scholarly journals Reconstruction and Repairment with Mini- Plate and Bone Graft for HIV Positive Patients of Giant Cell Tumor of Long Bone: Retrospective Analysis of A Single-Center Experience

2021 ◽  
Author(s):  
Biao Xu ◽  
Rui Ma ◽  
Jie Wang ◽  
Qiang Zhang ◽  
Changsong Zhao ◽  
...  
Keyword(s):  
Bone Graft ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Proximal Tibia ◽  
Cell Tumor ◽  
Long Bone ◽  
Hiv Positive ◽  
Joint Function ◽  
Significant Difference ◽  
Mini Plate

Abstract Background To evaluate the effect of reconstruction and repairment with mini- plate and bone graft for HIV positive patients of giant cell tumor of long bone. Methods This research retrospectively analyzed 12 HIV positive patients with giant cell tumor of long bone, 11 male and 1 female, with a age range 16 to 68 years old (43.5 years old on average) were included. There were 5 cases of proximal tibia,3 cases of distal femur, 2 case of distal tibia, and 2 case of talus. From June 2012 to August 2020, curettage by ultrasonic scalpel were performed in all patients, combined with min- plate and bone graft treatment. All patients were followed up for 18–60 months. Limb function was evaluated by MSTS93 scoring system, and postoperative recurrence and distant metastasis, complications, MSTS93 score and fracture prognosis were observed. Results No local recurrence and pulmonary metastases was observed. After surgery, all the 12 patients showed good bone morphologic repair and reconstruction, good bone healing, good joint function, and no pathological fracture around the lesion. One case of giant cell tumor of proximal tibia showed mild articular surface collapse, and mild valgus deformity of knee joint, but good joint function. The MSTS93 score of the patients 6 months after the operation was 24–27 points (24.5 ± 1.08), with a significant difference (P < 0.05). Conclusion Reconstruction and repairment with mini- plate and bone graft for HIV positive patients of giant cell tumor of long bone has achieved satisfactory results. The mini- plate takes up little space and is flexible for reconstruction and fixation, significantly reducing complications such as surgical site infection, preserving joint function and avoiding amputation. It is a safe and effective treatment method.

scholarly journals Reconstruction and Repairment With Mini-plate and Bone Graft for HIV Positive Patients of Giant Cell Tumor of Long Bone: Retrospective Analysis of a Single-center Experience

2021 ◽  
Author(s):  
Biao Xu ◽  
Rui Ma ◽  
Qiang Zhang ◽  
Chang-song Zhao ◽  
Wen-sheng Zhang ◽  
...  
Keyword(s):  
Bone Graft ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Proximal Tibia ◽  
Cell Tumor ◽  
Long Bone ◽  
Hiv Positive ◽  
Joint Function ◽  
Significant Difference ◽  
Mini Plate

Abstract Background: To evaluate the effect of reconstruction and repairment with mini-plate and bone graft for HIV positive patients of giant cell tumor of long bone.Methods: This research retrospectively analyzed 12 HIV positive patients with giant cell tumor of long bone, 11 male and 1 female, with a age range 16 to 68 years old (43.5 years old on average) were included. There were 5 cases of proximal tibia，3 cases of distal femur, 2 case of distal tibia, and 2 case of talus. From June 2012 to August 2020, curettage by ultrasonic scalpel were performed in all patients, combined with min- plate and bone graft treatment. All patients were followed up for 18-60 months. Limb function was evaluated by MSTS93 scoring system, and postoperative recurrence and distant metastasis, complications, MSTS93 score and fracture prognosis were observed.Results: No local recurrence and pulmonary metastases was observed. After surgery, all the 12 patients showed good bone morphologic repair and reconstruction, good bone healing , good joint function, and no pathological fracture around the lesion. One case of giant cell tumor of proximal tibia showed mild articular surface collapse, and mild valgus deformity of knee joint, but good joint function. The MSTS93 score of the patients 6 months after the operation was 24-27 points (24.5±1.08), with a significant difference (P < 0.05).Conclusion: Reconstruction and repairment with mini-plate and bone graft for HIV positive patients of giant cell tumor of long bone has achieved satisfactory results. The mini- plate takes up little space and is flexible for reconstruction and fixation, significantly reducing complications such as surgical site infection, preserving joint function and avoiding amputation. It is a safe and effective treatment method.

scholarly journals Reconstruction and repair, using mini-plate and bone graft for persons living with HIV with giant cell tumor of long bone: retrospective analysis of a single-center experience

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Biao Xu ◽  
Rui Ma ◽  
Wen-sheng Zhang ◽  
Qiang Zhang ◽  
Chang-song Zhao ◽  
...  
Keyword(s):  
Bone Graft ◽  
Giant Cell Tumor ◽  
Retrospective Analysis ◽  
Giant Cell ◽  
Proximal Tibia ◽  
Cell Tumor ◽  
Long Bone ◽  
Hiv Positive ◽  
Joint Function ◽  
Mini Plate

Abstract Background To evaluate the effect of reconstruction and repair, using a mini-plate and bone graft for HIV -positive patients with giant cell tumor of long bone. Methods We conducted a retrospective analysis of 12 HIV positive patients with giant cell tumor of long bone. A non-HIV-positive cohort of patients, matched for age, sex, and disease type, was selected as the control group. From June 2012 to August 2020, curettage by ultrasonic scalpel was performed in all patients, combined with min- plate and bone graft treatment. All patients were followed- up for 18 to 60 months. Limb function was evaluated, using the MSTS93 scoring system, and any examples of postoperative recurrence, distant metastasis, complications, MSTS93 score, and fracture prognosis were recorded. Results The mean age of HIV group was 43.5 years. The ratio of men to women was 11: 1. In all cases the histopathological diagnosis was clear, except the patients with primary malignant giant cell tumor of bone, including five, three, two, and two cases in the proximal tibia, distal femur, distal tibia, and talus, respectively. Following their surgery, all patients were followed up with an average of 31.24 ± 11.84 months. No local recurrence or pulmonary metastases were observed. Post-surgery, all the 12 patients showed good bone morphologic repair and reconstruction, good bone healing, good joint function, and no pathological fractures around their lesion. In the HIV group, one case of giant cell tumor in the proximal tibia showed mild articular surface collapse and mild valgus deformity of the knee joint but retained good joint function. The MSTS scores of excellent or good in the two groups comprised 83.3%, thus, there was no significant difference between them (P > 0.05). Compared with preoperatively, the MSTS scores in the HIV group were significantly improved, ranging from 7 to 11 points preoperatively to 24 to 27 points postoperatively; this difference was statistically significant (P < 0.05). Conclusion Reconstruction and repair, using a mini-plate and bone graft for HIV -positive patients with giant cell tumor of long bone can achieve satisfactory results. The mini- plate requires little space and is flexible during reconstruction and fixation, significantly reducing complications such as surgical site infection, as well as preserving joint function and avoiding amputation; therefore, it is a safe and effective treatment method.

EKSISI DAN MEGA PROSTHESIS PADA GIANT CELL TUMOR PROXIMAL TIBIA (LAPORAN KASUS)

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Mujaddid Idulhaq ◽  
Bayu Sakti Jiwandono ◽  
Ariya Maulana Nasution ◽  
Handry TH
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Limb Salvage ◽  
Proximal Tibia ◽  
Skin Grafting ◽  
Cell Tumor ◽  
Limb Salvage Surgery ◽  
Thickness Skin ◽  
Split Thickness Skin Grafting ◽  
Muscular Flap

Giant cell tumor (GCT) merupakan tumor destruktif tulang yang muncul di antara dekade kedua dan keempat, lokasi predileksi umumnya pada epifisis tulang panjang. Pemilihan tatalaksana operasi sangat penting dan masih menjadi perdebatan. Sebagaimana masih beragamnya pilihan tindakan pembedahan. Klasifikasi Campanacci dapat digunakan sebagai acuan untuk panduan tatalaksana. Pada kasus ini kami melaporkan seorang wanita, usia 18 tahun dengan diagnosa giant cell tumor pada proximal tibia dextra dengan Campanacci grade III. Pasien telah menjalani operasi limb salvage tahap pertama berupa eksisi luas pada proximal tibia dextra dan knee arthrodesis. Setelah 4 bulan dilakukan operasi limb salvage tahap kedua yaitu knee arthroplasty dengan megaprosthesis. Untuk mencegah komplikasi implant expose, dilakukan muscular flap dan split thickness skin grafting (STSG). Setelah dilakukan evaluasi selama 4 bulan, klinis pasien baik, pasien dapat berjalan alat bantu dan tanpa nyeri, tidak ada komplikasi pada luka operasi dan fiksasi implan baik. Kesimpulan yang didapatkan bahwa limb salvage surgery pada giant cell tumor proximal tibia dapat dilakukan dengan tindakan rekonstruksi dua tahap. Teknik muscular flap dan split thickness skin grafting (STSG) dapat digunakan untuk mencegah terjadinya implant expose.

scholarly journals Surgical treatment outcome of giant cell tumor of distal ulna: En bloc resection vs. curettage and bone graft

2018 ◽  
Vol 32 (1) ◽  
pp. 249-253
Author(s):  
Khodamorad Jamshidi ◽  
Mehrdad Bahrabadi ◽  
Abolfazl Bagherifard ◽  
Mehdi Mohamadpour
Keyword(s):  
Treatment Outcome ◽  
Surgical Treatment ◽  
Bone Graft ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Cell Tumor ◽  
Distal Ulna ◽  
En Bloc

scholarly journals A Case Report of Giant Cell Tumor of Proximal Fibula in Children

2020 ◽  
Vol 4 (1) ◽  
pp. 64-67
Author(s):  
Sushil Adhikari ◽  
Arun Sigdel ◽  
Rajesh Kumar Sah ◽  
Luna Devkota
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Long Bone ◽  
Lytic Lesion ◽  
Radiographic Appearance ◽  
X Ray ◽  
Proximal Fibula ◽  
Aggressive Tumor

Giant cell tumour (GCT) is histopathologically benign tumor of long bone particularly in distal femur and the proximal tibia. It commonly occurs in adults of age 20-40 years but rare in children. GCT is considered to be locally aggressive tumor and tendency of recurrence is higher even after surgery. The clinical features are nonspecific, the principle symptoms are pain, swelling and limiting adjacent joint movements. Diagnosis is based on the radiographic appearance and histopathological findings .In our case X-ray showed ill defined lytic lesion on proximal fibula with cortical thinning and MRI finding revealed expansile lyticlesion in meta-epiphysis of right fibula 16×16×28mm adjacent to growth plate with fluid level. The sclerotic rim appears hypo intense on T1 & hyper intense on T2. Core needle biopsy showed giant cell tumor on proximal fibula. Considering the risk of recurrence wide local excision was done. Management of GCT of proximal fibula in young patient is critical for preventing recurrence and enhancing functional outcomes by saving adjacent anatomical structure. No evidence of local recurrence and metastasis was found in 24 months of follow up.

Giant cell tumor complicating Paget disease of long bone

2007 ◽  
Vol 36 (10) ◽  
pp. 973-978 ◽  
Author(s):  
Benjamin Hoch ◽  
George Hermann ◽  
Michael J. Klein ◽  
Ibrahim Fikry Abdelwahab ◽  
Dempsey Springfield
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Long Bone ◽  
Paget Disease

Patient-Specific Finite Element Analysis of Femoral Giant Cell Tumor Reconstructed Using Locking Plate System

2009 ◽  
Author(s):  
Jihui Li ◽  
Felasfa Wodajo
Keyword(s):  
Finite Element ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Locking Plate ◽  
Pathologic Fracture ◽  
Cell Tumor ◽  
Long Bone ◽  
Patient Specific ◽  
Element Analysis ◽  
Reconstruction Methods

Giant cell tumor (GCT) is a benign bone tumor that usually involves the end of long bone in young adults. GCT is locally aggressive, weakens the bone and can lead to pathologic fracture [1, 2]. Clinically, GCT is removed and the defect is reconstructed with bone cement, sometimes enhanced with intramedullary pins. However, there was no significant biomechanical advantage to using a cement plus pin construct over cement alone; clinical outcomes of both reconstruction methods were controversial [3–5]. While locking plates were recently adopted for GCT reconstruction, no biomechanics analysis has been performed to indicate its advantage over the cement alone or cement plus pin reconstruction. In this study we developed patient specific finite element (FE) models to compare the mechanical strengths of GCT reconstructed using cement alone and cement plus locking plate.

Sign in / Sign up

Export Citation Format

Share Document