scholarly journals Assessment of the effectiveness of the EUROFORGEN NAME and Precision ID Ancestry panel markers for ancestry investigations

Author(s):  
Ditte Truelsen ◽  
Torben Tvedebrink ◽  
Helle Smidt Mogensen ◽  
Maryam Sharafi Farzad ◽  
Muhammad Adnan Shan ◽  
...  

Abstract The EUROFORGEN NAME panel is a second-tier ancestry panel designed to differentiate individuals from the Middle East, North Africa, and Europe. The first version of the panel was developed for the MassARRAY® system and included 111 SNPs. Here, a custom AmpliSeq™ EUROFORGEN NAME panel with 102 of the original 111 loci was used to sequence 1,098 individuals from 14 populations from Europe, the Middle East, North Africa, North-East Africa, and South-Central Asia. These samples were also sequenced with the first-tier Precision ID Ancestry Panel. The GenoGeographer software was used to assign the AIM profiles to reference populations and calculate the weight of the evidence as likelihood ratios. The combination of the EUROFORGEN NAME and Precision ID Ancestry panels led to fewer ambiguous assignments, especially for individuals from the Middle East and South-Central Asia. The likelihood ratios showed that North African individuals could be separated from European and Middle Eastern individuals using the Precision ID Ancestry Panel. The separation improved with the addition of the EUROFORGEN NAME panel. The analyses also showed that the separation of Middle Eastern populations from European and South-Central Asian populations was challenging even when both panels were applied.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
D. Truelsen ◽  
T. Tvedebrink ◽  
H. S. Mogensen ◽  
M. S. Farzad ◽  
M. A. Shan ◽  
...  

AbstractThe EUROFORGEN NAME panel is a regional ancestry panel designed to differentiate individuals from the Middle East, North Africa, and Europe. The first version of the panel was developed for the MassARRAY system and included 111 SNPs. Here, a custom AmpliSeq EUROFORGEN NAME panel with 102 of the original 111 loci was used to sequence 1098 individuals from 14 populations from Europe, the Middle East, North Africa, North-East Africa, and South-Central Asia. These samples were also sequenced with a global ancestry panel, the Precision ID Ancestry Panel. The GenoGeographer software was used to assign the AIM profiles to reference populations and calculate the weight of the evidence as likelihood ratios. The combination of the EUROFORGEN NAME and Precision ID Ancestry panels led to fewer ambiguous assignments, especially for individuals from the Middle East and South-Central Asia. The likelihood ratios showed that North African individuals could be separated from European and Middle Eastern individuals using the Precision ID Ancestry Panel. The separation improved with the addition of the EUROFORGEN NAME panel. The analyses also showed that the separation of Middle Eastern populations from European and South-Central Asian populations was challenging even when both panels were applied.


2002 ◽  
Vol 1 (1) ◽  
pp. 3-21 ◽  
Author(s):  
EMILE SAHLIYEH ◽  
SANGEETA SINHA ◽  
VIJAYAN PILLAI

ABSTRACT Theory: Literature on ethnic protest in the Middle East and Central Asia does not provide empirical measures necessary for rigorous hypothesis testing, nor does it incorporate a comprehensive theoretical foundation needed to identify the conditions for ethnic protest. There is also no consensus on the causes of ethnic protest in the Middle East and Central Asia. Hypotheses: To improve our ability to explain ethnic protest in the Middle East and Central Asia and to identify the necessary conditions for ethnic dissent, we test five hypotheses embodied in grievance and political mobilization. The literature on ethnic protest in the Middle East and Central Asia references both models but does not systematically test their relevance. Methodology: We use Logistic Regression to test the explanatory potential of the five hypotheses of the Grievance and Mobilization models. We use Ted Gurr's Minorities at Risk data set, which presents data on 40 ethnic groups in the Middle East and Central Asia. The dependent variable is protest for 1990-95. Findings: Our research does not lend much empirical support for the grievance model, which dominates the Middle Eastern and Central Asian area study literature. Cultural identity and religious freedom variables of grievance model do not provide sufficient condition for the outbreak of ethnic protest. The mobilization model has better explanatory power. It lends significant support to the three hypotheses associated with the mobilization model and suggests that ethnic protest is more likely to occur under conditions of organizational cohesiveness, low levels of autocracy, and international support.


Author(s):  
Emma Taylor ◽  
Victor Del Rio Vilas ◽  
Terence Scott ◽  
Andre Coetzer ◽  
Joaquin M. Prada ◽  
...  

2011 ◽  
Vol 43 (2) ◽  
pp. 317-319
Author(s):  
Paul Thomas Chamberlin

The new Cold War history has begun to reshape the ways that international historians approach the Middle East and North Africa (MENA) during the post-1945 era. Rather than treating the region as exceptional, a number of scholars have sought to focus on the historical continuities and transnational connections between the Middle East and other areas of the Third World. This approach is based on the notion that the MENA region was enmeshed in the transnational webs of communication and exchange that characterized the post-1945 global system. Indeed, the region sat not only at the crossroads between Africa and the Eurasian landmass but also at the convergence of key global historical movements of the second half of the 20th century. Without denying cultural, social, and political elements that are indeed unique to the region, this scholarship has drawn attention to the continuities, connections, and parallels between the Middle Eastern experience and the wider world.


2019 ◽  
Vol 9 (24) ◽  
Author(s):  
Hichem Dkhili

Background. Studies on environmental performance/quality and economic growth show inconclusive results. Objective. The aim of the present study is to assess the non-linear relationship between environmental performance and economic growth in the Middle East and North Africa (MENA) region from 2002–2018. Methods. A sample of fourteen (14) MENA countries was used in the present analysis. However, due to important differences between countries in this region, the whole sample was divided into two sub-samples; nine Middle Eastern countries (MEAS) and five North African countries (NAF). We performed the panel smooth transition regression model as an econometric approach. Discussion. Empirical results indicate a threshold effect in the environmental performance and economic growth relationship. The threshold value differs from one group of countries to another. More specifically, we found that the impact of environmental performance and economic growth is positive and significant only if a certain threshold level has been attained. Until then, the effect remains negative. Conclusions. The findings of the present study are of great importance for policymakers since they determine the optimal level of environmental performance required to act positively on the level of economic growth. MENA countries should seek to improve their environmental performance index in order to grow output. Competing Interests. The authors declare no competing financial interests.


Author(s):  
Christopher I. Beckwith

This chapter examines Islamization in Classical Arabic Central Asia. The Arab Empire founded by the prophet Muhammad expanded rapidly, defeating the Byzantine Empire and capturing Syria (637) and Egypt (640). At the same time, the Arabs defeated the Sasanid Persian Empire (637) and raced across Persia into Central Asia. Within a very short time, early Arab Islamic culture came into direct, intimate contact with several major civilized areas, including the Graeco-Roman-influenced cultures of the Levant and North Africa, Persian culture, and the Buddhist cultures of Central Asia. From them the Muslims adopted various cultural elements. This chapter considers when, where, and how the Muslims acquired the recursive argument method and the Islamic college or madrasa. It shows that the recursive argument method is used in Arabic works by the Central Asian scientist and philosopher Avicenna.


Author(s):  
Maud S. Mandel

Beginning in 1948 when war in the Middle East caused minor unrest in the city of Marseille, this chapter traces the way in which disagreements over Israel became a way to debate inequities in French minority policies at home and in North Africa. In Marseille, the gathering point for Jewish clandestine migration to Palestine, Algerian Muslims' anger toward what they perceived as French complicity in migration schemes was compounded by frustrations that French officials seemed to be favoring Jewish refugees over newly minted French Algerian Muslim citizens. Conflicts around war in the Middle East thus became an opportunity for politically active Muslims and Jews to negotiate their relationship with the French state, as the former established new parameters for political participation in the aftermath of the Holocaust by pushing the French government to support Israel, and the latter tested the limitations on a citizenship that never made good on its promises.


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