scholarly journals The clinical features of posterior scleritis with serous retinal detachment: A retrospective clinical analysis

2018 ◽  
Author(s):  
Zhizhang Dong ◽  
Yifeng Gan ◽  
Yinan Zhang ◽  
Yu Zhang ◽  
Juan Li ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Clinical Features ◽  
Statistical Significance ◽  
Serous Retinal Detachment ◽  
Ultrasound Biomicroscopy ◽  
Clinical Analysis ◽  
Enhanced Depth Imaging ◽  
Blurred Vision ◽  
Posterior Scleritis ◽  
Axis Length

Abstract Objective: To summarize the clinical features, systemic associations, risk factors and choroidal thickness(CT) changing in posterior scleritis (PS) with serous retinal detachment. Methods: This retrospective study included 23 patients with PS with retinal detachment from August 2012 to July 2017. All patients were documented with the Medical history and clinical features were recorded. The examinations included best corrected visual acuity (BACV), intraocular pressure（IOP）, fundus examination, routine eye examinations. Posterior coats thickness (PCT) was determined by B scan Ultrasound, the CT was measured by enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). And clinical data were compiled and analyzed. Results: After application of extensive exclusion criteria, 23 patients with PS remained (13 females, 10 males). The average age at presentation was 29.5 ± 9.24 years old. Ocular pain and blurred vision were the two most common symptoms complained by patients. Anterior scleritis occurred in 12 patients, which was confirmed by Ultrasound Biomicroscopy (UBM) examination. Despite all patients displaying serous retinal detachment in their macula, no fluorescein leakage was observed in the macular. Optic disc swelling was documented in 10 of the 23 eyes. From B-scan ultrasound examination, the PCT increased with fluid in Tenon’s capsule demonstrated as a typical T-sign. The average PCT was 2.51 ± 0.85 mm in the PS-affected eye and only 1.09 ± 0.29 mm in the unaffected eye; this difference reached statistical significance. The subfoveal CT increased to an average of 442.61 ± 55.61μm, which correlated with axis length and PCT, but not with IOP. The BCVA and IOP did not correlate with either CT or the PCT. Conclusions: PS with serous retinal detachment presented with a variety of symptoms, such as pain and visual loss, and physical indicators. Typical T-sign detected by B-scan ultrasound was a useful confirmatory sign for PS diagnosis. Pathological increases in CT might be a potential predictive factor for inflammation.

Prevalence and causes of clinically detectable uveitic serous retinal detachment

2021 ◽  
pp. 112067212199139
Author(s):  
Robert M Kinast ◽  
Sharon D Solomon ◽  
Leo DP Cubillan ◽  
Anna Hovakimyan ◽  
Nisha Acharya ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Clinical Finding ◽  
Chart Review ◽  
Serous Retinal Detachment ◽  
Retrospective Chart Review ◽  
Intraocular Lymphoma ◽  
Posterior Scleritis ◽  
Common Cause ◽  
Toxoplasmic Retinochoroiditis ◽  
Vkh Disease

Purpose: To describe the prevalence and causes of clinically detectable uveitic serous retinal detachment (SRD). Methods: Retrospective chart review of a large clinic-based series. Results: Serous retinal detachment was present in 78 of the 2761 (2.8%) patients. Vogt-Koyanagi-Harada (VKH) disease was the most commonly identified cause (38/78, 48.7%). Less common associated etiologies included toxoplasmic retinochoroiditis (8/78, 10.3%), sarcoidosis (5/78, 6.4%), intraocular lymphoma (4/78, 5.1%), presumed tuberculosis (3/78, 3.8%), and posterior scleritis (2/78, 2.6%). Fifteen patients (19.2%) with uveitic SRD at presentation had no identifiable etiology and were labeled idiopathic or indeterminant. Thirty of the 38 patients with VKH disease (78.9%) had positive neurological and/or integumentary findings, and therefore constituted either complete or incomplete subtypes of the disease. The remaining eight (21.1%) had presumed/ocular VKH disease limited to the eye. Conclusion: While VKH disease by far is the most common cause of clinically detectable uveitic SRD, a number of other non-infectious and infectious inflammatory disorders were also associated with this distinctive clinical finding.

scholarly journals Efficacy of Aflibercept for DME with Different OCT Types

2021 ◽  
Author(s):  
Yuan Tao ◽  
Mingrong Kou ◽  
Xia Yang ◽  
Yixiao Li ◽  
Shuting Li ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Macular Edema ◽  
Intravitreal Injection ◽  
Statistical Significance ◽  
Serous Retinal Detachment ◽  
Post Treatment ◽  
Foveal Thickness ◽  
Time Points ◽  
Central Foveal Thickness

Abstract Background: This study aimed to assess efficacy differences of aflibercept by intravitreal injection for diabetic macular edema (DME) with different OCT types. Methods: according to OCT morphology, 128 patients (128 eyes) with DME were divided into the diffuse retinal thickening (DRT; 41 patients, 41 eyes), cystoid macular edema (CME; 47 patients, 47 eyes), and serous retinal detachment (SRD; 40 patients, 40eyes) groups. All patients were treated by intravitreal injection of 0.5 mg (0.05 mL) aflibercept according to the 3+prn regimen. BCVA (LogMAR) and central foveal thickness (CFT) among the three groups at baseline, and 1 month, 3 months, 6 months and 12 months after treatment, respectively, were assessed. Results: At 1 month, 3 months, 6 months and 12 months after treatment, improvements in BCVA and CFT in the three groups showed statistical significance (P<0.05). BCVA improvement was better at all time points in the DRT group compared with the SRD group (P<0.05). BCVA improvement was also better in the CME group compared with the SRD group at 6 months and 12 months post-treatment (P<0.05). At 1 month, 3 months and 6 months after treatment, CFT differences among the three groups had no statistical significance (P>0.05), while at 12 months post-treatment, CFT values among the three groups had significant differences (F=3.77, P=0.0269). at 12 months after treatment, CFT improvement was better in the DRT and CME groups compared with the SRD group (P<0.05). Conclusion: aflibercept by intravitreal injection could significantly improve visual acuity in DME patients with different OCT types and reduce CFT. At the initial treatment of 12 months, CFT and BCVA improvements in the DRT and CME types were the most pronounced.

scholarly journals Acute Posterior Multifocal Placoid Pigment Epitheliopathy Sharing Characteristic OCT Findings of Vogt-Koyanagi-Harada Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Yuta Kitamura ◽  
Toshiyuki Oshitari ◽  
Masayasu Kitahashi ◽  
Takayuki Baba ◽  
Shuichi Yamamoto
Keyword(s):  
Retinal Detachment ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Late Phase ◽  
Serous Retinal Detachment ◽  
Subretinal Fluid ◽  
Hla Typing ◽  
Blurred Vision ◽  
Fluid Analysis ◽  
Vkh Disease

A 17-year-old male presented with acute bilateral paracentral scotomata and blurred vision. Funduscopic examination showed bilateral macular serous retinal detachment and yellow-white placoid lesions at the level of retinal pigment epithelium. OCT study showed typical VKH disease findings with marked choroidal thickening and macular serous retinal detachment partly with subretinal septa in both eyes. FA demonstrated hypofluorescence at the placoid lesions in the early phase and hyperfluorescence in the late phase. Laboratory investigation showed negative result for HLA-DR4 serotype and the patient’s cerebrospinal fluid test values were within normal range. We made the diagnosis of APMPPE from these results. At 2-month follow-up without the use of corticosteroids, OCT reexamination showed complete amelioration of subretinal fluid in both eyes. Patchy pigmentary lesions also resolved clinically with partial chorioretinal scars. The results in this case suggested OCT findings in APMPPE patients could be similar to characteristic features usually found in acute VKH disease. We recommend comprehensive assessments such as FA, cerebral spinal fluid analysis, and HLA typing which help in leading proper diagnosis.

scholarly journals Choroidal Hemangioma Associated with Hepatic Hemangioma: A Case Report and Literature Review

2021 ◽  
pp. 425-432
Author(s):  
Ana Boned-Murillo ◽  
Maria Dolores Diaz-Barreda ◽  
Ana Honrubia-Grijalbo ◽  
Olivia Esteban-Floria ◽  
Francisco Javier Ascaso Puyuelo
Keyword(s):  
Case Report ◽  
Retinal Detachment ◽  
Serous Retinal Detachment ◽  
Hepatic Hemangioma ◽  
Tumor Type ◽  
Central Scotoma ◽  
Blurred Vision ◽  
Choroidal Hemangioma ◽  
Elevated Lesion ◽  
History Of

Circumscribed choroidal hemangioma (CCH) is a rare congenital ocular tumor type that is usually benign and asymptomatic. CCH has only been reported once previously in the literature in association with a visceral neoplasm. Here, we present a newly described association between CCH and hepatic hemangioma (HH). We report the case of a 57-year-old woman diagnosed with asymptomatic HHs who presented with a 2- to 3-month history of central scotoma and blurred vision in her left eye. Assessment identified an orange-red elevated lesion with a central serous retinal detachment and subretinal edema. Complementary tests suggested a CCH. To our knowledge, CCH has only been reported once previously in association with a visceral neoplasm, making this newly described association between CCH and HH of clinical relevance. Ophthalmologists should be aware of the possible association between CCH and other visceral tumors as this association offers an opportunity for the early detection of this pathology.

scholarly journals Pachychoroid Spectrum Disorder Findings in Patients with Coronavirus Disease 2019

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Mojtaba Abrishami ◽  
Ramin Daneshvar ◽  
Nasser Shoeibi ◽  
Neda Saeedian ◽  
Hamid Reza Heidarzadeh ◽  
...  
Keyword(s):  
Serous Retinal Detachment ◽  
Spectrum Disorder ◽  
Enhanced Depth Imaging ◽  
Blurred Vision ◽  
Depth Imaging ◽  
History Of ◽  
Imaging Optical Coherence Tomography ◽  
Visual Disturbances ◽  
Choroidal Hyperpermeability ◽  
Pachychoroid Pigment Epitheliopathy

Purpose. To report the occurrence of acute, bilateral, central serous chorioretinopathy (CSC), and pachychoroid spectrum disorder findings in patients with coronavirus disease 2019 (COVID-19). Methods. In recovered cases of COVID-19 with visual disturbances, complete ocular examinations with multimodal retinal and choroidal evaluation, including enhanced depth imaging optical coherence tomography, fluorescein or indocyanine green angiography, and blue autofluorescence, were obtained. Results. Four COVID-19 recovered patients presented with bilateral blurred vision. Ocular examination and imaging revealed pachychoroid and pachyvessels associated with choroidal hyperpermeability without any obvious intraocular inflammation. Bilateral localized serous retinal detachment was obvious in three cases compatible with pachychoroid associated with CSC manifestation and pachychoroid pigment epitheliopathy in one patient. CSC was resolved with treatment by steroidal antimineralocorticoid (Eplerenone) in two patients and by photodynamic therapy in one patient. None of the patients reported emotional stress and history of corticosteroid consumption. Conclusion. Hyperpermeability of the choroid, pachychoroidopathy, or choroidal vessel congestion can be observed or exacerbated in association with COVID-19.

scholarly journals Serous Retinal Detachment in Pre-eclampsia: Case Report and Literature Review

2020 ◽  
Vol 42 (11) ◽  
pp. 772-773
Author(s):  
Joana Teresa Botelho Vasconcelos Raposo ◽  
Bruna Carina Da Silva Melo ◽  
Nuno Filipe Bernardo Belo Maciel ◽  
Sara Dias Leite ◽  
Óscar Renato Coutinho Rebelo ◽  
...  
Keyword(s):  
Case Report ◽  
Retinal Detachment ◽  
Caesarean Delivery ◽  
Visual Loss ◽  
Rare Complication ◽  
Serous Retinal Detachment ◽  
Blurred Vision ◽  
Serous Macular Detachment ◽  
Choroidal Ischemia ◽  
Angiographic Findings

AbstractPre-eclampsia (PE) is an obstetric disease with a multifactorial cause that affects ∼ 5% of pregnant women. Vision can be affected with varying severity, and retinal detachment is a very rare complication. It tends to be bilateral, diagnosed postpartum, and more prevalent in women who are primiparous and/or undergo caesarean delivery. The condition typically resolves completely and rarely causes total visual loss in the affected women. Fluorescence angiographic findings support the hypothesis that retinal detachment in PE is secondary to choroidal ischemia from intense arteriolar vasospasm. The present article is related to a case of a 37-year-old pregnant woman who had PE associated with a progressive blurred vision, diagnosed by ophthalmology as serous macular detachment of the retina.

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