scholarly journals Does Intradialytic Group Exercise Influence Malnutrition and Quality of Life in Maintenance Hemodialysis Patients? Evidence From an Experimental Study Using a Single-group Repeated-measures Design

2021 ◽  
Author(s):  
Li-Juan Zhou ◽  
Li-Yuan Zhang ◽  
Dan Shi ◽  
Qian Wang ◽  
Li Chen
Keyword(s):  
Quality Of Life ◽  
Repeated Measures ◽  
Exercise Programme ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Group Exercise ◽  
Repeated Measures Design ◽  
Maintenance Hemodialysis Patients

Abstract BackgroundMaintenance hemodialysis (MHD) patients is the representative of the sedentary group and often suffer from physical inactivity. Exercise rehabilitation is not widely included in dialysis care despite demonstrated health benefits. This study aimed to evaluate the effectiveness of intradialytic group exercise in MHD patients.MethodsThis was a single center, single-group repeated-measures design study, which included MHD patients in the hemodialysis center in Taizhou, China. The 12-week, 3 times per week intradialytic group exercise programme was conducted around 30 min during the first 2 hours of each dialysis session. Anthropometric indicators, including Body Mass Index (BMI), Triceps Skinfold Thickness (TSF), Mid-upper Arm Circumference (MUAC), Mid-arm Muscle Circumference (MAMC) Handgrip Strength (HGS), and quality of life were measured at baseline, 4-week follow up and 12-week follow up. Laboratory indicators, including Hemoglobin level (Hb), Total Protein (TP) and Albumin (Alb) were measured at baseline and 12-week follow up. The repeated-measures analysis of variance and Friedman test were used to compare the parametric and non‐parametric data at three time points, respectively. Paired t test was used to compare the continuous parametric between two time points.ResultsNinety patients were enrolled at baseline and seventy-five patients finished the whole 12-week exercise programme. There were 7 patients dropped out for losing of motivation and sample churn rate for losing of motivation was 7.8% (7/90). Participants reported significant improvements in most of the outcomes, TSF (F (2, 148) = 28.908, p = 0.000), MUMC (F (2, 148) = 3.1821, p = 0.044), MAMC (F (2, 148) = 27.795, p = 0.000), HGS (F (2, 148) = 42.383, p = 0.000), TP (F (t = -2.417, p = 0.018), ALB (t -3.190, p = 0.002), Hb (t = -2.353, p = 0.021), and QOL (F (2, 148) = 10.48, p = 0.000).ConclusionsThe positive results from this research suggest that intradialytic group exercise programme including aerobic exercise and resistance exercise is a safe and suitable exercise way for maintenance hemodialysis patients. This exercise can help keep patients’ motivation and improve nutritional status and quality of life in maintenance hemodialysis patients.

Depression and health-related quality of life in maintenance hemodialysis patients

2010 ◽  
Vol 73 (05) ◽  
pp. 374-380 ◽  
Author(s):  
H.C. Park ◽  
H.-B. Yoon ◽  
M.-J. Son ◽  
E.S. Jung ◽  
K.W. Joo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Maintenance Hemodialysis Patients

scholarly journals The association between health-related quality of life and mortality among hemodialysis patients

Medicina ◽  
2010 ◽  
Vol 46 (8) ◽  
pp. 531 ◽  
Author(s):  
Neda Kušleikaitė ◽  
Inga Bumblytė ◽  
Vytautas Kuzminskis ◽  
Rūta Vaičiūnienė
Keyword(s):  
Quality Of Life ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Health Related Quality ◽  
Point Increase ◽  
Related Quality ◽  
Health Related ◽  
Over Time

Introduction. Mortality rates for patients undergoing maintenance hemodialysis remain high. Published data regarding association between health-related quality of life (HRQOL) and mortality among hemodialysis patients are inconsistent. Very few data are published on the change in HRQOL over time as a predictor of mortality. The aim of this study was to assess whether HRQOL and change of it over time could be considered an independent predictor of mortality in hemodialysis patients. Material and methods. This prospective observational study enrolled 183 patients undergoing maintenance hemodialysis. HRQOL was measured annually 2004–2008 using a generic Short Form 36 questionnaire. Physical component summary (PSC) and mental component summary (MSC) scores were calculated. The change of the patient’s HRQOL over time was calculated as a difference between SF-36 scores of the first and the last HRQOL measurements. Results. The median follow-up was 48 months (range, 1–72 months). Cutoff values for HRQOL predicting mortality for PSC score was ≥35 and for MSC score was ≥45. In the model adjusted for age, sex, dialysis months, creatinine, albumin and hemoglobin levels, mortality risk decreased by 0.96 (95% CI, 0.95–0.99) for 1-point increase in the baseline PSC score and decreased by 0.97 (95% CI, 0.95–0.98) for 1-point increase in the baseline MSC score. A 1-point decline in the PSC score (relative risk, 1.11; 95% CI, 1.008–1.221) and MSC score (relative risk, 1.07; 95% CI, 1.002–1.149) over the period of follow-up were associated with a significant additional increase in mortality. Conclusions. Both baseline HRQOL and decline of HRQOL are independent predictors of mortality in hemodialysis patients.

scholarly journals Effects of l-Carnitine Supplementation in Maintenance Hemodialysis Patients: A Systematic Review

2002 ◽  
Vol 13 (3) ◽  
pp. 708-714
Author(s):  
Jean-Marc Hurot ◽  
Michel Cucherat ◽  
Margaret Haugh ◽  
Denis Fouque
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Exercise Capacity ◽  
Muscle Function ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Serum Triglycerides ◽  
Anemia Management ◽  
Maintenance Hemodialysis Patients

ABSTRACT. There are many causes for carnitine depletion during maintenance hemodialysis. Supplementation with l-carnitine in animals has been associated with improvement in some abnormalities also present in chronic renal failure. However, it is still controversial whether restoring plasma or tissue carnitine will correct clinical or biologic symptoms observed in maintenance hemodialysis. A systematic review is here performed to determine the effects of l-carnitine in maintenance hemodialysis patients. Eighty-three prospective trials were identified from 1978 to 1999 in which l-carnitine was randomly allocated in 21 trials. Change in serum triglycerides, cholesterol fractions, hemoglobin levels, erythropoietin dose, and other symptoms (muscle function, exercise capacity, and quality of life) were examined. A total of 482 patients in 18 trials were considered for analysis. There was no effect of l-carnitine on triglycerides, total cholesterol, or any of its fractions. Before the erythropoietin (EPO) era, l-carnitine treatment was associated with improved hemoglobin (P < 0.01) and with a decreased EPO dose (P < 0.01) and improved resistance to EPO when patients routinely received EPO. Muscle function, exercise capacity, and quality of life could not be reliably assessed because of the noncombinable nature of end points and the limited number of trials. In conclusion, l-carnitine cannot be recommended for treating the dyslipidemia of maintenance hemodialysis patients. By contrast, this review suggests a promising effect of l-carnitine on anemia management. The route of l-carnitine administration should be evaluated because there is no evidence as to the most efficient method of administration in maintenance hemodialysis.

scholarly journals Changes in Quality of Life in Older Hemodialysis Patients: A Cohort Study on Dialysis Outcomes and Practice Patterns

2020 ◽  
Vol 51 (8) ◽  
pp. 650-658
Author(s):  
Ayumi Ishiwatari ◽  
Shungo Yamamoto ◽  
Shingo Fukuma ◽  
Takeshi Hasegawa ◽  
Sachiko Wakai ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Practice Patterns ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Dialysis Vintage ◽  
Health Related Qol ◽  
Health Related ◽  
Dialysis Outcomes ◽  
Maintenance Hemodialysis Patients

Background: Despite improvements in dialysis treatment, mortality rates remain high, especially among older hemodialysis patients. Quality of life (QOL) among hemodialysis patients is strongly associated with higher risk of death. This study aimed to describe the health-related QOL and its change in older maintenance hemodialysis patients and to demonstrate characteristics associated with health-related QOL. Methods: Data on 892 maintenance hemodialysis patients aged 60 years or older who were surveyed using the Kidney Disease Quality of Life Short Form at baseline and 2 years after study enrollment in phases 4 (2009–2011) and 5 (2012–2014) of the Japanese Dialysis Outcomes and Practice Patterns Study were analyzed. We categorized participants into 3 age groups (60–69, 70–79, and ≥80 years) and described baseline physical component summary (PCS) and mental component summary (MCS) scores, as well as their distribution of changes after 2 years across each category. Results: Hemodialysis patients aged 70–79 years and ≥80 years had lower PCS scores than those aged 60–69 years (median: 70–79 years = 43.1; interquartile range [IQR], 35.2–49.4; ≥80 years = 38.8; IQR, 31.6–43.8; 60–69 years = 45.4; IQR, 37.5–51.4; p < 0.001). In contrast, MCS scores did not significantly differ by age category (70–79 years = 45.6; IQR, 38.4–53.7; ≥80 years = 45.4; IQR, 36.9–55.1; 60–69 years = 46.8; IQR, 39.5–55.7; p = 0.1). As dialysis vintage lengthened, the PCS score significantly became lower, whereas no association was found with change in the MCS score. The MCS score declined over time in older patients, especially among those aged 80 years and older after 2 years’ follow-up. Conclusions: Physical QOL became worse as dialysis vintage lengthened. In contrast, mental QOL declined over time within a relatively short period among older maintenance hemodialysis patients.

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