The feasibility and safety of complete laparoscopic extended right hemicolectomy with preserving the ileocecal junction in right-transverse colon cancer

Abstract Background: To evaluate the feasibility and safety of a new surgical method, complete laparoscopic extended right hemicolectomy with preserving the ileocecal junction in right-transverse colon cancer.Methods: We retrospectively analyzed and compared the data of consecutive patients with right-transverse colon cancer who underwent complete laparoscopic extended right hemicolectomy with preserving the ileocecal junction (n=23) and conventional complete laparoscopic extended right hemicolectomy (n=34) in our hospital between October 2017 to May 2019, respectively.Results: The overall operation time of the ileocecal junction-preserved group was significantly shorter than that of the control group (p=0.024). There was no difference in the number of harvested lymph nodes, metastatic lymph nodes and rate of metastatic lymph nodes (p＞0.05). The ileocecal junction-preserved group showed shorter time of first flatus, lower frequency of postoperative diarrhea and shorter duration of postoperative hospitalization. Furthermore, it also showed that the defecation frequency was lower in the ileocecal junction-preserved group than control group on the 1st, 3rd and 6th month (p＜0.05), and the number of patients who defecated at night or defecated four times or more a day were less in the ileocecal junction-preserved group than control group on the 1st month (p＜0.05).Conclusion: The complete laparoscopic extended right hemicolectomy with preserving the ileocecal junction promises as a safe and feasible surgical procedure for right-transverse colon cancer, associated with earlier recovery of bowel function, shorter operation time and similar pathological outcomes when compared to the conventional laparoscopic procedure.

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Carbon nanoparticles for identification of metastatic lymph nodes around the superior mesenteric artery in transverse colon cancer

10.21203/rs.3.rs-19228/v1 ◽

2020 ◽

Author(s):

YuXin Xu ◽

Pan Chi ◽

Ying Huang ◽

XiaoJie Wang ◽

DaoXiong Ye

Keyword(s):

Colon Cancer ◽

Lymph Nodes ◽

Superior Mesenteric Artery ◽

Transverse Colon ◽

Mesenteric Artery ◽

Carbon Nanoparticles ◽

Transverse Colon Cancer ◽

Carbon Nanoparticle ◽

Metastatic Lymph Nodes ◽

Positive Station

Abstract Background Accurate identification of metastatic lymph nodes around the superior mesenteric artery (SMA), with or without metastasis, is vital for surgeons when dissecting lymph nodes in patients with transverse colon cancer. In the current study, we evaluated the prospect of using carbon nanoparticles in identification of lymph nodes around SMA. Methods We recruited a total of 220 patients, with transverse colon cancer, and divided them into two groups. The first group (n=51) was carbon nanoparticle (CN) while the other (n=169) had no carbon nanoparticle (NCN) group. Intraoperative and post-operative data were compared between the groups. Results We found that 117 patients were negative for D1 lymph nodes, while 3.4% were positive for D2 lymph nodes. Additionally, 169 patients were negative for D2 lymph nodes while 10.7% of patients were positive for D3 lymph nodes. Laparoscopy easily identified black-dyed lymph nodes in the CN group. Significantly higher numbers of positive station D3 lymph nodes (0.63 ± 2.43 vs 0.29 ± 1.03, p = 0.006), number of positive station 214 nodes (0.10 ± 0.13 vs 0.08 ± 0.17, p = 0.004), the number of positive lymph nodes (2.69 ± 5.38 vs 1.90 ± 4.22, p = 0.037), and the number of total lymph nodes (39.67 ± 19.33 vs 34.50 ± 18.99, p = 0.037) were found in the CN compared to NCN group. However, we found no significant differences between CN and NCN groups with regards to the number of positive station D1 and D2 lymph nodes. Conclusions We successfully identified metastases 214 LNs around SMA in transverse colon cancer using carbon nanoparticles. These particles have potential to significantly increase the number of positive and negative lymph nodes.

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The feasibility and safety of complete laparoscopic extended right hemicolectomy with preservation of the ileocecal junction in right-transverse colon cancer

World Journal of Surgical Oncology ◽

10.1186/s12957-020-01922-8 ◽

2020 ◽

Vol 18 (1) ◽

Author(s):

Hao Su ◽

Hongliang Wu ◽

Bing Mu ◽

Mandula Bao ◽

Shou Luo ◽

...

Keyword(s):

Colon Cancer ◽

Transverse Colon ◽

Right Hemicolectomy ◽

Transverse Colon Cancer ◽

Ileocecal Junction

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A Case Report of Recurrent Transverse Colon Cancer, which was Metastasized to the Gastric Regional Lymph Nodes 6 Years Later from Right Hemicolectomy

The Japanese Journal of Gastroenterological Surgery ◽

10.5833/jjgs.37.223 ◽

2004 ◽

Vol 37 (2) ◽

pp. 223-228 ◽

Cited By ~ 1

Author(s):

Hisashi Amaike ◽

Hiroki Taniguchi ◽

Nobuaki Fuji ◽

Katsuhiko Oka ◽

Kazuki Inaba ◽

...

Keyword(s):

Colon Cancer ◽

Case Report ◽

Lymph Nodes ◽

Transverse Colon ◽

Right Hemicolectomy ◽

Transverse Colon Cancer ◽

Regional Lymph Nodes

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Lymph node retrieval after resection of rectal cancer following preoperative chemoradiotherapy

Medicina ◽

10.3390/medicina46050042 ◽

2010 ◽

Vol 46 (5) ◽

pp. 299 ◽

Cited By ~ 5

Author(s):

Tadas Latkauskas ◽

Paulius Lizdenis ◽

Rasa Jančiauskienė ◽

Darius Pranys ◽

Algimantas Tamelis ◽

...

Keyword(s):

Rectal Cancer ◽

Lymph Nodes ◽

Advanced Rectal Cancer ◽

Control Group ◽

Study Group ◽

Preoperative Radiochemotherapy ◽

Metastatic Lymph Nodes ◽

Tumor Bearing ◽

Metastatic Lymph ◽

The Mean

Background. According to the current guidelines of proper TNM staging, 12 lymph nodes per specimen are crucial. This study assessed the role of preoperative radiochemotherapy on the number of lymph nodes detected in the tumor-bearing specimen. Material and methods. Retrospective data of 138 patients who underwent surgery for stage II and III rectal cancer without preoperative radiochemotherapy during the period of 2004–2006 (control group) were compared with prospective data of 38 patients who received preoperative radiochemotherapy during the period of 2007–2008 (study group). The number of patients with metastatic lymph nodes, number of lymph nodes per specimen, number of metastatic lymph nodes per specimen, and the size of the tumor between the groups were compared. Results. Positive lymph nodes were detected in 88 (64%) patients in the control group as compared with 9 (21%) patients in the study group (P<0.05). The mean number of lymph nodes per specimen in the control group was 13.5, while in the study group, the mean number of lymph nodes per specimen was 6.29 (P<0.05). There was a significant difference in the mean number of metastatic lymph nodes per specimen between the groups (5.12 in the control group versus 2.11 in the study group; P<0.05). The mean size of the tumor was 4.37 cm in the control group and 2.45 cm in the study group (P<0.01). Conclusions. Preoperative radiochemotherapy for advanced rectal cancer significantly decreased the number of lymph nodes detected in the tumor-bearing specimen. This also resulted in a significant decrease in the number of metastatic lymph nodes detected in the specimen, and fewer patients with stage III (N+) cancer were diagnosed. Preoperative radiochemotherapy could induce a significant downsizing and downstaging of advanced rectal cancer, but great care in operative and pathologic examination techniques must be taken to ensure appropriate staging.

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Application of nano-carbon and titanium clip combined labeling in robot-assisted laparoscopic transverse colon cancer surgery

10.21203/rs.3.rs-40555/v2 ◽

2020 ◽

Author(s):

Nan Lin ◽

Jiandong Qiu ◽

Junchuan Song ◽

Changwei Yu ◽

Yongchao Fang ◽

...

Keyword(s):

Colon Cancer ◽

Transverse Colon ◽

Operation Time ◽

Cancer Surgery ◽

Colon Tumor ◽

Transverse Colon Cancer ◽

Robot Assisted ◽

Plain Films ◽

Colon Cancer Surgery ◽

Nano Carbon

Abstract Background: Robot-assisted laparoscopic transverse colon tumor surgery requires precise tumor localization. The purpose of this study was to evaluate the safety and efficacy of nano-carbon and titanium clip combination labeling methods in robot-assisted transverse colon tumor surgery.Methods: From January 2018 to January 2019, the clinical data of 16 patients who underwent preoperative nano-carbon and titanium clip combined with robot-assisted laparoscopic transverse colon cancer surgery were retrospectively analyzed.Results: Of the 16 patients, no signs of abdominal pain, fever, or diarrhea were observed after colonoscopy. Two titanium clips were seen on all of the 16 patients' abdominal plain films. Nano-carbon staining sites were observed during the operation, and no staining disappeared or abdominal cavity contamination. All patients underwent R0 resection. The average number of lymph nodes harvsted was 18.23±5.04 (range, 9-32). The average time to locate the lesion under the laparoscopic was 3.03±1.26 min(range, 1-6min), and the average operation time was 321.43±49.23 min (range, 240-400min). All were consistent with the surgical plan, and there was no intraoperative change of surgical procedure or conversion to open surgery.Conclusion: Preoperative colonoscopy combined with nano-carbon and titanium clip is safe and effective in robot-assisted transverse colon cancer surgery. A At the same time, the labeling method shows potential in shortening the operation time, ensuring sufficient safety margin and reducing complications.

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