Small cell neuroendocrine tumour of the cervix in pregnancy: the importance of multidisciplinary management

A woman in her mid-20s presented with bleeding at 18 weeks gestation from a cervical ‘polyp’. Histopathology demonstrated a rare small cell neuroendocrine of the cervix. There were only 18 cases of neuroendocrine tumours of the cervix in and around pregnancy in the literature, so the evidence base for treatment was scarce. She was treated with neoadjuvant chemotherapy, using a regimen used for small cell neuroendocrine tumours of the lung, to allow for fetal lung maturity. Disease initially responded, then progressed and she was delivered at 32 weeks by caesarean radical hysterectomy. Adjuvant treatment included further chemotherapy and radical pelvic radiotherapy. The woman and her child are doing well over 6 years after treatment, although the woman has significant side effects of both radical surgery and radiotherapy. This case emphasises the need for excellent communication between multidisciplinary professionals, patients and their families and using external colleagues to help with rare clinical problems.

A Case Of Giant Cervical Polyp

Introduction: Cervical polyps are small pedunculate, often sessile neoplasm of the cervix. It is not known whether this is due to chronic inflammation, or abnormal local responsiveness to hormonal stimulation, or localized vascular congestion of cervical blood vessels. They occur most frequently in multiparous women in the fifth decade of life. Case Description: Here, we are reporting a case of a giant cervical polyp in a 38-year-old nulliparous lady who reported heavy menstrual bleeding and mass per vagina. Conclusion: Giant cervical polyp can mimic chronic inversion of the uterus, cervical fibroid, endometrial polyp, and cervical malignancy.

Polypoid Endometriosis of Cervix: A Case Report

Polypoid endometriosis is an uncommon and distinctive variant of endometriosis with histologic features simulating those of an endometrial polyp which is found most often in the colon and ovary. The cervix is an infrequent site for polypoid endometriosis. We report a 40-year-old female presented with irregular bleeding and on examination detected to have an endocervical polyp. She underwent polypectomy and histopathological examination suggested polypoid endometriosis. She remained asymptomatic during two years of follow-up.Polypoid endometriosis is a variant of endometriosis that may be mistaken for a neoplasm on clinical and pathologic examination. There is often a delay in diagnosis resulting in unnecessary suffering and reduced quality of life. Though a rare entity, it should be considered in the differential diagnosis of all cervical polyp.

Case Report: Adenocarcinoma Of The Appendix Presenting As A Cervical Polyp.

Background: The differential diagnosis of a vaginal mass after hysterectomy is broad. Malignancies of the genital tract or metastasis from another primary tumor should be excluded. Appendiceal carcinoma is a rare cause, case reports are limited.Case presentation: A 77-year-old woman with a history of vaginal hysterectomy presented with a 12-month history of vaginal pressure. The vaginal mass, penetrating trough the cervix, is resected (vaginal approach). A Microscopic examination of the removed tissue revealed an adenocarcinoma of the appendix. Right hemicolectomy, resection of the vaginal vault and resection of the regional lymph nodes showed no residual tumor.Conclusions: Full diagnostic work-up of a vaginal mass should be performed to avoid unexpected malignancy. Transvaginal resection was in this case feasible and safe.

RECURRENT POLYP REVEALING A RARE CASE OF CERVICAL RHABDOMYOSARCOMA: ABOUT A CASE AND REVIEW OF THE LITERATURE

Rhabdomyosarcoma of the uterine cervix is one of the rare histological types of cervical cancer, which occurs mainly in girls and women during genital activity. Given the aggressiveness of the disease, therapeutic strategy is based on the combination of the three treatment modalities (surgery -chemotherapy radiation therapy-).We report a case of cervical rhabdomyosarcoma in a 53 year old woman with no particular pathological history. The first sign reported was postmenopausal metrorrhagia with the presence of a cervical polyp. The bistourning of this polyp was in favour of cervical adenosarcoma. The extension workup showed a cervical mass without metastasis. The patient underwent surgery and underwent a hysterectomy without preservation of adnexae with anatomopathologic results that suggested a cervical rhabdomyosarcoma and a candidate for adjuvant chemo-radiotherapy. Rhabdomyosarcoma of the uterine cervix is a rare tumor that develops most often in young girls. It mainly shows locoregional extension. Treatment is based on surgery including conservative treatment as well as radical treatment associated with perioperative chemotherapy. The role of radiation therapy remains poorly defined.

S. Voino. - Report on the surgical activity of S. V. Topuria's medical school in the city of Kutais from May 1, 1890 to May 1, 1894. SPb. 1895 year

This hospital also provides assistance to gynecological patients. During the reporting period, 717 operations were performed in her outpatient clinic, including 17 gynecological operations (discisio coli uteri 2, excisio condylomatum 11, removal of cervical polyp 3 and removal of cervical cancer 1).