Synovial Sarcoma of the Cervical Spine: Case Report

Abstract PurposeTo describe a very rare case of Synovial Sarcoma affecting cervical spine vertebra.SS is a rare malignant and aggressive soft tissue tumour arising from mesenchymal cells. Primary bone origin SS is a much rarer entity that affects more commonly long bones. Ideal therapeutic strategy is yet to be defined due to very small number of cases reported so far.Case reportA 55-year-old male, construction worker, with no other relevant medical history presented with a progressive tetraparesis after recurring several times during a 4-week period to assistant physician and emergency department complaining about bilateral shoulder pain. Image studies revealed an osteolytic lesion centred on C4 vertebra with intracanalar and intraforaminal extension, causing neurologic compression. Patient was submitted to urgent surgical decompression intervention. C3 and C4 corpectomy and excisional biopsy followed by stabilization with C2-C5 arthrodesis.OutcomesNeurological deficits did not improve after surgery. Histopathological and immunohistochemical analysis revealed phenotypical characteristics of a biphasic Synovial Sarcoma. Patient died 4 weeks after surgery due to a respiratory tract infection.DiscussionSS is a malignant rare and aggressive soft tissue tumour that usually affects young adults. Very few cases of primary bone SS affecting the spine are described in literature. Imaging studies may suggest the diagnosis of synovial sarcoma but definitive diagnosis can only be confirmed by histological and immunohistochemical analysis.The rarity of these lesions demands high clinical suspicion for the diagnosis and due to the low number of cases reported ideal therapeutic strategy is yet to be defined.

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Scar sarcoidosis on a finger mimicking a rapidly growing soft tissue tumour: a case report

BMC Research Notes ◽

10.1186/1756-0500-5-2101791285670486 ◽

2012 ◽

Vol 5 (1) ◽

pp. 2101791285670486

Author(s):

Marcel-Philipp Henrichs ◽

Arne Streitbürger ◽

Georg Gosheger ◽

Carsten Surke ◽

Christian Dierkes ◽

...

Keyword(s):

Case Report ◽

Soft Tissue ◽

Soft Tissue Tumour ◽

Tissue Tumour ◽

Scar Sarcoidosis

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Cutaneous Rhinosporidiosis mimicking soft tissue tumour: A Case report with review of literature

Annals of Pathology and Laboratory Medicine ◽

10.21276/apalm.1187 ◽

2017 ◽

Vol 4 (4) ◽

pp. C102-C105 ◽

Cited By ~ 1

Author(s):

Richa Bhartiya ◽

Pallavi Agrawal ◽

Rakesh Mehra

Keyword(s):

Case Report ◽

Soft Tissue ◽

Soft Tissue Tumour ◽

Review Of Literature ◽

Tissue Tumour

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NODULAR FASCIITIS OF THE THUMB: A CASE REPORT

Hand Surgery ◽

10.1142/s0218810404001966 ◽

2004 ◽

Vol 09 (01) ◽

pp. 117-120 ◽

Cited By ~ 7

Author(s):

Roop Singh ◽

Ashwini K. Sharma ◽

Rajeev Sen

Keyword(s):

Case Report ◽

Soft Tissue ◽

Soft Tissue Tumour ◽

Nodular Fasciitis ◽

Clinicopathologic Features ◽

Tissue Tumour

Nodular fasciitis is an uncommon, benign, reactive fibroblastic soft tissue tumour. It is infrequently seen in the hand. A case of nodular fasciitis involving the thumb of a 34-year-old male is reviewed, and its clinicopathologic features are presented. Main significance lies in clinical and pathological recognition of the lesion to avoid over-treatment.

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Tophaceous Pseudogout in the Knee Joint Mimicking a Soft-Tissue Tumour: A Case Report

Journal of Orthopaedic Surgery ◽

10.1177/230949901001800127 ◽

2010 ◽

Vol 18 (1) ◽

pp. 118-121 ◽

Cited By ~ 8

Author(s):

Hiroaki Kato ◽

Kazuto Nishimoto ◽

Tomoaki Yoshikawa ◽

Katsuyuki Kusuzaki ◽

Akihiro Sudo

Keyword(s):

Case Report ◽

Soft Tissue ◽

Knee Joint ◽

Soft Tissue Tumour ◽

Tissue Tumour ◽

Tophaceous Pseudogout

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P135 Undifferentiated round cell and spindle cell sarcomas: the current paradigm

BJS Open ◽

10.1093/bjsopen/zrab032.134 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

Author(s):

Lotte Hardman ◽

Mina Ibriham ◽

Roba Khundkar ◽

Paul Wilson ◽

Lotte Hardman

Keyword(s):

Soft Tissue ◽

Spindle Cell ◽

Recent Literature ◽

Bone Neoplasms ◽

Surgical Excision ◽

Soft Tissue Tumour ◽

Round Cell ◽

Tissue Tumour ◽

Primary Bone

Abstract Introduction The classification of soft tissue and bone neoplasms is experiencing a transformation as methods to detect gene fusions expand. Next-generation sequencing panels, anchored multiplex polymerase chain reaction systems and comprehensive RNA sequencing have all contributed to new histological categorisation. The EWSR1-NFATC2 is one such novel translocation found in a round cell sarcomas. These sarcoma sit within the WHO group of undifferentiated round and spindle cell sarcomas. They presents as either a primary bone or soft tissue tumour and exhibits distinctive histopathologic features. Methods This is a case study of a soft tissue mesenchymal tumour with the recently described gene fusion EWSR1-NFATC2. The case is described, with 3-month outcomes and considered in the most recent literature on this sarcoma subset (26 cases). Results This case study prompted a look at the current NHS paradigm for these emerging histopathologically distinctive sarcoma subgroups. At present the expertise with the sarcoma MDT, along with second opinion from other national MDTs is the format for subtype specific sarcoma management, informed by recent literature. Conclusion The EWSR1-NFATC2 fusion round cell sarcoma tumours are an example of a very recently emerged sarcoma subset which display oncological variance to the wider Ewing’s family. The novel literature guided the Southmead and Royal Marsden MDT opinions to proceed straight to surgical excision. The Authors recommend a national prospective database for rare sarcoma subsets, particularly those that appear to exhibit distinctive clinicopathology characteristics. The format could be through the RSTN collaborative, secure anonymised data collection can be collected through REDCap.

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A Case Report on Angiomyxoma

Faridpur Medical College Journal ◽

10.3329/fmcj.v8i2.20396 ◽

2014 ◽

Vol 8 (2) ◽

pp. 99-101

Author(s):

Farhana Binte Monayem ◽

Zebunnessa Parvin ◽

Reaz Mahmud ◽

SK Abdul Momen Ahmed

Keyword(s):

Case Report ◽

Soft Tissue ◽

Vaginal Wall ◽

Soft Tissue Tumour ◽

Aggressive Angiomyxoma ◽

Solid Mass ◽

Adult Females ◽

Tissue Tumour ◽

Cervical Polyp

Aggressive Angiomyxoma (AA) is a rare variety of soft tissue tumour of pelvis and perineum occurring almost exclusively in adult females. AA is most often found in or in proximity to the lower pelvis, more specifically perineum, vulva, vagina or inguinal regions. Here we report a case of angiomyxoma. She is a 40 years old house wife, presented with a brownish, soft, multilocular, pedunculated nontender solid mass in the left side of the vaginal wall. Though initially it was provisionally diagnosed as a case of cervical polyp, ultimately histopathology proved it to be a case of Aggressive Angiomyxoma. DOI: http://dx.doi.org/10.3329/fmcj.v8i2.20396 Faridpur Med. Coll. J. 2013;8(2): 99-101

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Myopericytoma of the external auditory canal and tragus

The Journal of Laryngology & Otology ◽

10.1017/s0022215113001357 ◽

2013 ◽

Vol 127 (8) ◽

pp. 805-808 ◽

Cited By ~ 5

Author(s):

N A Chotey ◽

T K Naidu ◽

V Naidoo ◽

J Naidoo

Keyword(s):

Case Report ◽

Soft Tissue ◽

External Auditory Canal ◽

Clinicopathological Features ◽

Soft Tissue Tumour ◽

Anatomical Distribution ◽

Myoid Cell ◽

Spindle Cells ◽

Tissue Tumour ◽

Slow Growing

AbstractBackground:Myopericytoma is a relatively recently described skin and soft tissue tumour that demonstrates perivascular myoid cell or pericytic differentiation. Whilst the range of anatomical locations has expanded to include visceral locations, head and neck myopericytomas are rarely documented. There have been no previous reports of aural myopericytoma.Case report:This paper reports the clinicopathological features of a biopsy-proven, slow-growing, 20 × 20 mm, polypoid myopericytoma that involved the external auditory canal and tragus in an 18-year-old woman. Excision was curative.Conclusion:Heightened clinicopathological awareness of the expanding anatomical distribution of myopericytoma is critical to its diagnosis when it presents in unusual and novel locations. Myopericytoma should be added to the range of external auditory canal neoplasms, especially those characterised by an admixture of spindle cells and a prominence of blood vessels, including those with a haemangiopericytomatous pattern.

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