative results. Conclusions mpMRI can highly detect ITs and csCaP/GS ≥ 4 + 3; however, a few large and high-GS CaPs constitute undetectable lesions in 1.5 T mpMRI.

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