Clinical analysis and predictive factors associated with improved visual acuity of infectious endophthalmitis

Abstract Background: To describe the clinical characteristics and analyze the predictive factors associated with improved visual acuity of 359 patients with infectious endophthalmitis. Methods: This study retrospectively analyzed 359 eyes of 359 patients with infectious endophthalmitis from January 2014 to December 2018. The findings summarized some epidemiological characteristics of these patients, including age, sex, occupation, patient visit time, etiology, causative organisms, therapy and best-corrected visual acuity (BCVA). Multivariate logistic regression was performed to predict the relative factors of improved visual acuity (VA). Results: Overall, 283(78.83%) patients were male.The mean age was 48.0 ± 18.27 years. Ocular truma, especially the open globe injuries (246, 68.5%) was the most common etiology of infectious endophthalmitis in this study. The etiologies of infectious endophthalmitis were open globe injuries (68.5%), intraocular surgery (22.6%), cornea ulcer-associated causes (6.7%), and endogenous causes (2.2%). In the etiology classification and visual acuity improvement group, the statistically significant difference in factors such as age, sex, patient visit time, pre-therapy VA,etc. The average Logarithm of the Minimum Angle of Resolution (logMAR) BCVA on pre-therapy was 2.28 ± 0.60, and it had significantly improved to 1.67 ± 0.83 on post-therapy (P<0.05). Logistic regression analysis showed that visit time>7 day (P=0.034, OR=0.522, 95%CI: 0.286-0.953),pre-therapy VA≦logMAR 2.3(P=0.032 ,OR=1.809, 95%CI：1.052-3.110 ), etiology of PS (vs. PT; P=0.023, OR=2.100, 95%CI:1.109-3.974) and etiology of CA(vs. PT; P=0.005, OR=0.202, 95%CI:0.066-0.621) were significantly associated with improved VA after adjusting for possible confounding factors. Conclusion: Among the patients with infectious endophthalmitis, middle-aged males, especially farmers and workers, accounted for a large proportion. Open globe injuries was the main cause and gram-positive bacteria was the major causative organisms. The final visual outcomes seem to vary according to the type of endophthalmitis, but early treatment and good initial visual acuity are important factors for visual acuity improvement.

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Brief communication (Original). Visual outcome in open globe injuries in Thailand: a prospective study

Asian Biomedicine ◽

10.5372/1905-7415.0504.070 ◽

2011 ◽

Vol 5 (4) ◽

pp. 531-536

Author(s):

Sunisa Sintuwong ◽

Ruthairat Winitchai

Keyword(s):

Visual Acuity ◽

Length Of Stay ◽

Predictive Factors ◽

Foreign Bodies ◽

Visual Outcome ◽

Time Duration ◽

Poor Visual Outcome ◽

Initial Visual Acuity ◽

Open Globe ◽

Open Globe Injuries

AbstractBackground: Eye injuries, especially open globe injuries, cause visual morbidities and socioeconomic burden. It is urgent have good database and stakeholder involvement for open globe injuries.Objectives: Investigate the epidemiology and predictive factors of visual outcome in open globe injuries in an industrial area in Thailand.Methods: Consecutive cases of in-patient open globe injuries in Mettapracharak Eye Centre between February 2009 and January 2010 were examined. Patients were interviewed at first visit and followed-up for six months. The Birmingham Eye Trauma Terminology was used to classify types of injuries. Demographic data, cost of treatment, length of stay, and predictive factors (initial visual acuity, presence of relative afferent pupillary defect, hyphema, vitreous hemorrhage, intraocular foreign bodies, retinal detachment, time-duration to surgery, and wound length) were assessed.Results: Fifty-two out of 60 eyes were included. Most (82.7%) of patients were men and average age was 34.1 years (range: 8-68 years). About half (51.9%) graduated from primary school and 65.3% were labourers. Most patients had not used protective devices. The endophthalmitis rate was 13.5%, and panophthalmitis rate was 5.8%. The enucleation rate was 9.6%. The median length of stay was nine days. Poor initial visual acuity and intraocular foreign bodies were significant predictive factors of poor visual outcome (p <0.05).Conclusion: Open globe injuries caused visual morbidity especially in young adult male, laborers with low education. Initial visual acuity and intraocular foreign bodies were significant predictive factors of poor visual outcome.

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Clinical analysis and predictive factors associated with improved visual acuity of infectious endophthalmitis

BMC Ophthalmology ◽

10.1186/s12886-020-01517-7 ◽

2020 ◽

Vol 20 (1) ◽

Cited By ~ 1

Author(s):

Zhao Gao ◽

Yunda Zhang ◽

Xiaohong Gao ◽

Ximei Zhang ◽

Tao Ma ◽

...

Keyword(s):

Visual Acuity ◽

Predictive Factors ◽

Clinical Analysis ◽

Factors Associated ◽

Infectious Endophthalmitis

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Predictive factors of visual outcome in open globe injuries in Thailand: a prospective study

Asian Biomedicine ◽

10.5372/1905-7415.0502.040 ◽

2011 ◽

Vol 5 (2) ◽

pp. 289-294

Author(s):

Sunisa Sintuwong ◽

Ruthairat Winitchai

Keyword(s):

Visual Acuity ◽

Length Of Stay ◽

Predictive Factors ◽

Foreign Bodies ◽

Vitreous Hemorrhage ◽

Visual Outcome ◽

Time Duration ◽

Initial Visual Acuity ◽

Open Globe ◽

Open Globe Injuries

AbstractBackground: Eye injuries, especially open globe injuries, cause visual morbidities and socioeconomic burden. It is an urgent task to require good database and stakeholder involvement for open globe injuries.Objectives: Investigate the epidemiology and predictive factors of visual outcome in open globe injuries in an industrial area in Thailand.Methods: Consecutive cases of in-patient open globe injuries in Mettapracharak Eye Centre between February 2009 and January 2010 were examined. Patients were interviewed at first visit and followed-up for six months. The Birmingham Eye Trauma Terminology was used to classify types of injuries. Demographic data, cost of treatment, length of stay, and predictive factors (initial visual acuity, presence of relative afferent pupillary defect, hyphema, vitreous hemorrhage, intraocular foreign bodies, retinal detachment, time-duration to surgery, and wound length) were assessed.Results: Fifty-two out of 60 eyes were included. Most (82.7%) of patients were men and average age was 34.1 years (range: 8-68 years). About half (51.9%) were graduated from primary school and 65.3% were laborers. Most patients had not used protective devices. The endophthalmitis rate was 13.5%, and panophthalmitis rate was 5.8%. The enucleation rate was 9.6%. The median length of stay was nine days. Poor initial visual acuity and intraocular foreign bodies were significant predictive factors (p <0.05).Conclusion: Open globe injuries caused visual morbidity especially in young adult male, laborers with low education. Initial visual acuity and intraocular foreign bodies were significant predictive factors.

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Open-globe injuries in Palestine: epidemiology and factors associated with profound visual loss at St. John Eye Hospital, Jerusalem Riyad Banayot St. John Eye Hospital, Jerusalem, Palestine

Ophthalmology Journal ◽

10.5603/oj.2021.0031 ◽

2021 ◽

Vol 6 (0) ◽

pp. 165-170

Author(s):

Riyad Banayot

Keyword(s):

Visual Loss ◽

Factors Associated ◽

Open Globe ◽

Open Globe Injuries

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Ectopic eruption of the maxillary second molar: Predictive factors

The Angle Orthodontist ◽

10.2319/020917-95 ◽

2017 ◽

Vol 87 (4) ◽

pp. 583-589 ◽

Cited By ~ 1

Author(s):

Soonshin Hwang ◽

Yoon Jeong Choi ◽

Ji Yeon Lee ◽

Chooryung Chung ◽

Kyung-Ho Kim

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Logistic Regression Analysis ◽

Predictive Factors ◽

Multivariate Logistic Regression Analysis ◽

Key Factors ◽

Multivariate Logistic Regression ◽

Factors Associated ◽

Ectopic Eruption ◽

Maxillary Tuberosity

ABSTRACT Objective: The purpose of this study was to investigate the diagnostic aspects, contributing conditions, and predictive key factors associated with ectopic eruption of maxillary second molars. Material and Methods: This retrospective study evaluated the study models, lateral cephalographs, and panoramic radiographs of 40 adult subjects (20 men, 20 women) with bilateral ectopic eruption and 40 subjects (20 men, 20 women) with normal eruption of the maxillary second molars. Studied variables were analyzed statistically by independent t-tests, univariate and multivariate logistic regression analysis, followed by receiver-operating characteristic analysis. Results: Tooth widths of bilateral lateral incisors, canines, and premolars were wider in the ectopic group, which resulted in greater arch lengths. The ANB angle and maxillary tuberosity distance (PTV-M1, PTV-M2) were smaller in the ectopic group. The long axes of the maxillary molars showed significant distal inclination in the ectopic group. The multivariate logistic regression analysis showed that three key factors—arch length, ANB angle, and PTV-M1 distance—were significantly associated with ectopic eruption of the second molars. The area under the curve (AUC) was the largest for the combination of the three key factors with an AUC greater than 0.75. PTV-M1 alone was the single factor that showed the strongest association with ectopic eruption (AUC = 0.7363). Conclusions: An increase in arch length, decrease in ANB angle, and decrease in maxillary tuberosity distance to the distal aspect of the maxillary first molar (PTV-M1) were the most predictive factors associated with ectopic eruption of maxillary second molars.

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25-Gauge Vitrectomy in Open Eye Injury with Retained Foreign Body

Journal of Ophthalmology ◽

10.1155/2017/3161680 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

G. Sborgia ◽

N. Recchimurzo ◽

A. Niro ◽

L. Sborgia ◽

A. Sborgia ◽

...

Keyword(s):

Visual Acuity ◽

Foreign Body ◽

Clinical Status ◽

Case Series ◽

Eye Injury ◽

Retained Foreign Body ◽

Open Globe ◽

Open Globe Injuries ◽

25 Gauge Vitrectomy

Purpose. Ocular trauma with retained foreign body is an important cause of visual impairment in working-age population. Clinical status impacts on the timing and planning of surgery. In the last year small gauge vitrectomy has become safer and more efficient, extending the range of pathologies successfully treated.Aims. To evaluate the safety and outcomes in patients with open eye injury with retained foreign body that underwent early 25-gauge vitrectomy.Methods. In this retrospective, noncomparative, interventional case series, we performed 25-gauge vitrectomy on 10 patients affected by open globe injuries with retained foreign body, over 3 years. We analyzed age, wound site, foreign body characteristics, ocular lesions correlated, relative afferent pupillary defect, visual acuity, and intraocular pressure. Follow-up evaluations were performed at 1, 3, and 6 months. According to the clinical status we performed other procedures to manage ocular correlated lesions.Results. The median age of patients was 37 years. The foreign body median size was 3.5 mm (size range, 1 to 10 mm). 25-gauge vitrectomy was performed within 12 hours of trauma. Foreign body removal occurred via a clear corneal or scleral tunnel incision or linear pars plana scleral access. Visual acuity improved in all patients. Endophthalmitis was never reported. Only two cases reported postoperative ocular hypertension resolved within the follow-up. Retinal detachment recurred in one case only.Conclusions. 25-gauge vitrectomy could be considered as early approach to manage open globe injuries with a retained posterior segment foreign body in selected cases with good outcomes and low complication rate.

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Prognostic Factors and Epidemiology of Open Globe Injuries from Western Sydney: A Twelve-Year Review

10.21203/rs.3.rs-294147/v1 ◽

2021 ◽

Author(s):

Haochi Ho ◽

Jane Foo ◽

Yi-Chiao Li ◽

Samantha Bobba ◽

Christopher Go ◽

...

Keyword(s):

Visual Acuity ◽

Prognostic Factors ◽

Retinal Detachment ◽

Case Series ◽

Final Visual Acuity ◽

Ocular Injury ◽

Visual Outcomes ◽

Globe Rupture ◽

Open Globe ◽

Open Globe Injuries

Abstract BackgroundTo identify prognostic factors determining final visual outcome following open globe injuries.MethodsRetrospective case series of patients presenting to Westmead Hospital, Sydney, Australia with open globe injuries from 1st January 2005 to 31st December 2017. Data collected included demographic information, ocular injury details, management and initial and final visual acuities.ResultsA total of 104 cases were identified. Predictors of poor final visual outcomes included poor presenting visual acuity (p < 0.001), globe rupture (p < 0.001), retinal detachment (p < 0.001), Zone III wounds (p < 0.001), hyphema (p=0.003), lens expulsion (p = 0.003) and vitreous hemorrhage (p < 0.001). Multivariate analysis demonstrated presenting visual acuity (p < 0.001), globe rupture (p = 0.013) and retinal detachment (p = 0.011) as being statistically significant for predicting poor visual outcomes. The presence of lid laceration (p = 0.197) and uveal prolapse (p = 0.667) were not significantly associated with the final visual acuity. ConclusionsPoor presenting visual acuity, globe rupture and retinal detachment are the most important prognostic factors determining final visual acuity following open globe injury.

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An Important Cause of Blindness in Children: Open Globe Injuries

Journal of Ophthalmology ◽

10.1155/2016/7173515 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 5

Author(s):

Meral Yildiz ◽

Sertaç Argun Kıvanç ◽

Berna Akova-Budak ◽

Ahmet Tuncer Ozmen ◽

Sadık Gorkem Çevik

Keyword(s):

Visual Acuity ◽

Retinal Detachment ◽

Visual Impairment ◽

Primary Repair ◽

Final Visual Acuity ◽

Who Criteria ◽

Open Globe ◽

The Mean ◽

And Gender ◽

Open Globe Injuries

Objective. Our aim was to present and evaluate the predictive factors of visual impairment and blindness according to WHO criteria in pediatric open globe injuries.Methods. The medical records of 94 patients younger than 18 years who underwent primary repair surgery were reviewed retrospectively. The initial and final visual acuity, anterior and posterior segment findings, and zone of injury were noted. The patients were classified as blindness in one eye or visual impairment in one eye.Results. Of 412 patients who presented with open globe injury, 94 (23%) were under 18 years old. Fifty-four (16 females, 38 males) children were included. The mean age of the children was 7.1 ± 4.1 years. According to WHO criteria, 19 of 54 patients (35%) had unilateral blindness and 8 had unilateral visual impairment (15%). There was no significant relationship between final visual acuity and gender and injured eye. In visually impaired and blind patients, presence of preoperative hyphema, retinal detachment, and zone 2 and zone 3 injuries was significantly higher.Conclusion. Presence of hyphema and zone 2 and zone 3 injuries and retinal detachment may end up with visual impairment and/or blindness in children.

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