scholarly journals Carbon nanoparticles for identification of metastatic lymph nodes around the superior mesenteric artery in transverse colon cancer

2020 ◽  
Author(s):  
YuXin Xu ◽  
Pan Chi ◽  
Ying Huang ◽  
XiaoJie Wang ◽  
DaoXiong Ye
Keyword(s):  
Colon Cancer ◽  
Lymph Nodes ◽  
Superior Mesenteric Artery ◽  
Transverse Colon ◽  
Mesenteric Artery ◽  
Carbon Nanoparticles ◽  
Transverse Colon Cancer ◽  
Carbon Nanoparticle ◽  
Metastatic Lymph Nodes ◽  
Positive Station

Abstract Background Accurate identification of metastatic lymph nodes around the superior mesenteric artery (SMA), with or without metastasis, is vital for surgeons when dissecting lymph nodes in patients with transverse colon cancer. In the current study, we evaluated the prospect of using carbon nanoparticles in identification of lymph nodes around SMA. Methods We recruited a total of 220 patients, with transverse colon cancer, and divided them into two groups. The first group (n=51) was carbon nanoparticle (CN) while the other (n=169) had no carbon nanoparticle (NCN) group. Intraoperative and post-operative data were compared between the groups. Results We found that 117 patients were negative for D1 lymph nodes, while 3.4% were positive for D2 lymph nodes. Additionally, 169 patients were negative for D2 lymph nodes while 10.7% of patients were positive for D3 lymph nodes. Laparoscopy easily identified black-dyed lymph nodes in the CN group. Significantly higher numbers of positive station D3 lymph nodes (0.63 ± 2.43 vs 0.29 ± 1.03, p = 0.006), number of positive station 214 nodes (0.10 ± 0.13 vs 0.08 ± 0.17, p = 0.004), the number of positive lymph nodes (2.69 ± 5.38 vs 1.90 ± 4.22, p = 0.037), and the number of total lymph nodes (39.67 ± 19.33 vs 34.50 ± 18.99, p = 0.037) were found in the CN compared to NCN group. However, we found no significant differences between CN and NCN groups with regards to the number of positive station D1 and D2 lymph nodes. Conclusions We successfully identified metastases 214 LNs around SMA in transverse colon cancer using carbon nanoparticles. These particles have potential to significantly increase the number of positive and negative lymph nodes.

scholarly journals The feasibility and safety of complete laparoscopic extended right hemicolectomy with preserving the ileocecal junction in right-transverse colon cancer

2020 ◽  
Author(s):  
Hao Su ◽  
Hongliang Wu ◽  
Bing Mu ◽  
Mandula Bao ◽  
Shou Luo ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Nodes ◽  
Transverse Colon ◽  
Operation Time ◽  
Right Hemicolectomy ◽  
Control Group ◽  
Transverse Colon Cancer ◽  
Metastatic Lymph Nodes ◽  
Ileocecal Junction ◽  
Metastatic Lymph

Abstract Background: To evaluate the feasibility and safety of a new surgical method, complete laparoscopic extended right hemicolectomy with preserving the ileocecal junction in right-transverse colon cancer.Methods: We retrospectively analyzed and compared the data of consecutive patients with right-transverse colon cancer who underwent complete laparoscopic extended right hemicolectomy with preserving the ileocecal junction (n=23) and conventional complete laparoscopic extended right hemicolectomy (n=34) in our hospital between October 2017 to May 2019, respectively.Results: The overall operation time of the ileocecal junction-preserved group was significantly shorter than that of the control group (p=0.024). There was no difference in the number of harvested lymph nodes, metastatic lymph nodes and rate of metastatic lymph nodes (p＞0.05). The ileocecal junction-preserved group showed shorter time of first flatus, lower frequency of postoperative diarrhea and shorter duration of postoperative hospitalization. Furthermore, it also showed that the defecation frequency was lower in the ileocecal junction-preserved group than control group on the 1st, 3rd and 6th month (p＜0.05), and the number of patients who defecated at night or defecated four times or more a day were less in the ileocecal junction-preserved group than control group on the 1st month (p＜0.05).Conclusion: The complete laparoscopic extended right hemicolectomy with preserving the ileocecal junction promises as a safe and feasible surgical procedure for right-transverse colon cancer, associated with earlier recovery of bowel function, shorter operation time and similar pathological outcomes when compared to the conventional laparoscopic procedure.

scholarly journals Személyre szabott kezelés szinkrón, nyirokcsomó-pozitív petefészek- és vastagbéldaganatban

2015 ◽  
Vol 156 (23) ◽  
pp. 939-943 ◽  
Author(s):  
Dániel Deme ◽  
Abdulfatah M. Bishr ◽  
Jamool Nizar ◽  
András Telekes
Keyword(s):  
Ovarian Cancer ◽  
Colon Cancer ◽  
Lymph Nodes ◽  
Transverse Colon ◽  
Combined Treatment ◽  
Colonic Neoplasms ◽  
Tubular Adenocarcinoma ◽  
Transverse Colon Cancer ◽  
Regional Lymph Nodes ◽  
Lower Quadrant

A 71-year-old female patient underwent urgent laparotomy due to severe right lower quadrant abdominal pain and fever. Macroscopically duplex coecal and transverse colon cancer as well as a sigmoid or left ovarian cancer were suspected. Pathological findings revealed synchronous left ovarian and transverse colonic neoplasms. Both primaries metastatized to their regional lymph nodes. Furthermore, the ovarian cancer infiltrating the sigmoid colon gave distant metastasis in the coecum, too. Ovarian cancer histology showed papillary adenocarcinoma, and transverse colon cancer was a tubular adenocarcinoma. The affected lymph nodes were clearly distinguished by immunohistochemistry staining: ovarian metastases were CK7 positive, and colonic metastases were CK20 and CEA positive. The patient was treated with combinated chemotherapy: FOLFOX-4 two weekly and paclitaxel monotherapy every other week. The patient tolerated this combined treatment well. The authors conclude that multiple synchronous neoplasms can be treated with individualized chemotherapeutic protocol with good efficacy and few adverse reactions. Orv. Hetil., 2015, 156(23), 939–943.

scholarly journals A case of portal venous gas after obstructive transverse colon cancer surgery

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Yuichiro Furutani ◽  
Chikashi Hiranuma ◽  
Masakazu Hattori ◽  
Kenji Doden ◽  
Yasuo Hashizume
Keyword(s):  
Colon Cancer ◽  
Conservative Treatment ◽  
Anastomotic Leakage ◽  
Transverse Colon ◽  
Cancer Surgery ◽  
Transverse Colon Cancer ◽  
Bowel Necrosis ◽  
Entire Area ◽  
Portal Venous Gas ◽  
Colon Cancer Surgery

Abstract Background Portal venous gas has traditionally been considered an inevitable harbinger of death due to its association with bowel necrosis. Recently, an increasing number of cases of portal venous gas have been reported in patients with various clinical conditions and without bowel necrosis. We herein report the case of a patient in whom portal venous gas developed after transverse colon cancer surgery. Case presentation A 69-year-old man who had transverse colon cancer underwent insertion of a transanal ileus tube for decompression. Transverse colon resection was performed on the 11th day after the insertion of the transanal ileus tube. The patient had a high fever on the 6th day after the operation. Computed tomography showed portal venous gas over the entire area of the liver and pneumatosis intestinalis in the wall of the ascending colon. There were no signs of anastomotic leakage or bowel necrosis, so we decided to use conservative therapy with fasting and antibiotics. The portal venous gas disappeared on the 19th day after the operation. The patient was discharged in good condition on the 29th day after the operation. Conclusions Conservative treatment for portal venous gas is reasonable for patients without signs of anastomotic leakage or bowel necrosis. However, it is important to carefully observe patients with portal venous gas during conservative treatment because portal venous gas may be life-threatening.

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