scholarly journals Short-Term Changes in the Anterior Segment and Retina after Small Incision Lenticule Extraction

2020 ◽  
Author(s):  
Yanwei Chen ◽  
Huaping Liao ◽  
Yue Sun ◽  
Xi Shen
Keyword(s):  
Layer Thickness ◽  
Optic Disc ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Vessel Density ◽  
Small Incision Lenticule Extraction ◽  
Short Term ◽  
Small Incision ◽  
Lenticule Extraction

Abstract Background: To analyse short-term changes in the anterior segment and retina after small incision lenticule extraction (SMILE).Methods: Patients with myopia scheduled for SMILE were recruited from Ruijin Hospital, Shanghai, China. Basic patient information such as age, sex, and refractive errors was recorded. Ocular measurements were taken before surgery, and 1 day and 1 week after surgery; they included axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), pupil diameter (PD), macular thickness (MT), ganglion cell layer thickness (GCL), retinal nerve fiber layer thickness (RNFL), choroidal thickness (CT), macular vessel density, and optic disc vessel density.Results: Sixty-one eyes of 31 patients were selected for this study. AL, CCT, ACD, and postoperative PD were significantly reduced (p<0.05), while LT was thickened after surgery (p<0.05). MT at the fovea decreased 1 day and 1 week after surgery (p<0.05). GCL showed no significant changes after surgery. RNFL was unchanged 1 day after surgery, but the inferior sector was thickened 1 week after surgery. CT was thicker at the fovea 1 day after surgery and 1.0 mm from the fovea in the nasal sector 1 week after surgery. Macular vessel density was significantly decreased 1 day after surgery and most recovered in 1 week. Optic disc vessel density decreased at the peripapillary part 1 day after surgery and recovered after 1 week. 𝜟ACD and 𝜟LT showed no significant correlation 1 day after surgery. 𝜟ACD was negatively correlated with 𝜟LT and sphere 1 week after surgery (r=-0.847, p<0.000; r=-0.398, p=0.002). 𝜟LT was positively correlated with the sphere 1 week after surgery (r=0.256, p=0.048).Conclusion: The anterior segment was the most affected, while the retina also underwent changes with regard to MT, RNFL, CT, macular vessel density, and peripapillary vessel density.

scholarly journals Short-term changes in the anterior segment and retina after small incision lenticule extraction

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yanwei Chen ◽  
Huaping Liao ◽  
Yue Sun ◽  
Xi Shen
Keyword(s):  
Layer Thickness ◽  
Optic Disc ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Vessel Density ◽  
Small Incision Lenticule Extraction ◽  
Short Term ◽  
Small Incision ◽  
Lenticule Extraction

Abstract Background To analyse short-term changes in the anterior segment and retina after small incision lenticule extraction (SMILE). Methods Patients with myopia scheduled for SMILE were recruited from Ruijin Hospital, Shanghai, China. Basic patient information such as age, sex, and refractive errors was recorded. Ocular measurements were taken before surgery, and 1 day and 1 week after surgery; they included axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), pupil diameter (PD), macular thickness (MT), ganglion cell layer thickness (GCL), retinal nerve fiber layer thickness (RNFL), choroidal thickness (CT), macular vessel density, and optic disc vessel density. Results Sixty-one eyes of 31 patients were selected for this study. AL, CCT, ACD, and postoperative PD were significantly reduced (p < 0.05), while LT was thickened after surgery (p < 0.05). MT at the fovea decreased 1 day and 1 week after surgery (p < 0.05). GCL showed no significant changes after surgery. RNFL was unchanged 1 day after surgery, but the inferior sector was thickened 1 week after surgery. CT was thicker at the fovea 1 day after surgery and 1.0 mm from the fovea in the nasal sector 1 week after surgery. Macular vessel density was significantly decreased 1 day after surgery and most recovered in 1 week. Optic disc vessel density decreased at the peripapillary part 1 day after surgery and recovered after 1 week. ΔACD and ΔLT showed no significant correlation 1 day after surgery. ΔACD was negatively correlated with ΔLT and sphere 1 week after surgery (r = − 0.847, p < 0.000; r = − 0.398, p = 0.002). ΔLT was positively correlated with the sphere 1 week after surgery (r = 0.256, p = 0.048). Conclusion The anterior segment was the most affected, while the retina also underwent changes with regard to MT, RNFL, CT, macular vessel density, and peripapillary vessel density.

scholarly journals Short-Term Changes in the Anterior Segment and Retina after Small Incision Lenticule Extraction

2020 ◽  
Author(s):  
Yanwei Chen ◽  
Huaping Liao ◽  
Yue Sun ◽  
Xi Shen
Keyword(s):  
Layer Thickness ◽  
Optic Disc ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Vessel Density ◽  
Small Incision Lenticule Extraction ◽  
Short Term ◽  
Small Incision ◽  
Lenticule Extraction

Abstract Background: To analyse short-term changes in the anterior segment and retina after small incision lenticule extraction (SMILE). Methods: Patients with myopia scheduled for SMILE were recruited from Ruijin Hospital, Shanghai, China. Basic patient information such as age, sex, and refractive errors was recorded. Ocular measurements were taken before surgery, and 1 day and 1 week after surgery; they included axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), pupil diameter (PD), macular thickness (MT), ganglion cell layer thickness (GCL), retinal nerve fiber layer thickness (RNFL), choroidal thickness (CT), macular vessel density, and optic disc vessel density. Results: Sixty-one eyes of 31 patients were selected for this study. AL, CCT, ACD, and postoperative PD were significantly reduced (p<0.05), while LT was thickened after surgery (p<0.05). MT at the fovea decreased 1 day and 1 week after surgery (p<0.05). GCL showed no significant changes after surgery. RNFL was unchanged 1 day after surgery, but the inferior sector was thickened 1 week after surgery. CT was thicker at the fovea 1 day after surgery and 1.0 mm from the fovea in the nasal sector 1 week after surgery. Macular vessel density was significantly decreased 1 day after surgery and most recovered in 1 week. Optic disc vessel density decreased at the peripapillary part 1 day after surgery and recovered after 1 week. 𝜟ACD and 𝜟LT showed no significant correlation 1 day after surgery. 𝜟ACD was negatively correlated with 𝜟LT and sphere 1 week after surgery (r=-0.847, p<0.000; r=-0.398, p=0.002). 𝜟LT was positively correlated with the sphere 1 week after surgery (r=0.256, p=0.048). Conclusion: The anterior segment was the most affected, while the retina also underwent changes with regard to MT, RNFL, CT, macular vessel density, and peripapillary vessel density.

scholarly journals Short Term Changes in Anterior Segment and Retina After Small Incision Lenticule Extraction

2020 ◽  
Author(s):  
Yanwei Chen ◽  
Huaping Liao ◽  
Yue Sun ◽  
Xi Shen
Keyword(s):  
Layer Thickness ◽  
Optic Disc ◽  
Pearson Correlation ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Vessel Density ◽  
Small Incision Lenticule Extraction ◽  
Short Term ◽  
Small Incision ◽  
Lenticule Extraction

Abstract Purpose: To analyze changes of the anterior segment and retina after small incision lenticule extraction (SMILE) in the short term.Methods: Myopia patients scheduled for SMILE were recruited in Ruijin Hospital, Shanghai, China. Basic information of patients such as age, gender, and refractive errors was recorded. Ocular measurements were taken before surgery, 1 day and 1 week after surgery, including axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), white to white (WTW), pupil diameter (PD), macular thickness (MT), ganglion cell layer thickness (GCL), retinal nerve fiber layer thickness (RNFL), choroidal thickness (CT), macular vessel density, optic disc vessel density. Results of postoperative were compared to baseline, respectively, with paired student t test, and the results were considered statistically significant when p<0.05. Correlations between sphere and changes of ACD (𝜟ACD) and LT (𝜟LT) were analyzed with the Pearson correlation coefficient.Results: 61 eyes of 31 patients were selected for this study. AL, CCT, ACD, and PD postoperative were significantly reduced (p<0.05), while LT was thickened after surgery (p<0.05). MT at the fovea decreased on 1 day and 1 week after surgery (p<0.05). GCL was no statistical changes after surgery. RNFL was unchanged 1 day after surgery, but the inferior sector was thickened 1 week after surgery. CT was observed thicker at fovea 1 day after surgery and 1.0mm from the fovea in nasal 1 week after surgery. Macular vessel density was significantly decreased on 1 day after surgery and most recovered in 1 week. Optic disc vessel density decreased at the peripapillary part on 1 day after surgery and recovered in 1 week. 𝜟ACD and 𝜟LT were found no significant correlation on 1 day after surgery. 𝜟ACD was negatively correlated with 𝜟LT and sphere on 1 week after surgery (r=-0.847, p<0.000; r=-0.398, p=0.002). 𝜟LT was positively correlated with the sphere on 1 week after surgery (r=0.256, p=0.048).Conclusion: Anterior segment was the most influenced while the retina was also impacted in MT, RNFL, CT, macular vessel density, and peripapillary vessel density.

scholarly journals Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Yu-Chi Liu ◽  
Lasitha Jayasinghe ◽  
Heng Pei Ang ◽  
Nyein Chan Lwin ◽  
Gary Hin Fai Yam ◽  
...  
Keyword(s):  
Corneal Thickness ◽  
Anterior Segment ◽  
Histological Section ◽  
The Other ◽  
Lamellar Thickness ◽  
Small Incision Lenticule Extraction ◽  
Small Incision ◽  
Lenticule Extraction

This study aimed at evaluating the effect of intraoperative corneal pocket irrigation in small incision lenticule extraction (SMILE) and compares it to that in femtosecond laser-assisted in situ keratomileusis (FS-LASIK). Sixteen rabbit eyes underwent a SMILE procedure, with 8 eyes having corneal pocket irrigation, while the other 8 eyes were without irrigation. Another 16 eyes underwent a FS-LASIK procedure for comparison, with 8 eyes having flap irrigation, while the other 8 eyes were without irrigation. The results showed that the changes in the total corneal thickness, anterior and posterior lamellar thickness, measured by the anterior segment optical coherence tomography, were comparable between the SMILE with and without irrigation groups, suggesting that the irrigation did not lead to significant changes in the corneal thickness. However, at postoperative 8 hours, in vivo confocal microscopy showed that the interface reflectivity in the SMILE with irrigation group was significantly higher than that in other three groups. The presence of interface fluid was further confirmed by the identification of fluid pockets with undulated collagen shown on histological section in the post-SMILE with irrigation eyes. Our findings might contribute to the occurrence of post-SMILE delayed immediate visual quality recovery and further clinical study is required.

Evolution of corneal thickness and optical density after laser in situ keratomileusis versus small incision lenticule extraction for myopia correction

2020 ◽  
pp. bjophthalmol-2020-316601
Author(s):  
Jorge Luis Alio del Barrio ◽  
Alberto Parafita-Fernandez ◽  
Mario Canto-Cerdan ◽  
Jorge L Alio ◽  
Miguel Teus
Keyword(s):  
Optical Density ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Early Postoperative Period ◽  
Laser In Situ Keratomileusis ◽  
Small Incision Lenticule Extraction ◽  
Small Incision ◽  
Lenticule Extraction ◽  
Imagej Software

PurposeTo compare the thickness and stromal optical density (OD) evolution of the flap and cap after femtosecond (FS-LASIK; Visumax) and small incision lenticule extraction (SMILE), respectively, for myopia correction.MethodsA prospective study comprising 78 eyes (n=39 per group) was performed. Anterior segment optical coherence tomography (MS39) images were collected at each postoperative visit (1 day, 1 week and 1 and 3 months) and flap/cap thicknesses were measured. Using ImageJ software, three regions were defined to measure OD (in grayscale units: flap/cap stroma, residual stromal bed (RSB) and all stroma (including flap/cap-stroma, surgical interface and RSB).ResultsMean central thickness significantly increased during the 3-month follow-up in both LASIK (5.43±4.23 μm; p=0.0118) and SMILE (2.76±5.61 μm; p=0.0118), with differences between both techniques statistically significant (p=0.020). All OD values showed a statistically significant reduction during SMILE follow-up: cap 48.96±5.55 versus 44.95±5.41 (p=0.19×10−6), RSB 50.26±7.06 versus 45.42±7.53 (p=0.00005), total stroma 50.34±6.49 versus 45.46±6.96 (p=0.5×10−5) at 1 day and 3 months, respectively, whereas no statistically significant changes were found during LASIK follow-up. No significant differences were observed in OD values between both techniques at any time point, although SMILE showed a tendency for higher OD values than LASIK within the first postoperative month. Visumax presented a tendency for thicker caps than target (11.48±7.85 μm), but not for flaps (2.73±8.93 μm) (p=0.00003).ConclusionsBoth LASIK flaps and SMILE caps show a significant postoperative rethickening. SMILE corneas present higher optical densities than LASIK corneas in the early postoperative period, with a significant decrease thereafter and up to 3 months. These findings correlate with the delayed visual recovery observed after SMILE.

scholarly journals Intraocular pressure changes and corneal biomechanics after hyperopic small-incision lenticule extraction

2019 ◽  
Author(s):  
Dan Fu ◽  
Meiyan Li ◽  
Michael C. Knorz ◽  
Shengsheng Wei ◽  
Jianmin Shang ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Mixed Model ◽  
Linear Mixed Model ◽  
Corneal Thickness ◽  
Corneal Biomechanics ◽  
Ocular Response Analyzer ◽  
Small Incision Lenticule Extraction ◽  
Corvis St ◽  
Small Incision ◽  
Lenticule Extraction

Abstract Background: To compare intraocular pressure (IOP) measurements by a dynamic Scheimpflug analyzer (Corvis ST), a non-contact tonometer, and the ocular response analyzer following hyperopic small-incision lenticule extraction (SMILE).Methods: Thirteen patients underwent hyperopic SMILE in one eye each were prospectively enrolled. IOP and corneal biomechanical parameters were measured preoperatively and 1 week, 1 month, and 3 months after surgery with a non-contact tonometer (IOPNCT), Corvis ST (biomechanical corrected IOP, bIOP), and the ocular response analyzer (Goldmann-correlated intraocular pressure [IOPg], cornea compensated IOP [IOPcc]). A linear mixed model was used to compare IOP and biomechanical values among the methods at each time point.Results: IOPNCT, IOPg, and IOPcc dropped significantly after surgery, with the amplitude being 3.15±0.48 mmHg, 5.49±0.94 mmHg, and 4.34±0.97 mmHg, respectively, at the last visit. IOPNCT decreased by 0.11±0.06 mmHg per µm of removed central corneal thickness. bIOP did not change significantly after surgery. Before surgery, no difference was found among the measurements (P> 0.05). After surgery, IOPNCT and bIOP were higher than IOPg and IOPcc. bIOP is independent of cornea thickness at the last visit, while correlated significantly with corneal biomechanics as other three IOP values did.Conclusion: bIOP (biomechanical corrected IOP as measured with the Corvis ST) seems to be an accurate parameter to measure IOP after hyperopic SMILE.

scholarly journals Small Incision Lenticule Extraction for Correction of Myopia and Myopic Astigmatism: First 24-Hour Outcomes

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Taixiang Liu ◽  
Tingting Dan ◽  
Yan Luo
Keyword(s):  
Corneal Thickness ◽  
Extraction Procedure ◽  
Corneal Edema ◽  
Pain Level ◽  
Small Incision Lenticule Extraction ◽  
Small Incision ◽  
Corneal Densitometry ◽  
Uncorrected Visual Acuity ◽  
Lenticule Extraction ◽  
Myopic Astigmatism

Purpose. To observe the first 24-hour (h) outcomes of the small incision lenticule extraction procedure (SMILE) for myopia and myopic astigmatism.Methods. Fifty-three eyes (27 patients) scheduled for SMILE were followed immediately (0 h), 2, 4, 6, and 24 h after SMILE. Uncorrected visual acuity (UCVA), conjunctival congestion, pain level, and corneal edema, thickness, and densitometry were recorded.Results. At 2 h after SMILE, 15.1% of eyes had ≤0.1 LogMAR UCVA; this increased to 62.3%, 98.1%, and 100% at 4, 6, and 24 h, respectively. Some eyes (33.96%) had mild corneal edema immediately after surgery. No 6 h postoperative edema was observed. In the first 24 h after SMILE, corneal thickness gradually decreased. Postoperative corneal densitometry values were significantly higher than preoperative values but gradually decreased during the first postoperative 24 h.Conclusions. In the first postoperative 24 h, UCVA and corneal status (edema and densitometry) improved quickly.

scholarly journals Changes in Retinal Vasculature and Thickness after Small Incision Lenticule Extraction with Optical Coherence Tomography Angiography

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Minjie Chen ◽  
Jinhui Dai ◽  
Lan Gong
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Optic Nerve ◽  
Optical Coherence Tomography Angiography ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Small Incision Lenticule Extraction ◽  
Small Incision ◽  
Lenticule Extraction ◽  
Retinal Vessel Density

Purpose. To evaluate the changes in retinal vessel density and thickness after small incision lenticule extraction (SMILE) with optical coherence tomography angiography (OCTA) in myopic patients. Methods. In this prospective study, SMILE surgeries were done in 46 eyes of 24 patients with spherical equivalent (SE) more than −6.0 diopters (D). Retinal vessel density and thickness at the macula and optic nerve were recorded with OCTA before and 1 day, 2 weeks, and 1 month after surgery. Intraocular pressure (IOP), uncorrected distance visual acuity (UDVA), and refraction were taken at the same time. Results. The superficial retinal vessel density and deep foveal retinal vessel density 1 day after surgery were less than those before surgery; however, the changes at any timepoints were not statistically significant (p=0.2736 and p=0.1590, respectively). Both the superficial vessel density and deep vessel density at the parafoveal and perifoveal regions decreased significantly 1 day postoperatively (all p<0.05) and then returned to the preoperative level at 2 weeks and stabilized thereafter. There were no significant changes in any of the 4 vessel densities in the area of peripapillary before and 1 day, 2 weeks, and 1 month after surgery (p=0.3345). No statistically significant differences between preoperative and postoperative retinal thickness were detected for the area of macula and optic nerve (all p>0.5). Conclusions. The vessel density at the parafoveal and perifoveal regions decreased at 1 day after SMILE with no effect on the visual acuity and relieved within 2 weeks. Decreased ocular blood flow in response to the spike in IOP may account for such changes.

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