scholarly journals Procedural, In-Hospital and One Year Follow-Up Outcome of Success versus Failure Percutaneous Coronary Intervention in Chronic Total Occlusions

2015 ◽  
Vol 4 (11) ◽  
pp. 2229-2234
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Coronary Intervention ◽  
Chronic Total Occlusions ◽  
Percutaneous Coronary ◽  
One Year

Pitavastatin Combined with Ezetimibe Treatment was an Effective Approach to Non-IRA Lesion of ST-segment Elevation Myocardial Infarc-tion Patients with Primary Percutaneous Coronary Intervention

2020 ◽  
Vol 21 ◽  
Author(s):  
Bo Zhao ◽  
Guang Ping Li ◽  
Jian Jun Peng ◽  
Li Hui Ren ◽  
Li Cheng Lei ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Percutaneous Coronary Intervention ◽  
Coronary Intervention ◽  
Primary Pci ◽  
Gensini Score ◽  
St Segment Elevation ◽  
St Segment ◽  
Percutaneous Coronary ◽  
One Year

Objective: ST-segment elevation myocardial infarction (STEMI) patients with the multivessel disease have distinctive plaque characteristics in non-IRA lesions. Intensive statin therapy was a potential approach to treat STEMI patients with the non-IRA disease. However, there is still poor evidence about the therapeutic effect. In this study, we have evaluated the detailed therapeutic effect of statin plus ezetimibe intensive therapy. Method: For STEMI patients with non-IRA disease undergoing primary percutaneous coronary intervention (PCI), 183 control STEMI patients without non-IRA disease undergoing primary PCI, and 200 STEMI patients with non-IRA disease undergoing primary PCI were introduced into this study. 200 STEMI patients with non-IRA disease undergoing primary PCI were divided into Normal group, Intensive group, Normal & Combined group, and Intensive & Combined group. The baseline information for each participant was recorded. Meanwhile, the physiological and biochemical indicators of each member with different treatments were collected after one-year follow-up. Result: For STEMI patients with non-IRA disease undergoing primary PCI, no differences could be detected in multiple indexes such as OCT examination results, age, stroke, etc. However, diabetes mellitus, smoking, and coronary Gensini score were different between different groups (P<0.05). After one year follow-up, cholesterol, low-density lipoprotein, coronary Gensini score, thin-cap fibroatheroma, length of non-infarcted arterial lesions, non-infarct artery lesion range, myocardial infarction again, and revascularization again were significantly different between different groups (P<0.05). Conclusion: The results mentioned above suggested that pitavastatin combined with ezetimibe was an effective approach to STEMI patients with non-IRA disease undergoing primary PCI. The results obtained in this study have provided a novel way for the treatment of STEMI patients with non-IRA disease undergoing primary PCI.

Abstract P80: Initial and 12 Month Outcomes After Percutaneous Coronary Intervention in Australian Private Hospitals; Results From a National Multi-Centre Registry

2011 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
David Eccleston ◽  
Geoff Holt ◽  
Mark Horrigan ◽  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Coronary Intervention ◽  
Target Vessel Revascularisation ◽  
Target Vessel ◽  
Private Hospitals ◽  
Percutaneous Coronary ◽  
The Usa ◽  
Coronary Syndromes ◽  
One Year

Background: Several large multi-centre registries have evaluated outcomes after percutaneous coronary intervention (PCI) in the USA, however there is little data regarding the outcomes of patients in Australian Private hospitals. The aim of this study was to report the initial results of a new multi-centre registry. Methods: We prospectively enrolled consecutive patients (n=951) undergoing PCI to 1179 lesions at 6 Australian private hospitals from November 2008 to February 2010. Baseline patient/procedural data and in-hospital and 30 day and 12 month outcomes were recorded on case report forms. Data is stored electronically in the department of Epidemiology at Monash University. Results: The mean age ± SD was 67 ± 12 years. Females comprised 29.7 % (282/951), diabetics 26.6% (252/951), 33% (313/951) were obese (BMI>30) and 19% (181/951) had acute coronary syndromes. At least one DES was used in 64% of PCI (755/1179). In patients not taking Warfarin, 99.4% were taking aspirin and 98.8% clopidogrel at discharge. At 12 months, 10% (96/951) had undergone further revascularisation by PCI or CABG however only 1.1% (11/951) required target vessel revascularisation. Conclusion: A prospective, multicentre registry providing outcomes after PCI in private hospitals is feasible. Australian practice and in-hospital outcomes after PCI are consistent with those reported in American/European registries. One year follow up data will be presented. Outcomes at discharge (%) PCI Success 99.4 Death- Overall - Patients without pre-procedural shock 0.0 0.0 Myocardial infarction 2.4 Stroke 0.0 Urgent/ Early Target vessel revascularisation 0.6

Determinants of Significant Out-Of-Hospital Bleeding in Patients Undergoing Percutaneous Coronary Intervention

2018 ◽  
Vol 118 (11) ◽  
pp. 1997-2005 ◽  
Author(s):  
Sabato Sorrentino ◽  
Usman Baber ◽  
Bimmer Claessen ◽  
Anton Camaj ◽  
Birgit Vogel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Percutaneous Coronary Intervention ◽  
Coronary Intervention ◽  
Inclusion Criteria ◽  
Post Discharge ◽  
Free Trial ◽  
Tertiary Centre ◽  
Percutaneous Coronary ◽  
One Year

Background Although several variables have been identified as bleeding determinants (BDs), their occurrence and predictive value in patients undergoing percutaneous coronary intervention (PCI) in the real world remain unclear. We aimed to characterize the rate of BDs in patients undergoing PCI with stent implantation in a large volume tertiary centre. Methods We included patients undergoing coronary stenting at our institution from January 2012 to December 2016, and defined post-discharge bleeding (PDB) as bleeding requiring hospitalization or transfusion. Several BDs, identified by the PARIS bleeding and PRECISE-DAPT scores and inclusion criteria of the LEADERS FREE trial, were analysed. Results In a population of 10,406 subjects who underwent PCI, 2,938 patients (28.2%) had 1, 2,367 (22.8%) had 2 and 2,913 (28.0%) had ≥3 pre-specified BD. Compared with patients without PDB, subjects who experienced PDB were older (70.43 ± 11.94 vs. 65.90 ± 11.54 years, p < 0.0001) with a higher prevalence of common cardiovascular risk factors. One-year PDB occurred in 177 patients (2.4%), and consistently increased according to the number of BDs involved (1.12, 2.11 and 4.35%, respectively; p < 0.0001). Analogously, 1-year rates of post-discharge myocardial infarction or stent thrombosis increased according to the number of BDs (2.44, 3.38 and 4.87%, respectively; p < 0.0001). Only 7 BDs remained independently associated with PDB at 1 year, with anaemia, oral anticoagulant at discharge and malignancy representing the strongest predictors of such risk. Conclusion Many risk factors predispose to PDB; they were often clustered together and conferred additive PDB risk at 1-year of follow-up.

Abstract P222: Percutaneous Coronary Intervention in Hospitals Without Surgery on Site: One Year Follow-Up From a Longitudinal Registry

2011 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
Jorge Gonzalez ◽  
Ankur Gupta ◽  
Mohamad Alkhouli ◽  
Abdul Kashem ◽  
Kristy Scheiring ◽  
...  
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Carotid Artery Disease ◽  
Bare Metal Stents ◽  
Coronary Intervention ◽  
Metal Stents ◽  
Time Interval ◽  
Elective Percutaneous Coronary Intervention ◽  
Percutaneous Coronary ◽  
One Year

Background: The safety of performing elective percutaneous coronary intervention (PCI) in hospitals without surgery on site (SOS) has been questioned. We assessed the safety of this practice in a one year follow up study. Methods: 485 patients underwent elective (PCI) in two network hospitals without (SOS) were followed for one-year in a longitudinal registry. Baseline demographics, hemodynamics, and renal function were recorded for each patient before and after PCI. Clinical data were obtained at 6 weeks, 3, 6, 9, and 12 months. Results: Baseline demographics: Mean age was 68±12 years, 67% were male, BMI: 28.9±5.3. Comorbidities included heart failure-8.4%, carotid artery disease-7%, hypertension-80%, IDDM-9%, NIDDM-20%, PAD-6%, smoking-22%, prior PCI-31%. Systolic BP: 146±24 mmHg, diastolic BP: 79±15 mmHg, creatinine: 1.1±0.7mg/dl, Total Cholesterol: 157±40 mg/dl, EF: 52±14%. Total number of stents used was 558 (28% Bare-metal stents and 72% Drug eluted stents). Death, all cause readmissions, repeat PCI, CABG, and angina symptoms were recorded at each time interval (See table1 ). At one year 95% were taking aspirin and 89% were taking clopidogrel. No correlation was noted between clopidrogel use and repeat PCI. Conclusions: One year follow up after PCI in hospitals without SOS demonstrates acceptable rates of immediate complications and long term outcomes. The data suggest that elective PCI can be performed safely in hospitals without surgery on site. Time Interval Death Readmit Repeat PCI CABG Angina Symptoms 6 weeks 1% 7% 1.2% 1% 6.4% 3 months 0.4% 5% 0.6% 1% 6.9% 6 months 0.8% 7% 1.1% 0% 9.4% 9 months 0.4% 4% 9.3% 1% 10.4% 12 months 0.4% 3% 6.8% 0% 7.4%

Reduced levels of putative endothelial progenitor and CXCR4+ cells in coronary artery disease: Kinetics following percutaneous coronary intervention and association with clinical characteristics

2009 ◽  
Vol 101 (06) ◽  
pp. 1138-1146 ◽  
Author(s):  
Colin Gerard Egan ◽  
Francesca Caporali ◽  
Alda Huqi ◽  
Maria Cristina Zito ◽  
Marta Focardi ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Percutaneous Coronary Intervention ◽  
Vascular Injury ◽  
Coronary Intervention ◽  
Endothelial Progenitor ◽  
Percutaneous Coronary ◽  
Baseline Levels ◽  
Artery Disease ◽  
One Year

SummaryLevels of circulating endothelial progenitor cells (EPCs) and CXCR4-positive cells are decreased in patients with coronary artery disease (CAD); however, their ability to change in response to acute vascular injury remains to be elucidated. Progenitor and CXCR4-positive cells were analysed by flow cytometry from the peripheral blood of 23 healthy controls and 23 patients with CAD, of which 13 patients underwent angiogram and 10 patients received percutaneous coronary intervention (PCI) with stent implantation. Baseline levels of progenitor and CXCR4-positive cells were substantially reduced in CAD patients compared to controls, although they were still capable of increasing in response to vascular injury. Levels of progenitor and CXCR4-positive cells were increased to a greater extent in the PCI group compared to angiogram patients. At presentation, levels of putative endothelial progenitor and CXCR4-positive cells were found to be negatively correlated with disease severity. A one-year follow-up revealed that out of the cell populations examined, only levels of CXCR4-positive cells were positively correlated with angina frequency in the PCI group, but not in patients receiving angiogram. Baseline levels of progenitor cells are differentially increased depending upon the severity of vascular injury incurred, regardless of a significant deficit in baseline levels in CAD patients. Levels of putative EPCs and CXCR4-positive cells were negatively correlated with disease severity at presentation, however, only CXCR4-positive cells were associated with patient condition in a one-year follow-up.

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