scholarly journals Contrast-Enhanced and Microvascular Ultrasound Imaging Features of Testicular Lymphoma: Report of Five Cases and Review Literature

Author(s):  
Li Yang ◽  
Yuan Tao ◽  
Bao Meiling ◽  
Zhang Weixin ◽  
Hang Jing

Abstract Background: To retrospectively investigate the grey-scale, Doppler, contrast-enhanced and microvascular ultrasound of five patients with primary testicular lymphoma of our institute through review literature analysis.Methods: From January to November 2020, five patients with primary testicular lymphoma confirmed by histology were preoperatively investigated with a standardized sonographic protocol including contrast-enhanced and microvascular ultrasound.Results: Conventional ultrasound showed localized hypoechogenicity represented with solitary lesions(2 of 5), multiple lesions (2 of 5), or entire testicular involvement (1 of 5). And increased blood flow appeared by color Doppler ultrasound with straight vascular sign(4 of 5). In contrast-enhanced ultrasound images confirmed this pattern(4 of 5) and presented incresaed enhancement with enlarged range. On microvascular ultrasound imagings, all lesions were presented with straight and parallel course of intralesional vessels(5 of 5).Conclusions: Here, we identified the increased vascularity with enlarged range on contrast-enhanced ultrasound along with a linear nonbranching pattern by vascular sign on microvascular ultrasonographic of testicular lymphoma.

2018 ◽  
Vol 34 (4) ◽  
pp. 250-267 ◽  
Author(s):  
Emilio Quaia ◽  
Jean Michel Correas ◽  
Maithili Mehta ◽  
John T. Murchison ◽  
Antonio Giulio Gennari ◽  
...  

2020 ◽  
Author(s):  
Hongli Cao ◽  
Liang Fang ◽  
Lin Chen

Abstract Background: The value of contrast-enhanced ultrasound (CEUS) in differentiating between renal cell carcinoma (RCC) and angiomyolipoma (AML) was analyzed. The purpose of this study was to identify the independent indicators of CEUS for predicting RCC. Methods: A total of 172 renal tumors (150 RCCs, 22 AMLs) in 165 patients underwent conventional ultrasound (CUS) and CEUS examinations before radical or partial nephrectomy, and the features on CUS and CEUS were analyzed. Results: There were significant differences in echogenicity, blood flow signals in color Doppler flow imaging (CDFI), peak intensity, homogeneity of enhancement, wash in, wash out, and perilesional rim-like enhancement between RCC and AML ( P <0.05 for all). Multivariate analysis indicated that perilesional rim-like enhancement ( P =0.035, odds ratio [OR]=9.907, 95% confidence interval [CI]: 1.169-83.971) and fast wash out ( P =0.001, OR =9.755, 95%[CI]: 2.497-38.115) were independent indicators for predicting RCC. The area under the receiver operating characteristic (ROC) curve (AUC) for perilesional rim-like enhancement was 0.838 (95% CI:0.774-0.890) with 76.7% sensitivity and 90.9% specificity, while the AUC of fast wash out was 0.833 (95% CI:0.768-0.885) with 74.7% sensitivity and 81.8% specificity. Conclounsions: This study indicated that CEUS has value in differentiating RCC and AML. Present perilesional rim-like enhancement and fast wash out may be important indicators for predicting RCC. Key words: Renal cell carcinoma; angiomyolipoma; contrast-enhanced ultrasound; ultrasonography


Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Shuichi Tonomura ◽  
Kozue Saito ◽  
Hatsue Ishibashi-Ueda ◽  
Soichiro Abe ◽  
Kota Mori ◽  
...  

Introduction: Contrast-enhanced ultrasound (CEUS) using new contrast agents which offer a stable contrast effect in vivo is a noninvasive modality to detect vulnerability of carotid plaque, ulceration and neovascularization. A recent study showed the superiority for the detection of small ulcers using CEUS to color-Doppler ultrasound (CDUS), which used computed tomographic angiography (CTA) as the reference technique. Hypothesis: We assumed CEUS enables us to detect disruption of carotid plaques that could not be detected by CDUS and CTA. We aimed to investigate the diagnostic accuracy for detecting the disruption of the carotid plaques comparing with histopathological findings. Methods: From July 2010 to July 2015, we enrolled 68 internal carotid stenosis (ICS) patients undergoing carotid endarterectomy (CEA) and preoperatively examined CEUS using Perflubutane (Sonazoid), CDUS and CTA. We compared the findings of the plaque disruptions detected by these three modalities with the histopathological findings of ulceration and present/recent plaque rupture. Results: Of 68 subjects (age 72±6.6years old, 66 men), 44 (64%) had symptomatic ICS. Pathologically, ulceration and present/recent plaque rupture were found in 58 cases (85.3%). The diagnostic accuracy for detecting the disruption of carotid plaque by CEUS was significantly superior to other modalities (Table 1). CEUS could find disrupted carotid plaque more accurately than CTA. Conclusions: The assessment of the disruption of the plaques using CEUS was well correlated with pathological findings of plaque rupture, which may help us to evaluate the plaque vulnerability in vivo real time.


Diagnostics ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 51
Author(s):  
Wenying Zhou ◽  
Luyao Zhou

Biliary atresia is an aggressive liver disease of infancy and can cause death without timely surgical intervention. Early diagnosis of biliary atresia is critical to the recovery of bile drainage and long-term transplant-free survival. Ultrasound is recommended as the initial imaging strategy for the diagnosis of biliary atresia. Numerous ultrasound features have been proved helpful for the diagnosis of biliary atresia. In recent years, with the help of new technologies such as elastography ultrasound, contrast-enhanced ultrasound and artificial intelligence, the diagnostic performance of ultrasound has been significantly improved. In this review, various ultrasound features in the diagnosis of biliary atresia are summarized. A diagnostic decision flow chart for biliary atresia is proposed on the basis of the hybrid technologies, combining conventional ultrasound, elastography and contrast-enhanced ultrasound. In addition, the application of artificial intelligence in the diagnosis of biliary atresia with ultrasound images is also introduced.


2014 ◽  
Vol 86 (4) ◽  
pp. 378 ◽  
Author(s):  
Massimo Valentino ◽  
Michele Bertolotto ◽  
Pasquale Martino ◽  
Libero Barozzi ◽  
Pietro Pavlica

The increased use of ultrasound in patients with urological and andrological symptoms has given an higher detection of intra-testicular nodules. Most of these lesions are hypoechoic and their interpretation is often equivocal. Recently, new ultrasound techniques have been developed alongside of B-mode and color-Doppler ultrasound. Although not completely standardized, contrast-enhanced ultrasound (CEUS) and tissue elastography (TE), added to traditional ultrasonography, can provide useful information about the correct interpretation of incidentally detected non-palpable testicular nodules. The purpose of this review article is to illustrate these new techniques in the patient management.


2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Song Wang ◽  
Wei Yang ◽  
Hui Zhang ◽  
Qian Xu ◽  
Kun Yan

Objective. To investigate the value of contrast-enhanced ultrasound (CEUS) in transthoracic biopsy of peripheral lung and mediastinal lesions.Methods. Of 142 patients, 82 patients received CEUS before biopsy and were defined as CEUS group. The remaining 60 patients only underwent conventional ultrasound (US) before biopsy and were served as US group. The information of CEUS was used for selecting indication and instructing biopsy. The imaging features, number of punctures, diagnostic successful rate, and complication rate between the two groups were compared.Results. Necrosis was demonstrated in 43.9% of the lesions in CEUS group and in 6.7% of US group (P<0.001). Detection rate of lesion hidden in pulmonary atelectasis in CEUS group was 13.4%, which was statistically higher than 1.7% of US group (P=0.013). The diagnostic success rate was 96.3% for CEUS group and 80% for US group, respectively (P=0.002). The average number of punctures was2.5±0.7and2.6±0.6, respectively. There was no significant difference in complications between CEUS group and US group.Conclusions. CEUS could play an important role in selecting proper indication and improving diagnostic accuracy rate of lung biopsy.


2008 ◽  
Vol 47 (171) ◽  
Author(s):  
Hitoshi Maruyama ◽  
M Yoshikawa ◽  
O Yokosuka

Hepatocellular carcinoma has a decisive influence on the prognosis of cirrhotic patients, and the use of imaging modalities is essential for the screening, diagnosis and treatment of hepatocellular carcinoma. Ultrasound plays a major role among them, because it provides real-time and non-invasive observation by a simple and easy technique. In addition, ultrasound-guided needle puncture methods are frequently required for the diagnosis and/or treatment process of hepatocellular carcinoma. The development of digital technology has led to the detectability of blood flow by color Doppler ultrasound, and the sensitivity for tumor vascularity has shown remarkable improvement with the introduction of microbubble contrast agents. Moreover, near real-time three-dimensional ultrasound images are now available. These advancements in the ultrasound field have led to rapid progress in hepatocellular carcinoma management, and continuing advances are expected. This article reviews the current application of contrast-enhanced ultrasound for hepatocellular carcinoma in clinical practice.JNMA J Nepal Med Assoc. 2008 Jul-Sep;47(171):156-166.


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