scholarly journals Atherogenic index of plasma is associated with the severity of Hidradenitis Suppurativa: a case-control study

2020 ◽  
Author(s):  
José Luis Hernández ◽  
Cristina Baldeón ◽  
Ana Elísabet López-Sundh ◽  
J Gonzalo Ocejo-Vinyals ◽  
Ricardo Blanco ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Hidradenitis Suppurativa ◽  
Case Control Study ◽  
Case Control ◽  
Atherogenic Index ◽  
Control Group ◽  
Physician Global Assessment ◽  
Atherogenic Index Of Plasma ◽  
Control Study ◽  
Statin Use

Abstract Background. Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with several comorbidities and vascular risk factors, such as dyslipidemia. The present study aimed to assess the possible associations between the lipid profile and atherogenic indexes and the severity of HS. Methods. This case-control study enrolled 78 HS patients and 62 healthy controls. Classic lipid profile and lipoprotein ratios, including the atherogenic index of plasma (AIP), were evaluated. The severity of HS was measured by the HS Physician Global Assessment (PGA). Results. HS-patients had lower serum total cholesterol and HDL-C levels and higher AIP than the control group. AIP was positively correlated to BMI, waist circumference, systolic and diastolic blood pressure, LDL-C, triglycerides, non-HDL-C, ApoB, HOMA, and hs-CRP and negatively to HDL-C and ApoA1. For the overall lipid profile, only AIP was related to a more severe HS (PGA≥3) after controlling for age, sex, BMI, insulin resistance (IR), active smoking, and statin use (r=0.268; p=0.023). Multiple logistic regression adjusted for age, sex, BMI, IR, smoking status and statin use, showed that AIP≥0.5 was significantly associated with the severity of HS (OR, 4.38; CI 95%, 1.09-17.50; p=0.037). Conclusions. In conclusion, these results showed that AIP is significantly and independently associated with HS severity.

scholarly journals Atherogenic Index of Plasma is Associated with the Severity of Hidradenitis Suppurativa: A Case Control Study

2020 ◽  
Author(s):  
José Luis Hernández ◽  
Cristina Baldeón ◽  
Ana Elísabet López-Sundh ◽  
J Gonzalo Ocejo-Vinyals ◽  
Ricardo Blanco ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Hidradenitis Suppurativa ◽  
Case Control Study ◽  
Case Control ◽  
Atherogenic Index ◽  
Control Group ◽  
Physician Global Assessment ◽  
Atherogenic Index Of Plasma ◽  
Control Study ◽  
Statin Use

Abstract Background. Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with several comorbidities and vascular risk factors, such as dyslipidemia. The aim of the present study was to assess the possible associations between the lipid profile and atherogenic indexes and the severity of HS. Methods. This case-control study enrolled 78 HS patients and 62 healthy controls. Classic lipid profile and lipoprotein ratios, including the atherogenic index of plasma (AIP) (log10[triglycerides/HDL-c]) were evaluated. Severity of HS was measured by the HS Physician Global Assessment (PGA). Results. HS-patients had lower serum total cholesterol and HDL-c levels and higher AIP than the control group. AIP was positively correlated to BMI, waist perimeter, systolic and diastolic blood pressure, LDL-c, triglycerides, non-HDL-C, ApoB, HOMA and hs-CRP and negatively to HDL-c and ApoA1. For the overall lipid profile, only AIP was related to a more severe HS (PGA≥3) after controlling for age, sex, BMI, insulin resistance (IR), active smoking and statin use (r=0.268; p=0.023). Multivariable logistic regression adjusted for age, sex, BMI, IR, smoking status and statin use, showed that AIP≥0.5 was significantly associated with the severity of HS (OR, 4.38; CI 95%, 1.09-17.50; p=0.037). Conclusions. In conclusion, our results showed that AIP was significantly and independently associated with HS severity.

scholarly journals Atherogenic index of plasma is associated with the severity of Hidradenitis Suppurativa: a case-control study

2020 ◽  
Author(s):  
José Luis Hernández ◽  
Cristina Baldeón ◽  
Ana Elísabet López-Sundh ◽  
J Gonzalo Ocejo-Vinyals ◽  
Ricardo Blanco ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Hidradenitis Suppurativa ◽  
Case Control Study ◽  
Case Control ◽  
Atherogenic Index ◽  
Control Group ◽  
Physician Global Assessment ◽  
Atherogenic Index Of Plasma ◽  
Control Study ◽  
Statin Use

Abstract Background. Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with several comorbidities and vascular risk factors, such as dyslipidemia. The present study aimed to assess the possible associations between the lipid profile and atherogenic indexes and the severity of HS. Methods . This case-control study enrolled 78 HS patients and 62 healthy controls. Classic lipid profile and lipoprotein ratios, including the atherogenic index of plasma (AIP), were evaluated. The severity of HS was measured by the HS Physician Global Assessment (PGA). Results . HS-patients had lower serum total cholesterol and HDL-C levels and higher AIP than the control group. AIP was positively correlated to BMI, waist circumference, systolic and diastolic blood pressure, LDL-C, triglycerides, non-HDL-C, ApoB, HOMA, and hs-CRP and negatively to HDL-C and ApoA1. For the overall lipid profile, only AIP was related to a more severe HS (PGA≥3) after controlling for age, sex, BMI, insulin resistance (IR), active smoking, and statin use (r=0.268; p=0.023). Multiple logistic regression adjusted for age, sex, BMI, IR, smoking status and statin use, showed that AIP≥0.11 was significantly associated with the severity of HS (OR, 4.38; CI 95%, 1.09-17.50; p=0.037). Conclusions . In conclusion, these results showed that AIP is significantly and independently associated with HS severity.

scholarly journals The correlation between dietary fat quality indices and lipid profile with Atherogenic Index of Plasma in obese and non-obese Volunteers: a cross-sectional descriptive-analytic case-control study

2020 ◽  
Author(s):  
Maryam sadat Mousavi javardi ◽  
Zahra Madani ◽  
Majid Karandish ◽  
Ariyo Movahedi ◽  
Behnood Abbasi
Keyword(s):  
Lipid Profile ◽  
Dietary Fat ◽  
Case Control Study ◽  
Case Control ◽  
Atherogenic Index ◽  
Quality Indices ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Fat Quality ◽  
Control Study

Abstract Background and aim: Abnormalities in lipid metabolism are commonly observed in patients who were obese. Alongside dyslipidemia, one of the markers in predicting the risk of cardiovascular disease is the Atherogenic Index of Plasma (AIP), which is related to dietary intake. Healthy fat quality indices might affect on AIP. The purpose of this study is to find the possible relationship between dietary fat quality, and AIP and comparison of these indices among obese and non-obese volunteers.Methods: This study was a cross-sectional descriptive-analytic case-control study with 157 normal and overweight and obese volunteers (n=71 normal, Age: 38.90±10.976 vs n=86 overweight/obese, Age: 38.60±9.394) in the age range of 18-65 years. Food intake was measured using FFQ, anthropometric indices (weight, height, body mass index and waist to hip ratio), body composition (visceral fat level, total body water, body fat mass), and lipid profile were measured.Results: Based on the present results, comparable biochemical parameters including TC (P=0.580), TG (P=0.362), LDL (P=0.687) and HDL (P=0.151) among overweight/obese volunteers as compared to normal ones were noticed. Effects of dietary fat quality, including Atherogenicity (AI) and Thrombogenicity (TI) hypo/hypercholesterolemic ratio (h/H), the Cholesterol-Saturated Fat Index (CSI) showed significantly higher AI (P=0.012) in the overweight/obese group as compared to the normal group. Whereas, h/H (P=0.034) and ω-6/ω-3 ratio (P=0.004) were significantly higher in normal-weight volunteers. There was a positive correlation between AI, TI, CSI, SFA, MUFA, PUFA and ω-6/ω-3 ratio with AIP and negative correlation between h/H with AIP in both groups. Despite the significances of these correlations no strong relation was observed by doing multiple regression among normal and overweight/obese groups (R2=0.210, R2=0.387).Conclusions: In summary, the present work proposes a direct relationship between dietary fat quality, increased BMI, and lipid abnormalities with AIP. Nevertheless, further large-scale studies are required to sustain a clear conclusion in this wish.

scholarly journals The correlation between dietary fat quality indices and lipid profile with Atherogenic Index of Plasma in obese and non-obese Volunteers: a cross-sectional descriptive-analytic case-control study

2020 ◽  
Author(s):  
Maryam sadat Mousavi javardi ◽  
Zahra Madani ◽  
Majid Karandish ◽  
Ariyo Movahedi ◽  
Behnood Abbasi
Keyword(s):  
Lipid Profile ◽  
Dietary Fat ◽  
Case Control Study ◽  
Case Control ◽  
Atherogenic Index ◽  
Quality Indices ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Fat Quality ◽  
Control Study

Abstract Background and aim: Abnormalities in lipid metabolism are commonly observed in patients who were obese. Alongside dyslipidemia, one of the markers in predicting the risk of cardiovascular disease is the Atherogenic Index of Plasma (AIP), which is related to dietary intake. Healthy fat quality indices might affect on AIP. The purpose of this study is to find the possible relationship between dietary fat quality, and AIP and comparison of these indices among obese and non-obese volunteers.Methods: This study was a cross-sectional descriptive-analytic case-control study with 157 normal and overweight and obese volunteers (n=71 normal, Age: 38.90±10.976 vs n=86 overweight/obese, Age: 38.60±9.394) in the age range of 18-65 years. Food intake was measured using FFQ, anthropometric indices (weight, height, body mass index and waist to hip ratio), body composition (visceral fat level, total body water, body fat mass), and lipid profile were measured. Results: Based on the present results, comparable biochemical parameters including TC (P=0.580), TG (P=0.362), LDL (P=0.687) and HDL (P=0.151) among overweight/obese volunteers as compared to normal ones were noticed. Effects of dietary fat quality, including Atherogenicity (AI) and Thrombogenicity (TI) hypo/hypercholesterolemic ratio (h/H), the Cholesterol-Saturated Fat Index (CSI) showed significantly higher AI (P=0.012) in the overweight/obese group as compared to the normal group. Whereas, h/H (P=0.034) and ω-6/ω-3 ratio (P=0.004) were significantly higher in normal-weight volunteers. There was a positive correlation between AI, TI, CSI, SFA, MUFA, PUFA and ω-6/ω-3 ratio with AIP and negative correlation between h/H with AIP in both groups. Despite the significances of these correlations no strong relation was observed by doing multiple regression among normal and overweight/obese groups (R2=0.210, R2=0.387).Conclusions: In summary, the present work proposes a direct relationship between dietary fat quality, increased BMI, and lipid abnormalities with AIP. Nevertheless, further large-scale studies are required to sustain a clear conclusion in this wish.

scholarly journals The correlation between dietary fat quality indices and lipid profile with Atherogenic index of plasma in obese and non-obese volunteers: a cross-sectional descriptive-analytic case-control study

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Maryam Sadat Moussavi Javardi ◽  
Zahra Madani ◽  
Ariyo Movahedi ◽  
Majid Karandish ◽  
Behnood Abbasi
Keyword(s):  
Lipid Profile ◽  
Dietary Fat ◽  
Case Control Study ◽  
Case Control ◽  
Atherogenic Index ◽  
Quality Indices ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Fat Quality ◽  
Control Study

Abstract Background and aim Abnormalities in lipid metabolism are commonly observed in patients who were obese. Alongside dyslipidemia, one of the markers in predicting the risk of cardiovascular disease is the Atherogenic Index of Plasma (AIP), which is related to dietary intake. Healthy fat quality indices might affect on AIP. The purpose of this study is to find the possible relationship between dietary fat quality, and AIP and comparison of these indices among obese and non-obese volunteers. Methods This study was a cross-sectional descriptive-analytic case-control study with 157 normal and overweight and obese volunteers (n = 71 normal, Age: 38.90 ± 10.976 vs n = 86 overweight/obese, Age: 38.60 ± 9.394) in the age range of 18–65 years. Food intake was measured using FFQ, anthropometric indices (weight, height, body mass index and waist to hip ratio), body composition (visceral fat level, total body water, body fat mass), and lipid profile were measured. Results Based on the present results, comparable biochemical parameters including TC (P = 0.580), TG (P = 0.362), LDL (P = 0.687) and HDL (P = 0.151) among overweight/obese volunteers as compared to normal ones were noticed. Effects of dietary fat quality, including Atherogenicity (AI) and Thrombogenicity (TI) hypo/hypercholesterolemic ratio (h/H), the Cholesterol-Saturated Fat Index (CSI) showed significantly higher AI (P = 0.012) in the overweight/obese group as compared to the normal group. Whereas, h/H (P = 0.034) and ω-6/ω-3 ratio (P = 0.004) were significantly higher in normal-weight volunteers. There was a positive correlation between AI, TI, CSI, SFA, MUFA, PUFA and ω-6/ω-3 ratio with AIP and negative correlation between h/H with AIP in both groups. Despite the significances of these correlations no strong relation was observed by doing multiple regression among normal and overweight/obese groups (R2 = 0.210, R2 = 0.387). Conclusions In summary, the present work proposes a direct relationship between dietary fat quality, increased BMI, and lipid abnormalities with AIP. Nevertheless, further large-scale studies are required to sustain a clear conclusion in this wish.

scholarly journals The correlation between dietary fat quality indices and lipid profile with Atherogenic Index of Plasma in obese and non-obese Volunteers: a cross-sectional descriptive-analytic case-control study

2020 ◽  
Author(s):  
Maryam sadat Mousavi javardi ◽  
Zahra Madani ◽  
Majid Karandish ◽  
Ariyo Movahedi ◽  
Behnood Abbasi
Keyword(s):  
Lipid Profile ◽  
Dietary Fat ◽  
Case Control Study ◽  
Case Control ◽  
Atherogenic Index ◽  
Quality Indices ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Fat Quality ◽  
Control Study

Abstract Background and aim: Abnormalities in lipid metabolism are commonly observed in patients who were obese. Alongside dyslipidemia, one of the markers in predicting the risk of cardiovascular disease is the Atherogenic Index of Plasma (AIP), which is related to dietary intake. Healthy fat quality indices might affect on AIP. The purpose of this study is to find the possible relationship between dietary fat quality, and AIP and comparison of these indices among obese and non-obese volunteers. Methods: This study was a cross-sectional descriptive-analytic case-control study with 157 normal and overweight and obese volunteers (n=71 normal, Age: 38.90±10.976 vs n=86 overweight/obese, Age: 38.60±9.394) in the age range of 18-65 years. Food intake was measured using FFQ, anthropometric indices (weight, height, body mass index and waist to hip ratio), body composition (visceral fat level, total body water, body fat mass), and lipid profile were measured. Results: Based on the present results, comparable biochemical parameters including TC (P=0.580), TG (P=0.362), LDL (P=0.687) and HDL (P=0.151) among overweight/obese volunteers as compared to normal ones were noticed. Results of dietary fat quality, including Atherogenicity (AI) and Thrombogenicity (TI) hypo/hypercholesterolemic ratio (h/H), the Cholesterol-Saturated Fat Index (CSI) showed significantly higher AI (P=0.012) in the overweight/obese group as compared to the normal group. Whereas, h/H (P=0.034) and ω-6/ω-3 ratio (P=0.004) were significantly higher in normal-weight volunteers. There was a positive correlation between AI, TI, CSI, SFA, MUFA, PUFA and ω-6/ω-3 ratio with AIP and negative correlation between h/H with AIP in both groups. Despite the significancies of these correlations no strong relation was observed by doing multiple regression among normal and overweight/obese groups (R2=0.210, R2=0.387). Conclusions: In summary, the present study suggests a direct relationship between dietary fat quality, increased BMI, and lipid abnormalities with AIP. However, further large-scale studies are needed to have a clear conclusion in this regard.

scholarly journals Atherogenic index of plasma is associated with the severity of Hidradenitis Suppurativa: a case-control study

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
José L. Hernández ◽  
Cristina Baldeón ◽  
Ana E. López-Sundh ◽  
J. Gonzalo Ocejo-Vinyals ◽  
Ricardo Blanco ◽  
...  
Keyword(s):  
Hidradenitis Suppurativa ◽  
Case Control Study ◽  
Case Control ◽  
Atherogenic Index ◽  
Atherogenic Index Of Plasma ◽  
Control Study

scholarly journals The correlation between dietary fat quality indices and lipid profile with Atherogenic Index of Plasma in obese and non-obese Volunteers: a cross-sectional descriptive-analytic case-control study

2020 ◽  
Author(s):  
Maryam sadat Mousavi javardi ◽  
Zahra Madani ◽  
Majid Karandish ◽  
Ariyo Movahedi ◽  
Behnood Abbasi
Keyword(s):  
Dietary Fat ◽  
Case Control Study ◽  
Saturated Fat ◽  
Case Control ◽  
Atherogenic Index ◽  
Quality Indices ◽  
Cross Sectional ◽  
Atherogenic Index Of Plasma ◽  
Fat Quality ◽  
Control Study

Abstract Background and aim: Abnormalities in lipid metabolism are commonly observed in patients who were obese. Alongside dyslipidemia, one of the markers in predicting the risk of cardiovascular disease is the Atherogenic Index of Plasma (AIP), which is related to dietary intake. Healthy fat quality indices, including Atherogenicity (AI) and Thrombogenicity (TI) hypo/hypercholesterolemic ratio (h/H), the Cholesterol-Saturated Fat Index (CSI) and ω-3/ω-6 ratio might have an effect on AIP. The purpose of this study is to find the possible relationship between dietary fat quality, and AIP and comparison of these indices among obese and non-obese volunteers.Methods: This study was a cross-sectional descriptive-analytic case-control study with 157 normal and overweight and obese volunteers (n=71 normal vs n=86 overweight and obese) in the age range of 18-65 years. Food intake, anthropometric indices, body composition, and lipid profile were measured. Results: Based on the present results, comparable biochemical parameters including TC (P=0.580), TG (P=0.362) and LDL (P=0.687) and HDL (P=0.151) among overweight/obese volunteers as compared to normal ones were noticed. Results of dietary fat quality, including Atherogenicity (AI) and Thrombogenicity (TI) hypo/hypercholesterolemic ratio (h/H), the Cholesterol-Saturated Fat Index (CSI) showed significantly higher AI (P=0.012) in the overweight/obese group as compared to the normal group. Whereas, h/H (P=0.034) and ω-6/ω-3 ratio (P=0.004) were significantly higher in normal weight volunteers. There was a positive correlation between AI, TI, CSI, SFA, MUFA, PUFA and ω-6/ω-3 ratio with AIP and negative correlation between h/H with AIP in both groups. Despite significancies of these corelations no strong relation was observed by doing multiple regression among normal and overweight/obese groups (R2=0.210, R2=0.387).Conclusions: In summary, the present study suggest a direct relationship between dietary fat quality, increased BMI, and lipid abnormalities with AIP. However, further large-scale studies are needed to have a clear conclusion in this regard.

Association of Dyslipidemia with Uterine Fibroid: A Case Control Study

2020 ◽  
Vol 33 (2) ◽  
pp. 100-106
Author(s):  
Shahzadi Afruza ◽  
AKM Azad Hossain ◽  
Jesmin Jahan ◽  
Asma Sharmin ◽  
Halima Naznin ◽  
...  
Keyword(s):  
Uterine Fibroid ◽  
Case Control Study ◽  
Statistical Significance ◽  
Hormonal Treatment ◽  
Case Control ◽  
Atherogenic Index ◽  
Control Group ◽  
Case Group ◽  
Control Study ◽  
Inpatient Department

Background & objective: Uterine fibroid (UF) is the most common gynaecological neoplasm. Despite the major public health impact of UF, little is known about their association. Some studies focused on the similarities between the common biological mechanisms underlying the development of UF and atherosclerotic plaques. So, it is possible to hypothesize that same atherogenic risk factors, such as dyslipidemia may play a role in UF pathogenesis. This study was carried out to investigate the lipid profile in patients with UF and to analyze the association of dyslipidemia with UF. Materials & Methods: This case-control study was carried out in the outpatient and inpatient Department of Obstetrics & Gynaecology, BSMMU, Shahbag, Dhaka over a period of 12 months between March 2017 to February 2018. Participants were 100 in number and aged between 18 and 45 years. Cases consisted of 50 women with uterine fibroids diagnosed by ultrasonography attending the outpatient and inpatient department of obstetrics and gynaecology, BSMMU, having no previous hormonal treatment. A similar number of age matched women without UF visiting the same gynaecological outpatient clinic for routine reasons were recruited as controls. Women who were postmenopausal, pregnant, diagnosed cases of malignant diseases, diagnosed cases of hypertension, diabetes mellitus, thyroid disease, CLD and CKD and women undergoing hormonal therapy were excluded from the study. Fasting lipid profiles were determined in blood samples taken from each participant. Atherogenic index was also calculated. Chi-square test was used for testing statistical significance. Statistical significance was set at p < 0⋅05. Results: Women with UF were found to have significantly higher levels of serum TC, TG and significantly lower level of HDL-C compared to the controls (p<0.05). The mean atherogenic index was 4.30±1.41 in case group and 2.86±0.97 in control group. The difference was statistically significant (p<0.05) between two groups. Conclusion: There is an association between dyslipidemia and UF. Women with UF have higher atherogenic index compared to women without UF. TAJ 2020; 33(2): 100-106

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