Development and Validation of a Psoriasis Treatment Acceptability Measure through Group Concept Mapping

Abstract Background: Psoriasis is a common autoimmune dermatologic condition which has a pronounced negative impact on patient quality of life and disease burden. Currently, there are a number of treatments available for psoriasis, with differences in efficacy, mechanism of action, mode of administration, adverse effects, and tolerability. However, a reliable, validated patient-reported instrument to address patient expectations and of psoriasis treatment has not been developed. This project was undertaken with the aim of developing a fit-for-purpose self-reported instrument to inform patient expectations and preferences of psoriasis treatments.Methods: Two studies, both utilizing qualitative and quantitative methods, were conducted in patients within the entire spectrum of psoriasis severity. In Study 1, a group concept mapping (GCM) exercise was conducted with dermatologists and moderate-to-severe psoriasis patients to identify concepts important in the treatment of psoriasis. In Study 2, a preliminary Treatment Acceptability Questionnaire (TAQ) was developed using GCM-derived concepts from Studies 1 and 2, followed by cognitive debriefing (CD) telephone interviews of the preliminary TAQ. In Study 2, another GCM exercise was conducted with mild and newly diagnosed psoriasis patients. Psychometric analyses were performed on the TAQ to evaluate validity and reliability.Results: The Study 1 GCM exercise generated 43 concepts from moderate-to-severe psoriasis patients (n=20) and dermatologists (n=10). In Study 2, 37 GCM concepts were generated from mild and newly diagnosed psoriasis patients (n=20). From the 2 GCM exercises, 28 concepts were selected to form the preliminary TAQ; CD interviews indicated strong understanding and relevance of TAQ items among patients with disease ranging from mild to severe. The final TAQ consisted of 20 items; psychometric analysis demonstrated strong validity and reliability of the TAQ. Conclusions: The TAQ is a novel psychometrically validated fit-for-purpose patient-reported instrument to inform healthcare providers of patients’ expectations of and preferences for treatment of their psoriasis and can help in shared decision making between patients and physicians.

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PRS61 USING GROUP CONCEPT MAPPING METHODOLOGY TO EXPLORE COPD PATIENT EXPERIENCE AND AID SELECTION OF PATIENT-REPORTED OUTCOME MEASURES IN COPD FOR USE IN CLINICAL TRIALS

Value in Health ◽

10.1016/j.jval.2019.04.1765 ◽

2019 ◽

Vol 22 ◽

pp. S361

Author(s):

S. Keith ◽

L. Humphrey ◽

S. Bozzi ◽

M. Reaney

Keyword(s):

Clinical Trials ◽

Concept Mapping ◽

Outcome Measures ◽

Patient Experience ◽

Patient Reported Outcome Measures ◽

Patient Reported Outcome ◽

Group Concept Mapping ◽

Patient Reported ◽

Group Concept ◽

Selection Of

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Conceptualizing researchers’ perspectives on involving professionals in research: a group concept mapping study

Health Research Policy and Systems ◽

10.1186/s12961-021-00685-2 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Christine E. Laustsen ◽

Albert Westergren ◽

Pia Petersson ◽

Maria Haak

Keyword(s):

Data Collection ◽

Concept Mapping ◽

Hierarchical Cluster ◽

Research Process ◽

Scaling Analysis ◽

Research Projects ◽

Research And Practice ◽

Group Concept Mapping ◽

Process Adaptation ◽

Group Concept

Abstract Background Researchers have shown an increased interest in involving professionals from outside academia in research projects. Professionals are often involved in research on ageing and health when the purpose is to address the gap between research and practice. However, there is a need to acquire more knowledge about what the involvement might lead to by exploring researchers’ experiences of involving professionals in research on ageing and health and developing conceptual areas. Therefore, the aim of this study was to identify conceptual areas of professionals’ involvement in research on ageing and health, from the perspective of researchers themselves. Methods Group concept mapping, a participatory and mixed method, was used to conceptualize areas. Researchers with experience of involving professionals in research projects on ageing and health participated in qualitative data collection through brainstorming sessions (n = 26), and by sorting statements (n = 27). They then took part in quantitative data collection, where they rated statements according to how much a statement strengthened research (n = 26) and strengthened practice (n = 24). Data were analysed using multidimensional scaling analysis and hierarchical cluster analysis. In addition, a qualitative analysis of the latent meaning of the cluster map was conducted. Results Analysis of the sorting stage generated five clusters illustrating conceptual areas of professionals’ involvement in research projects on ageing and health. The five clusters are as follows: complex collaboration throughout the research process; adaptation of research to different stakeholders, mutual learning through partnership; applicable and sustainable knowledge; legitimate research on ageing and health. The qualitative latent meaning of the cluster map showed two themes: the process of involvement and the outcome of involvement. A positive strong correlation (0.87) was found between the rating of strengthened research and practice. Conclusions This study reveals conceptual areas on a comprehensive and illustrative map which contributes to the understanding of professionals’ involvement in research on ageing and health. A conceptual basis for further studies is offered, where the aim is to investigate the processes and outcomes entailed in involving professionals in research on ageing and health. The study also contributes to the development of instruments and theories for optimizing the involvement of professionals in research.

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