scholarly journals A 10-Year Experience of Leiomyosarcoma of the Inferior Vena Cava

Author(s):  
Jun Pan ◽  
Chenyang Qiu ◽  
Yangyan He ◽  
Xing Xue ◽  
Donglin Li ◽  
...  

Abstract Background: Leiomyosarcoma of the inferior vena cava (IVC) is rare. The study reviewed patients with IVC leiomyosarcoma in our hospital in the past ten years.Methods: 20 patients diagnosed with IVC leiomyosarcoma between October 2010 and October 2020 were enrolled. Their clinical manifestations, treatments and follow-up results were analyzed.Results: The sarcoma was located in the lower IVC segment in six patients, with 13 in the middle IVC segment and one in the upper IVC segment. The median tumor size was 8.5 cm (range 2.5-27.0). Except for two patients who underwent partial resection, other patients underwent R0 resection. After resection, 16 patients (80%) had primary repair of the IVC, while four patients underwent ligation. Three patients with tumors invading the renal vein but not the kidney underwent renal vein revascularization. There was no perioperative death. During a mean follow-up of 37.7 months, seven patients died due to tumor metastasis, four patients were alive with the tumor recurrence and other nine patients were alive without recurrence.Conclusion: The perioperative mortality was low. The management of the IVC after tumor resection depended on the tumor location and size. R0 resection provided a chance for long term survival.

2016 ◽  
Vol 51 (1) ◽  
pp. 56-64 ◽  
Author(s):  
Marko Novak ◽  
Andraz Perhavec ◽  
Katherine E. Maturen ◽  
Snezana Pavlovic Djokic ◽  
Simona Jereb ◽  
...  

Abstract Background Leiomyosarcoma is a rare malignant mesenchymal tumour. Some cases of leiomyosarcoma of the renal vein (LRV) have been reported in the literature, but no analysis of data and search for prognostic factors have been done so far. The aim of this review was to describe the LRV, to analyse overall survival (OS), local recurrence free survival (LRFS) and distant metastases free survival (DMFS) in LRV world case series and to identify significant predictors of OS, LRFS and DMFS. Methods Cases from the literature based on PubMed search and a case from our institution were included. Results Sixty-seven patients with a mean age of 56.6 years were identified; 76.1% were women. Mean tumour size was 8.9 cm; in 68.7% located on the left side. Tumour thrombus extended into the inferior vena cava lumen in 13.4%. All patients but one underwent surgery (98.5%). After a median follow up of 24 months, the OS was 79.5%. LRFS was 83.5% after a median follow up of 21.5 months and DMFS was 76.1% after a median follow up of 22 months. Factors predictive of OS in univariate analysis were surgical margins, while factors predictive of LRFS were inferior vena cava luminal extension and grade. No factors predictive of DMFS were identified. In multivariate analysis none of the factors were predictive of OS, LRFS and DMFS. Conclusions Based on the literature review and presented case some conclusions can be made. LRV is usually located in the hilum of the kidney. It should be considered in differential diagnosis of renal and retroperitoneal masses, particularly in women over the age 40, on the left side and in the absence of haematuria. Core needle biopsy should be performed. Patients should be managed by sarcoma multidisciplinary team. LRV should be surgically removed, with negative margins.


Vascular ◽  
2011 ◽  
Vol 19 (4) ◽  
pp. 218-222 ◽  
Author(s):  
Cynthia Weber ◽  
Keith Jones ◽  
Ross Milner

We present a case of a 13-year-old boy who presented with a three-day history of left lower extremity swelling and a deep venous thrombosis. On further work-up he was discovered to have a large aneurysm of the inferior vena cava. After extensive discussion with his family, he underwent resection and primary repair of the inferior vena cava without complication. At a six-month follow up appointment, he was doing well with no recurrent aneurysmal degeneration on computed tomography scan imaging.


Phlebologie ◽  
2016 ◽  
Vol 45 (05) ◽  
pp. 322-324
Author(s):  
B. Burkert ◽  
Ph. Regeniter ◽  
A. Mumme ◽  
T. Hummel ◽  
D. Mühlberger

SummaryA case of bilateral iliofemoral thrombosis in a 17-year-old [male] patient is presented. It was only revealed during bilateral transfemoral thrombectomy that the thrombosis was due to previous inferior vena cava occlusion. This required a complex interventional reconstruction of the vena cava with secondary stenting of both renal veins. The postoperative venogram showed blood outflow from the left renal vein into the portal vein and from the right renal vein into the inferior vena cava via collaterals. At follow-up presentation, the patient was asymptomatic with normal findings on computed tomography scanning.


2012 ◽  
Vol 55 (6) ◽  
pp. 60S
Author(s):  
Elsie Gyang ◽  
Mohamed Zayed ◽  
E. John Harris ◽  
Jason T. Lee ◽  
Ronald L. Dalman ◽  
...  

2006 ◽  
Vol 32 (3) ◽  
pp. 403-406 ◽  
Author(s):  
Sevdenur Cizginer ◽  
Servet Tatli ◽  
Jeffrey Girshman ◽  
Joshua A. Beckman ◽  
Stuart G. Silverman

2021 ◽  
Vol 104 (9) ◽  
pp. 1459-1464

Objective: To determine the prevalence of inferior vena cava (IVC) anomalies in Thai patients who underwent contrast-enhanced computed tomography (CT) of the abdomen. Materials and Methods: Two radiologists retrospectively and independently reviewed the contrast-enhanced abdominal CT examinations in 1,429 Thai patients between August 1, 2018 and January 25, 2019 who met the inclusion criteria. Patients were included, if (a) their CT showed well visualized IVC, renal veins, and right ureter that were not obliterated by tumor, cyst, fluid collection, or intraperitoneal free fluid, (b) they had not undergone previous abdominal surgery that altered anatomical configuration of the IVC, renal veins, and right ureter. The presence of all IVC anomalies were recorded. Results: Among the 1,429 studied patients, 678 were male (47.4%) and 751 were female (52.6%). The prevalence of IVC anomalies was 3.5%. Five types of IVC anomalies were presented. The most common was circumaortic left renal vein in 24 patients or 48.0% of all IVC anomalies and 1.7% of the study population, followed by retroaortic left renal vein in 15 patients or 30.0 % of all IVC anomalies and 1.0% of the study population. Other IVC anomalies included double IVC, left IVC, and retrocaval ureter at 0.5%, 0.2%, and 0.1% of the study population, respectively. Conclusion: The prevalence of IVC anomalies in the present study differed from the previous studies conducted in other countries, which may be attributable to differences in race and ethnicity. Awareness of these anomalies is essential when evaluating routine CT examinations in asymptomatic patients. Their presence should be carefully noted in radiology reports to avoid anomaly-related complications. Keywords: Prevalence; IVC anomalies; Circumaortic left renal vein; Retroaortic left renal vein; Double IVC; Left IVC; Retrocaval ureter


2018 ◽  
Vol 11 (4) ◽  
pp. NP199-NP202 ◽  
Author(s):  
Carlos Domínguez-Massa ◽  
Félix Serrano-Martínez ◽  
Óscar R. Blanco-Herrera ◽  
Alberto Berbel-Bonillo ◽  
Fernando Hornero-Sos ◽  
...  

Thorough study is required to decide the appropriate management of hepatic tumors in children. We present a case report of a hepatic embryonal undifferentiated sarcoma with unfavorable prognosis in a nine-year-old girl. After undergoing a detailed cancer characteristics and extension study, a two-stage surgery approach was decided. The hepatic tumor resection was the first procedure to be performed. One week later, under cardiopulmonary bypass, deep hypothermia, and circulatory arrest, thrombectomy of the inferior vena cava and right atrium was accomplished, plus thromboendarterectomy of the right pulmonary artery. During a four-year follow-up, the patient continues to be disease-free.


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