scholarly journals The Correlation between Follow-up MRI Findings and Laboratory Results in Pyogenic Spondylodiscitis

2020 ◽  
Author(s):  
Kyung-Sik Ahn ◽  
Chang Ho Kang ◽  
Suk-Joo Hong ◽  
Baek Hyun Kim ◽  
Euddeum Shim

Abstract Background Although MRI is the gold-standard imaging method in the diagnosis of spondylodiscitis, role of follow-up imaging is debated and there can be discrepancies with regard to the significance of bony or soft tissue responses to treatment. Purpose of our study is to test whether the MRI changes on follow-up imaging correlate with laboratory findings of treatment response. Methods A total of 48 patients with pyogenic spondylodiscitis who underwent baseline and follow-up MRI were retrospectively reviewed. The extent of bone marrow edema, paravertebral soft tissue inflammation, and disc height were compared on baseline and follow-up MRIs with the C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels obtained from the medical records at baseline and on follow-up. Relationships between the MRI and laboratory changes were analyzed using the Spearmann correlation test. Results The mean MRI follow-up period was 42.25 days. Based on the CRP (resolved: n=19, resolving: n=19, and aggravated: n=10), there was significant correlation between the laboratory results and the changes in the bone and soft tissues (p < 0.01, both). The correlation was best with soft tissue changes (rho: 0.48) followed by bony changes (rho: 0.41). Based on the ESR (resolved: n=8, resolving: n=22, and worsened: n=18), the correlation was stronger with bone changes (rho: 0.45, p < 0.01) than it was with soft tissue changes (rho: 0.39, p = 0.01). Conclusion Follow-up MRI findings of pyogenic spondylodiscitis show variable tissue responses. CRP was best correlated with soft tissue changes, while ESR showed the best association with bony changes.

2020 ◽  
Author(s):  
Kyung-Sik Ahn ◽  
Chang Ho Kang ◽  
Suk-Joo Hong ◽  
Baek Hyun Kim ◽  
Euddeum Shim

Abstract Background: Although MRI is the gold-standard imaging method in the diagnosis of spondylodiscitis, role of follow-up imaging is debated and there can be discrepancies with regard to the significance of bony or soft tissue responses to treatment. Purpose of our study is to test whether the MRI changes on follow-up imaging correlate with laboratory findings of treatment response.Methods: A total of 48 patients with pyogenic spondylodiscitis who underwent baseline and follow-up MRI were retrospectively reviewed. The extent of bone marrow edema, paravertebral soft tissue inflammation, and disc height were compared on baseline and follow-up MRIs with the C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels obtained from the medical records at baseline and on follow-up. Relationships between the MRI and laboratory changes were analyzed using the Spearmann correlation test.Results: The mean MRI follow-up period was 42.25 days. Based on the CRP (resolved: n=19, resolving: n=19, and aggravated: n=10), there was significant correlation between the laboratory results and the changes in the bone and soft tissues (p < 0.01, both). The correlation was best with soft tissue changes (rho: 0.48) followed by bony changes (rho: 0.41). Based on the ESR (resolved: n=8, resolving: n=22, and worsened: n=18), the correlation was stronger with bone changes (rho: 0.45, p < 0.01) than it was with soft tissue changes (rho: 0.39, p = 0.01).Conclusion: Follow-up MRI findings of pyogenic spondylodiscitis show variable tissue responses. CRP was best correlated with soft tissue changes, while ESR showed the best association with bony changes.


2020 ◽  
Author(s):  
Kyung-Sik Ahn ◽  
Chang Ho Kang ◽  
Suk-Joo Hong ◽  
Baek Hyun Kim ◽  
Euddeum Shim

Abstract Background Although MRI is the gold-standard imaging method in the diagnosis of spondylodiscitis, role of follow-up imaging is debated and there can be discrepancies with regard to the significance of bony or soft tissue responses to treatment. Purpose of our study is to test whether the MRI changes on follow-up imaging correlate with laboratory findings of treatment response. Methods A total of 48 patients with pyogenic spondylodiscitis who underwent baseline and follow-up MRI were retrospectively reviewed. The extent of bone marrow edema, paravertebral soft tissue inflammation, and disc height were compared on baseline and follow-up MRIs with the C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels obtained from the medical records at baseline and on follow-up. Relationships between the MRI and laboratory changes were analyzed using the Spearmann correlation test. Results The mean MRI follow-up period was 42.25 days. Based on the CRP (resolved: n=19, resolving: n=19, and aggravated: n=10), there was significant correlation between the laboratory results and the changes in the bone and soft tissues (p < 0.01, both). The correlation was best with soft tissue changes (rho: 0.48) followed by bony changes (rho: 0.41). Based on the ESR (resolved: n=8, resolving: n=22, and worsened: n=18), the correlation was stronger with bone changes (rho: 0.45, p < 0.01) than it was with soft tissue changes (rho: 0.39, p = 0.01). Conclusion Follow-up MRI findings of pyogenic spondylodiscitis show variable tissue responses. CRP was best correlated with soft tissue changes, while ESR showed the best association with bony changes.


2020 ◽  
Author(s):  
Kyung-Sik Ahn ◽  
Chang Ho Kang ◽  
Suk-Joo Hong ◽  
Baek Hyun Kim ◽  
Euddeum Shim

Abstract Background Although MRI is the gold-standard imaging method in the diagnosis of spondylodiscitis, role of follow-up imaging is debated and there can be discrepancies with regard to the significance of bony or soft tissue responses to treatment. Purpose of our study is to test whether the MRI changes on follow-up imaging correlate with laboratory findings of treatment response. Methods A total of 48 patients with pyogenic spondylodiscitis who underwent baseline and follow-up MRI were retrospectively reviewed. The extent of bone marrow edema, paravertebral soft tissue inflammation, and disc height were compared on baseline and follow-up MRIs with the C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels obtained from the medical records at baseline and on follow-up. Relationships between the MRI and laboratory changes were analyzed using the Spearmann correlation test. Results The mean MRI follow-up period was 42.25 days. Based on the CRP (resolved: n=19, resolving: n=19, and aggravated: n=10), there was significant correlation between the laboratory results and the changes in the bone and soft tissues (p < 0.01, both). The correlation was best with soft tissue changes (rho: 0.48) followed by bony changes (rho: 0.41). Based on the ESR (resolved: n=8, resolving: n=22, and worsened: n=18), the correlation was stronger with bone changes (rho: 0.45, p < 0.01) than it was with soft tissue changes (rho: 0.39, p = 0.01). Conclusion Follow-up MRI findings of pyogenic spondylodiscitis show variable tissue responses. CRP was best correlated with soft tissue changes, while ESR showed the best association with bony changes.


2018 ◽  
Vol 12 (1) ◽  
pp. 366-376
Author(s):  
Rahul Tiwari ◽  
P. Srinivas Chakravarthi ◽  
Vivekanand S. Kattimani ◽  
Krishna Prasad Lingamaneni

Background: Facial appearance is an important factor, affects social and psychological well-being. The ideal positioning of jaws and soft tissues is crucial during orthognathic surgery for a better outcome, but the response of facial soft tissues does not always reflect the exact movements of the underlying jaws in 1:1 ratio. So, soft tissue changes following orthognathic surgery require utmost attention during surgical correction to make successful treatment. Aims and Objectives: Evaluation of perioral soft tissue changes after orthognathic surgical procedures. The objectives of the study were to assess and compare pre and post-operative perioral soft tissue changes of lip width, nasolabial and mentolabial angle using Three Dimensional Computed Tomography scan (3DCT). Patient and Methods: The study involved ten patients for evaluation requiring orthognathic surgical procedures (maxillary or mandibular anteroposterior excess or deficiency, transverse deformities, vertical maxillary excess and facial asymmetry) presented to the department of oral and maxillofacial surgery during 2014-2016. Pre and post-operative 3DCT scan were taken after 12 months using iCT 256 slice whole body CT scanner and evaluated for changes using Dicom PMS D view. Results: Significant changes were observed in nasolabial angle after maxillary advancement (1.81°) and maxillary setback procedure (2.73°). The mentolabial angle was significantly increased with mandibular setback procedures (3.27°). Mandibular advancement procedures showed both increase (3.6°) and decrease (7.6°) in mentolabial angle. Conclusion: 3DCT showed a significant difference in perioral soft tissue changes in nasolabial and mentolabial angle but no significant change was observed in lip width. 3DCT is a reliable tool for 3D assessment. The conventional thought of changes in Nasolabial angle after surgery is changing due to the underlying factors which should be considered for prediction.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Kyung-Sik Ahn ◽  
Chang Ho Kang ◽  
Suk-Joo Hong ◽  
Baek Hyun Kim ◽  
Euddeum Shim

2020 ◽  
Author(s):  
Hieu Nguyen ◽  
Jeong Won Shin ◽  
Hai-Van Giap ◽  
Ki Beom Kim ◽  
Hwa Sung Chae ◽  
...  

Abstract Background The aim of this study was to assess the mid-facial soft tissue changes induced by a micro-implant-supported maxillary skeletal expander in late adolescents and young adults by cone-beam computerized tomography and the correlations between hard and soft tissue changes after expansion with maxillary skeletal expander.Subjects and methods Twenty patients with maxillary transverse deficiency treated with maxillary skeletal expander were selected. Cone-beam computerized tomography images taken before and after expansion were superimposed to measure the changes in soft and hard tissue landmarks.Results Anterior nasal spine, posterior nasal spine, and alveolar bone width were significantly increased after expansion with maxillary skeletal expander (p < 0.05). The average lateral movement of the cheek points was 1.13 ± 0.33 mm (left) and 1.41 ± 0.39 mm (right), while that of the alar curvature points was 1.07 ± 0.72 mm (left) and 1.06 ± 0.68 (right) (p < 0.05). The average forward displacement of the cheek points was 0.42 ± 0.66 mm (left) and 0.60 ± 0.58 mm (right), whereas that of the alar curvature points was 0.80 ± 0.67 mm (left) and 0.68 ± 0.56 mm (right) side (p < 0.05). The average downward movement of the subnasale was 0.40 ± 0.37 mm (p < 0.05). The changes in cheek points and alar curvature points on both sides significantly correlated with hard-tissue changes (p < 0.05).Conclusions Maxillary expansion using maxillary skeletal expander resulted in significant lateral and forward movement of soft tissues of the cheek and alar curvature points on both sides and correlated with the maxillary suture opening at the anterior and posterior nasal spines.


2018 ◽  
Vol 4 (4) ◽  
pp. 1245-1250 ◽  
Author(s):  
Ahmed AL-Omar ◽  
Usama AL-Dakroroy

The objective of this study was to evaluate the soft tissue changes after anterior maxillary osteotomy using cone beam computed tomography. The study included twelve patients diagnosed as suffering from an excess of the anterior part of maxilla and required surgical correction by anterior maxillary osteotomy. Assessment of Cone beam computed tomography in evaluation the soft tissue changes. All cases subjected to anterior maxillary osteotomy using modified Cuper technique. Follow up of cases was does clinically and radio- graphically by cone beam computed tomography. The results of the study proved that the statistically significant increase in mean Nasolabial angle after 6 months was 5.2 degrees, the mean value of nasal width after 6 months was 0,9mm. The mean value of Philtrum length was 3.3mm. In conclusion, Cone Beam Computed Tomography can be used to obtain dimensionally accurate linear and angular measurement from bony maxillofacial structure and landmarks and allows accurate, three-dimensional imaging of hard and soft tissues.


2017 ◽  
Vol 88 (9) ◽  
pp. 876-886 ◽  
Author(s):  
Bassam M. Kinaia ◽  
Filip Ambrosio ◽  
Monica Lamble ◽  
Kristyn Hope ◽  
Maanas Shah ◽  
...  

2021 ◽  
Author(s):  
Xun Xia ◽  
Zhen-Yu Wei ◽  
Jiang-Qin Huang ◽  
Chang-Qi Hu ◽  
Shui-Gen Guo ◽  
...  

Abstract BackgroundThis study aims to evaluate the clinical outcomes of a new implant restoration strategy for patients with limited interocclusal space in the posterior region.Materials and MethodsA total of 37 patients (19 females and 18 males) were enrolled in this study and received 62 implants. A locking taper implant (Bicon) was used for the first stage procedure, which was placed >2mm under the bone. An extraoral cementation technique was used to cement the crown and abutment. The survival and success rate of the implant restorations were evaluated using the plaque index, modified bleeding index, probing depth, marginal bone loss, and the patient's subjective satisfaction. ResultsThe soft tissues around the implant were healthy and did not show any indications of peri-implantitis. The success rate of the new implant restorations was >96% at the 1-year follow-up. The patients presented satisfactory outcomes at the 1-year follow-up. The marginal bone loss and soft tissue changes were not significantly different at different depths of placement (p>0.05).ConclusionsAccording to the results, the use of a locking taper implant and adoption of appropriate prosthetic strategies might be an effective procedure for the prosthetic rehabilitation of patients with limited interocclusal space and reduced occlusal vertical dimensions.


2014 ◽  
Vol 85 (4) ◽  
pp. 631-637 ◽  
Author(s):  
Halise Aydemir ◽  
Ruchengiz Efendiyeva ◽  
Hakan Karasu ◽  
Ufuk Toygar-Memikoğlu

ABSTRACT Objective:  To assess soft tissues in the short and long term after bimaxillary surgery in Class III patients by comparing the hard tissue changes and results between time periods. Materials and Methods:  Twenty-six Class III adult patients treated with bimaxillary surgery were included in the study. Cephalometric records were taken before surgery (T1) and 5 months (T2), 1.4 years (T3), 3 years (T4), and 5 years (T5) after surgery. Results:  There was no significant relapse in skeletal parameters. Overjet was significantly reduced between T4-T3 time intervals (P &lt; .01). There were significant increases in Sn-HR, ULA-HR, LLA-HR, B-B∧ (P &lt; .01), and B∧-HR (P &lt; .05) between T4-T3 time intervals. There was no significant change in the soft tissue parameters between T5-T4 time intervals. Conclusion:  Soft tissue vertical relapse occurs in skeletally stabile Class III bimaxillary surgery patients in the first 3 years after surgery.


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