scholarly journals Missing during COVID-19 lockdown: children with new-onset type 1 diabetes

Author(s):  
Devi Dayal ◽  
Saniya Gupta ◽  
Dhvani Raithatha ◽  
Muralidharan Jayashree

Abstract The redistribution of healthcare resources for coronavirus 2019 (COVID-19) pandemic has resulted in unintentional neglect of essential non-COVID-19 care (1). In low- and lower-middle income countries (LMIC), the already overstretched healthcare systems have crumbled under the COVID-19 pressure (2). Additionally, hardline lockdown restrictions, and fear of exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in healthcare settings have forced patients with non-COVID-19 illnesses to stay home and suffer until their illness deteriorates substantially, and sometimes irreversibly. The impact of COVID-19 on the pediatric population has so far been mild, except in children with comorbidities (3). However, children who develop new time-sensitive non-COVID-19 illnesses during the pandemic are at risk of worsening or death due to compromised access to hospital care. In particular, children with new-onset type 1 diabetes (T1D) may progress rapidly to diabetic ketoacidosis (DKA) if treatment with insulin is delayed, and are therefore at risk of increased morbidity and mortality.

2020 ◽  
Vol 211 ◽  
pp. 108319 ◽  
Author(s):  
Andrea Vecchione ◽  
Roberta Di Fonte ◽  
Jolanda Gerosa ◽  
Tatiana Jofra ◽  
Maria Pia Cicalese ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 16-OR
Author(s):  
METTE DUE-CHRISTENSEN ◽  
LENE E. JOENSEN ◽  
SOPHIE SARRE ◽  
JULIE L. WAD ◽  
EWA ROMANCZUK ◽  
...  

Author(s):  
Yuichi Nishioka ◽  
Tatsuya Noda ◽  
Sadanori Okada ◽  
Tomoya Myojin ◽  
Shinichiro Kubo ◽  
...  

Diabetologia ◽  
2021 ◽  
Author(s):  
David Beran ◽  
Maria Lazo-Porras ◽  
Camille M. Mba ◽  
Jean Claude Mbanya

AbstractThe discovery of insulin in 1921 changed the prognosis for people with type 1 diabetes. A century later, availability and affordability of insulin remain a challenge in many parts of the globe. Using the WHO’s framework on understanding the life cycle of medicines, this review details the global and national challenges that affect patients’ abilities to access and afford insulin. Current research and development in diabetes has seen some innovations, but none of these have truly been game-changing. Currently, three multinational companies control over 95% of global insulin supply. The inclusion of insulin on the WHO’s Prequalification Programme is an opportunity to facilitate entry of new companies into the market. Many governments lack policies on the selection, procurement, supply, pricing and reimbursement of insulin. Moreover, mark-ups in the supply chain also affect the final price to the consumer. Whilst expenses related to diabetes are mostly covered by insurance in high-income countries, many patients from low- and middle-income countries have to pay out of their own pockets. The organisation of diabetes management within the healthcare system also affects patient access to insulin. The challenges affecting access to insulin are complex and require a wide range of solutions. Given that 2021 marks the centenary of the discovery of insulin, there is need for global advocacy to ensure that the benefits of insulin and innovations in diabetes care reach all individuals living with diabetes. Graphical abstract


2021 ◽  
Vol 9 (5) ◽  
Author(s):  
William E. Novotny ◽  
Irma Fiordalisi ◽  
Cynthia P. Keel ◽  
Glenn D. Harris

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