scholarly journals Effect of Donor Parameters on the Yield of Plateletpheresis by Intermittent Flow Cell Separator

Author(s):  
Neetu Kukar ◽  
Anjali Handa ◽  
Ram Niwas Maharishi ◽  
Neha Syal ◽  
Harkiran Arora ◽  
...  
Blood ◽  
1974 ◽  
Vol 44 (3) ◽  
pp. 435-443 ◽  
Author(s):  
Mamoru Shoji ◽  
William R. Vogler

Abstract The usefulness of granulocyte transfusions is in part dependent upon the number of granulocytes transfused. The invention of the continuous-flow cell separator has made it possible to obtain granulocytes from normal donors. Efforts to improve the yield are under study. This controlled study was undertaken to determine the effect of a single dose of hydrocortisone on granulocyte yield from volunteer donors and on granulocyte bactericidal function. Twenty-two normal volunteers were randomized between no therapy or a single intravenous injection of 120 mg/sq m of hydrocortisone 2 hr prior to initiation of a 4-hr leukapheresis using the Aminco cell separator operated at 750 rpm and a flow rate of 41 ml/min. Significant increases in granulocyte yield and reductions in lymphocyte and monocyte yields were obtained in the hydrocortisone-treated group. Granulocytes from each group were equally effective in the phagocytosis of yeast particles and in vitro bactericidal activity.


Transfusion ◽  
1988 ◽  
Vol 28 (5) ◽  
pp. 470-473 ◽  
Author(s):  
F Norol ◽  
C Aubert ◽  
F Scotto ◽  
N Duedari

2001 ◽  
Vol 5 (1) ◽  
pp. 46-48 ◽  
Author(s):  
Kazuo Tsubaki ◽  
Takeshi Ariyama ◽  
Toshihisa Ueno ◽  
Yukito Kogi ◽  
Shiho Itoh ◽  
...  

1991 ◽  
Vol 12 (3) ◽  
pp. 183-187 ◽  
Author(s):  
P.K. Baker ◽  
E.G.H. Rhodes ◽  
J.K.M. Duguid

1987 ◽  
Vol 10 (1) ◽  
pp. 57-60
Author(s):  
S. Pennisi ◽  
E. Del Fabro

The main disadvantages of the discontinuous flow cell separator Haemonetics 30 (Haemonetics Corp. Natick, Mass.) compared to continuous flow separators are that there is a longer course procedure and a larger amount of donor's blood in extracorporeal circulation. These drawbacks can be reduced by means of a simple technical set-up. Since plasma reinfusion may commence as soon as the bowl filling stage is completed, the amount of blood in extracorporeal circulation can be greatly reduced simply by substituting a three-way setfor the two-way reinfusion set (BT 293).


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