scholarly journals Assessment of the effectiveness of the EUROFORGEN NAME and Precision ID Ancestry panel markers for ancestry investigations

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
D. Truelsen ◽  
T. Tvedebrink ◽  
H. S. Mogensen ◽  
M. S. Farzad ◽  
M. A. Shan ◽  
...  

AbstractThe EUROFORGEN NAME panel is a regional ancestry panel designed to differentiate individuals from the Middle East, North Africa, and Europe. The first version of the panel was developed for the MassARRAY system and included 111 SNPs. Here, a custom AmpliSeq EUROFORGEN NAME panel with 102 of the original 111 loci was used to sequence 1098 individuals from 14 populations from Europe, the Middle East, North Africa, North-East Africa, and South-Central Asia. These samples were also sequenced with a global ancestry panel, the Precision ID Ancestry Panel. The GenoGeographer software was used to assign the AIM profiles to reference populations and calculate the weight of the evidence as likelihood ratios. The combination of the EUROFORGEN NAME and Precision ID Ancestry panels led to fewer ambiguous assignments, especially for individuals from the Middle East and South-Central Asia. The likelihood ratios showed that North African individuals could be separated from European and Middle Eastern individuals using the Precision ID Ancestry Panel. The separation improved with the addition of the EUROFORGEN NAME panel. The analyses also showed that the separation of Middle Eastern populations from European and South-Central Asian populations was challenging even when both panels were applied.

2021 ◽  
Author(s):  
Ditte Truelsen ◽  
Torben Tvedebrink ◽  
Helle Smidt Mogensen ◽  
Maryam Sharafi Farzad ◽  
Muhammad Adnan Shan ◽  
...  

Abstract The EUROFORGEN NAME panel is a second-tier ancestry panel designed to differentiate individuals from the Middle East, North Africa, and Europe. The first version of the panel was developed for the MassARRAY® system and included 111 SNPs. Here, a custom AmpliSeq™ EUROFORGEN NAME panel with 102 of the original 111 loci was used to sequence 1,098 individuals from 14 populations from Europe, the Middle East, North Africa, North-East Africa, and South-Central Asia. These samples were also sequenced with the first-tier Precision ID Ancestry Panel. The GenoGeographer software was used to assign the AIM profiles to reference populations and calculate the weight of the evidence as likelihood ratios. The combination of the EUROFORGEN NAME and Precision ID Ancestry panels led to fewer ambiguous assignments, especially for individuals from the Middle East and South-Central Asia. The likelihood ratios showed that North African individuals could be separated from European and Middle Eastern individuals using the Precision ID Ancestry Panel. The separation improved with the addition of the EUROFORGEN NAME panel. The analyses also showed that the separation of Middle Eastern populations from European and South-Central Asian populations was challenging even when both panels were applied.


2012 ◽  
Vol 15 (10) ◽  
pp. 1835-1844 ◽  
Author(s):  
Mahdieh Golzarand ◽  
Parvin Mirmiran ◽  
Mahsa Jessri ◽  
Karamollah Toolabi ◽  
Mehdi Mojarrad ◽  
...  

AbstractObjectiveMiddle Eastern and North African countries are undergoing nutrition transition, a transition which is associated with an increased burden of non-communicable diseases. This necessitates the evaluation of dietary patterns in these regions. The present study aimed to assess changes in dietary patterns in Middle Eastern and North African countries between 1961 and 2007.DesignAvailability of energy and fifteen main food items during 1961–2007 was examined using FAO food balance sheets from the FAOSTAT database.SettingFifteen countries including nine in the Middle East and six in North Africa were selected and the average availability of total energy and different food items in these regions were compared.ResultsOver the 47 years studied, energy and food availability (apart from animal fats and alcoholic beverages) has increased in the Middle East and North Africa. In both regions the proportion of energy derived from meat and vegetable oils has increased significantly while that from cereals decreased significantly. In addition, the proportion of energy from milk and dairy products and vegetables has shown an ascending trend in North Africa while the proportion of energy from fruits has shown a descending trend in the Middle East.ConclusionsThe study results reveal an unfavourable trend towards a Westernized diet in the Middle East and, to a certain extent, in North Africa. Tailored nutritional education encouraging healthy eating for prevention of the burden of chronic diseases in these countries seems essential.


2002 ◽  
Vol 1 (1) ◽  
pp. 3-21 ◽  
Author(s):  
EMILE SAHLIYEH ◽  
SANGEETA SINHA ◽  
VIJAYAN PILLAI

ABSTRACT Theory: Literature on ethnic protest in the Middle East and Central Asia does not provide empirical measures necessary for rigorous hypothesis testing, nor does it incorporate a comprehensive theoretical foundation needed to identify the conditions for ethnic protest. There is also no consensus on the causes of ethnic protest in the Middle East and Central Asia. Hypotheses: To improve our ability to explain ethnic protest in the Middle East and Central Asia and to identify the necessary conditions for ethnic dissent, we test five hypotheses embodied in grievance and political mobilization. The literature on ethnic protest in the Middle East and Central Asia references both models but does not systematically test their relevance. Methodology: We use Logistic Regression to test the explanatory potential of the five hypotheses of the Grievance and Mobilization models. We use Ted Gurr's Minorities at Risk data set, which presents data on 40 ethnic groups in the Middle East and Central Asia. The dependent variable is protest for 1990-95. Findings: Our research does not lend much empirical support for the grievance model, which dominates the Middle Eastern and Central Asian area study literature. Cultural identity and religious freedom variables of grievance model do not provide sufficient condition for the outbreak of ethnic protest. The mobilization model has better explanatory power. It lends significant support to the three hypotheses associated with the mobilization model and suggests that ethnic protest is more likely to occur under conditions of organizational cohesiveness, low levels of autocracy, and international support.


2019 ◽  
Vol 116 (5) ◽  
pp. 1651-1658 ◽  
Author(s):  
Jonathan M. Flowers ◽  
Khaled M. Hazzouri ◽  
Muriel Gros-Balthazard ◽  
Ziyi Mo ◽  
Konstantina Koutroumpa ◽  
...  

Date palm (Phoenix dactylifera L.) is a major fruit crop of arid regions that were domesticated ∼7,000 y ago in the Near or Middle East. This species is cultivated widely in the Middle East and North Africa, and previous population genetic studies have shown genetic differentiation between these regions. We investigated the evolutionary history of P. dactylifera and its wild relatives by resequencing the genomes of date palm varieties and five of its closest relatives. Our results indicate that the North African population has mixed ancestry with components from Middle Eastern P. dactylifera and Phoenix theophrasti, a wild relative endemic to the Eastern Mediterranean. Introgressive hybridization is supported by tests of admixture, reduced subdivision between North African date palm and P. theophrasti, sharing of haplotypes in introgressed regions, and a population model that incorporates gene flow between these populations. Analysis of ancestry proportions indicates that as much as 18% of the genome of North African varieties can be traced to P. theophrasti and a large percentage of loci in this population are segregating for single-nucleotide polymorphisms (SNPs) that are fixed in P. theophrasti and absent from date palm in the Middle East. We present a survey of Phoenix remains in the archaeobotanical record which supports a late arrival of date palm to North Africa. Our results suggest that hybridization with P. theophrasti was of central importance in the diversification history of the cultivated date palm.


2000 ◽  
Vol 34 (1) ◽  
pp. 23-36
Author(s):  
Miyazi Kazuo

The Purpose of this Paper is to present the history and the present status of Middle Eastern and North African Studies in Japan. As the status of the studies is closely related to the status of the relationships between Japan and the regions concerned, I will first write about the history of Japan-Middle East (including North Africa) relations and the relationship thereof to the studies.


2007 ◽  
Vol 88 (3) ◽  
pp. 967-980 ◽  
Author(s):  
Dan David ◽  
Gareth J. Hughes ◽  
Boris A. Yakobson ◽  
Irit Davidson ◽  
Hikmat Un ◽  
...  

Four novel phylogenetic clades of canine rabies virus (RABV) variants have been identified in the Middle East and North Africa. The three novel Middle Eastern clades comprise RABV isolates from the borders between Israel and neighbouring countries. The North African clade (Africa 4) comprises four RABV isolates from Egypt and one from Israel. We characterized various RABV lineages antigenically by using a panel of monoclonal antibodies to the nucleoprotein (N) and phylogenetically by analysis of entire N gene sequences. The estimated mean substitution rate for the N gene alignment (2.7×10−4 substitutions per site per year) is comparable with previous estimates for RABV. The application of a molecular clock indicates the emergence of current canine RABV diversity to have occurred at about the same time (approx. 1870) in the Middle East and Europe, following divergence from established lineages in Africa and Asia.


2015 ◽  
Vol 11 (2) ◽  
Author(s):  
Anna K. Raggl

AbstractA decomposition of output growth rates of Middle Eastern and North African countries shows that the contributions of human capital-augmented labor and physical capital to output growth are comparably small and stable over time and that in most countries a considerable share of output growth is attributed to growth in total factor productivity. This paper empirically assesses the determinants of total factor productivity in the Middle East and North Africa region between 1980 and 2009. The findings suggest that human capital is not only an input factor of production but also a quantity that changes the efficiency by which existing input factors are used. Domestic innovations appear to be efficient only if a certain level of educational attainment is reached by a country. In addition, human capital contributes to the ability of efficient adoption of technology from abroad and allows a faster catch-up with technological leaders. Globalization, in combination with a (comparably low) threshold endowment of human capital, is estimated to increase total factor productivity in Middle Eastern and North African countries.


Screen Bodies ◽  
2017 ◽  
Vol 2 (2) ◽  
pp. 64-77 ◽  
Author(s):  
Walter S. Temple

In recent years, North African queer cinema has become increasingly visible both within and beyond Arabo-Orientale spaces. A number of critical factors have contributed to a global awareness of queer identities in contemporary Maghrebi cinema, including the dissemination of films through social media outlets and during international film festivals. Such tout contemporain representations of queer sexuality characterize a robust wave of films in the Middle East and North Africa (MENA) region, inciting a new discourse on the condition of the marginalized traveler struggling to locate new forms of self and being—both at home and abroad.


Author(s):  
Emma Taylor ◽  
Victor Del Rio Vilas ◽  
Terence Scott ◽  
Andre Coetzer ◽  
Joaquin M. Prada ◽  
...  

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